Predicted complex interactions
CCL27_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 84
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | TRP 97 | 2.60x60 | Hydrophobic |
| PHE 1 | NTc.Cm32 | SER 116 | 3.29x29 | VdWContact |
| PHE 1 | NTc.Cm32 | GLN 172 | 4.60x61 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 176 | 4.64x65 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 176 | 4.64x65 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 256 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 289 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm32 | GLU 289 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm32 | GLU 289 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 97 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 97 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 119 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 289 | 7.39x38 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 289 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 293 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm30 | ARG 263 | 6.58x58 | VdWContact |
| LEU 3 | NTc.Cm30 | ILE 285 | 7.35x34 | Hydrophobic |
| PRO 4 | NTc.Cm29 | ARG 183 | - | Hydrophobic |
| PRO 4 | NTc.Cm29 | ARG 183 | - | VdWContact |
| PRO 4 | NTc.Cm29 | CYS 184 | 45.50x50 | VdWContact |
| PRO 4 | NTc.Cm29 | ILE 185 | 45.51x51 | Hydrophobic |
| PRO 4 | NTc.Cm29 | ILE 185 | 45.51x51 | VdWContact |
| PRO 5 | NTc.Cm28 | ARG 37 | 1.28x28 | Hydrophobic |
| PRO 5 | NTc.Cm28 | ARG 37 | 1.28x28 | VdWContact |
| PRO 5 | NTc.Cm28 | ARG 183 | - | HBAcceptor |
| PRO 5 | NTc.Cm28 | ARG 183 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | ARG 183 | - | VdWContact |
| SER 6 | NTc.Cm27 | LYS 33 | - | VdWContact |
| SER 6 | NTc.Cm27 | VAL 36 | 1.27x27 | VdWContact |
| THR 7 | NTc.Cm26 | ARG 183 | - | VdWContact |
| ALA 8 | NTc.Cm25 | ILE 30 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 31 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 31 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 31 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 31 | - | VdWContact |
| THR 11 | NTc.Cm22 | CYS 31 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | GLU 28 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | GLU 28 | - | VdWContact |
| GLN 12 | NTc.Cm21 | THR 273 | - | VdWContact |
| TYR 14 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | GLU 28 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | TYR 27 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | TYR 27 | - | VdWContact |
| SER 19 | NTc.Cm14 | TYR 22 | - | HBDonor |
| SER 19 | NTc.Cm14 | TYR 22 | - | VdWContact |
| LYS 21 | NTc.Cm12 | GLU 17 | - | Cationic |
| LYS 21 | NTc.Cm12 | GLU 17 | - | HBDonor |
| LYS 21 | NTc.Cm12 | GLU 17 | - | VdWContact |
| LYS 21 | NTc.Cm12 | TYR 22 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 24 | - | VdWContact |
| LEU 22 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| ARG 24 | NTc.Cm9 | GLU 14 | - | Cationic |
| ARG 24 | NTc.Cm9 | GLU 14 | - | HBDonor |
| ARG 24 | NTc.Cm9 | GLU 14 | - | VdWContact |
| ALA 34 | CX.5 | LYS 197 | 5.35x36 | HBAcceptor |
| ALA 34 | CX.5 | LYS 197 | 5.35x36 | VdWContact |
| ASP 35 | cxb1.1 | ILE 187 | - | Hydrophobic |
| ASP 35 | cxb1.1 | PHE 188 | - | HBAcceptor |
| ASP 35 | cxb1.1 | PHE 188 | - | VdWContact |
| ASP 35 | cxb1.1 | LYS 197 | 5.35x36 | HBAcceptor |
| ASP 35 | cxb1.1 | LYS 197 | 5.35x36 | VdWContact |
| ASP 37 | cxb1.5 | ILE 185 | 45.51x51 | Hydrophobic |
| HIS 39 | cxb1.7 | ILE 267 | 6.62x62 | Hydrophobic |
| HIS 39 | cxb1.7 | ILE 267 | 6.62x62 | VdWContact |
| VAL 44 | cxb1.15 | ILE 30 | - | Hydrophobic |
| LEU 47 | cxb1.18 | TYR 24 | - | Hydrophobic |
| LEU 47 | cxb1.18 | TYR 24 | - | VdWContact |
| ARG 50 | B1.2 | LEU 29 | - | Hydrophobic |
| SER 51 | B1.3 | LEU 29 | - | VdWContact |
| SER 51 | B1.3 | ILE 30 | - | HBAcceptor |
| SER 51 | B1.3 | ILE 30 | - | VdWContact |
| ILE 52 | B1.4 | TYR 24 | - | Hydrophobic |
| ILE 52 | B1.4 | TYR 27 | - | Hydrophobic |
| ILE 52 | B1.4 | TYR 27 | - | VdWContact |
| ILE 52 | B1.4 | GLU 28 | - | VdWContact |
| ILE 52 | B1.4 | LEU 29 | - | Hydrophobic |
| CYS 53 | B1.5 | GLU 28 | - | HBDonor |
| CYS 53 | B1.5 | GLU 28 | - | Hydrophobic |
| CYS 53 | B1.5 | GLU 28 | - | VdWContact |
| CYS 53 | B1.5 | ILE 30 | - | VdWContact |
| MET 87 | H.5 | ARG 190 | - | HBAcceptor |
| MET 87 | H.5 | ARG 190 | - | VdWContact |
