Predicted complex interactions
CCL25_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 97 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 97 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | SER 116 | 3.29x29 | HBDonor |
| GLN 1 | NTc.Cm29 | SER 116 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm29 | TYR 176 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 289 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 289 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | ASN 100 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm27 | ARG 183 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | ARG 183 | - | VdWContact |
| PHE 4 | NTc.Cm26 | LYS 33 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 36 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 36 | 1.27x27 | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 37 | 1.28x28 | HBAcceptor |
| PHE 4 | NTc.Cm26 | ARG 37 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 183 | - | HBAcceptor |
| PHE 4 | NTc.Cm26 | ARG 183 | - | VdWContact |
| PHE 4 | NTc.Cm26 | ARG 263 | 6.58x58 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 282 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 282 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | ILE 285 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ILE 285 | 7.35x34 | VdWContact |
| PHE 4 | NTc.Cm26 | GLN 286 | 7.36x35 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 286 | 7.36x35 | VdWContact |
| GLU 5 | NTc.Cm25 | LYS 33 | - | VdWContact |
| GLU 5 | NTc.Cm25 | ASN 179 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | ASN 179 | - | VdWContact |
| GLU 5 | NTc.Cm25 | ASN 181 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | ASN 181 | - | VdWContact |
| GLU 5 | NTc.Cm25 | ARG 183 | - | Anionic |
| GLU 5 | NTc.Cm25 | ARG 183 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ILE 30 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | CYS 31 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ILE 32 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 33 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 33 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ARG 37 | 1.28x28 | Anionic |
| ASP 6 | NTc.Cm24 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 6 | NTc.Cm24 | ARG 37 | 1.28x28 | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 31 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 31 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 31 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LYS 33 | - | Anionic |
| LEU 9 | NTc.Cm21 | CYS 31 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 275 | 7.25x24 | VdWContact |
| ALA 10 | NTc.Cm20 | LEU 29 | - | Hydrophobic |
| ALA 10 | NTc.Cm20 | LEU 29 | - | VdWContact |
| HIS 12 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | TYR 27 | - | PiStacking |
| HIS 12 | NTc.Cm18 | TYR 27 | - | VdWContact |
| HIS 12 | NTc.Cm18 | LEU 29 | - | HBDonor |
| HIS 12 | NTc.Cm18 | LEU 29 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | LEU 29 | - | VdWContact |
| ILE 15 | NTc.Cm15 | TYR 27 | - | Hydrophobic |
| ALA 18 | NTc.Cm12 | TYR 22 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 24 | - | VdWContact |
| ARG 21 | NTc.Cm9 | GLU 14 | - | Cationic |
| ARG 21 | NTc.Cm9 | GLU 14 | - | HBDonor |
| ARG 21 | NTc.Cm9 | GLU 14 | - | VdWContact |
| ARG 22 | NTc.Cm8 | MET 18 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | MET 18 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 22 | - | VdWContact |
| GLU 30 | CX.1 | ILE 187 | - | Hydrophobic |
| GLU 30 | CX.1 | ILE 187 | - | VdWContact |
| VAL 31 | CX.5 | PHE 188 | - | VdWContact |
| VAL 31 | CX.5 | LYS 197 | 5.35x36 | Hydrophobic |
| VAL 31 | CX.5 | ILE 267 | 6.62x62 | Hydrophobic |
| SER 32 | cxb1.1 | PRO 186 | 45.52x52 | VdWContact |
| SER 34 | cxb1.5 | LYS 33 | - | HBAcceptor |
| SER 34 | cxb1.5 | LYS 33 | - | VdWContact |
| CYS 35 | cxb1.7 | LYS 33 | - | Anionic |
| ASN 36 | cxb1.8 | ASP 266 | 6.61x61 | HBDonor |
| ASN 36 | cxb1.8 | ASP 266 | 6.61x61 | VdWContact |
| ASN 36 | cxb1.8 | ILE 267 | 6.62x62 | Hydrophobic |
| ILE 41 | cxb1.16 | ILE 30 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 24 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 24 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 24 | - | VdWContact |
| LYS 50 | b1b2.2 | ILE 30 | - | Hydrophobic |
| LYS 50 | b1b2.2 | ILE 30 | - | VdWContact |
| VAL 51 | b1b2.3 | TYR 27 | - | Hydrophobic |
| VAL 51 | b1b2.3 | TYR 27 | - | VdWContact |
| PRO 55 | b1b2.7 | ARG 190 | - | HBAcceptor |
| PRO 55 | b1b2.7 | ARG 190 | - | VdWContact |
