Predicted complex interactions
CCL28_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm29 | PRO 186 | 45.52x52 | VdWContact |
| SER 1 | NTc.Cm29 | PHE 188 | - | VdWContact |
| SER 1 | NTc.Cm29 | GLN 201 | 5.39x40 | VdWContact |
| GLU 2 | NTc.Cm28 | ARG 263 | 6.58x58 | Anionic |
| GLU 2 | NTc.Cm28 | ARG 263 | 6.58x58 | HBAcceptor |
| GLU 2 | NTc.Cm28 | ARG 263 | 6.58x58 | VdWContact |
| ALA 3 | NTc.Cm27 | TYR 176 | 4.64x65 | Hydrophobic |
| ALA 3 | NTc.Cm27 | TYR 176 | 4.64x65 | VdWContact |
| ALA 3 | NTc.Cm27 | ILE 185 | 45.51x51 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 119 | 3.32x32 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TYR 119 | 3.32x32 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 256 | 6.51x51 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TYR 256 | 6.51x51 | VdWContact |
| ILE 4 | NTc.Cm26 | GLU 289 | 7.39x38 | Hydrophobic |
| ILE 4 | NTc.Cm26 | GLU 289 | 7.39x38 | VdWContact |
| LEU 5 | NTc.Cm25 | LEU 44 | 1.35x35 | Hydrophobic |
| LEU 5 | NTc.Cm25 | LEU 44 | 1.35x35 | VdWContact |
| LEU 5 | NTc.Cm25 | LEU 48 | 1.39x39 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TRP 97 | 2.60x60 | Hydrophobic |
| LEU 5 | NTc.Cm25 | GLU 289 | 7.39x38 | VdWContact |
| PRO 6 | NTc.Cm24 | ILE 185 | 45.51x51 | Hydrophobic |
| ILE 7 | NTc.Cm23 | ARG 37 | 1.28x28 | Hydrophobic |
| ILE 7 | NTc.Cm23 | ARG 37 | 1.28x28 | VdWContact |
| ILE 7 | NTc.Cm23 | ASN 100 | 2.63x63 | VdWContact |
| ILE 7 | NTc.Cm23 | ARG 183 | - | VdWContact |
| ALA 8 | NTc.Cm22 | LYS 33 | - | Hydrophobic |
| ALA 8 | NTc.Cm22 | VAL 36 | 1.27x27 | Hydrophobic |
| ALA 8 | NTc.Cm22 | ARG 37 | 1.28x28 | HBAcceptor |
| ALA 8 | NTc.Cm22 | ARG 37 | 1.28x28 | VdWContact |
| ALA 8 | NTc.Cm22 | ASP 282 | 7.32x31 | Hydrophobic |
| ALA 8 | NTc.Cm22 | ASP 282 | 7.32x31 | VdWContact |
| SER 9 | NTc.Cm21 | LYS 33 | - | VdWContact |
| SER 9 | NTc.Cm21 | ARG 183 | - | HBAcceptor |
| SER 9 | NTc.Cm21 | ARG 183 | - | VdWContact |
| SER 10 | NTc.Cm20 | CYS 31 | - | VdWContact |
| SER 10 | NTc.Cm20 | LYS 33 | - | HBAcceptor |
| SER 10 | NTc.Cm20 | LYS 33 | - | VdWContact |
| SER 10 | NTc.Cm20 | ARG 37 | 1.28x28 | HBAcceptor |
| SER 10 | NTc.Cm20 | ARG 37 | 1.28x28 | VdWContact |
| CYS 11 | NTc.Cm19 | CYS 31 | - | HBAcceptor |
| CYS 11 | NTc.Cm19 | CYS 31 | - | VdWContact |
| THR 13 | NTc.Cm17 | CYS 31 | - | Hydrophobic |
| GLU 14 | NTc.Cm16 | GLU 28 | - | Hydrophobic |
| SER 16 | NTc.Cm14 | GLU 28 | - | HBAcceptor |
| SER 16 | NTc.Cm14 | GLU 28 | - | VdWContact |
| HIS 18 | NTc.Cm12 | TYR 27 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 27 | - | VdWContact |
| SER 20 | NTc.Cm10 | TYR 22 | - | HBDonor |
| SER 20 | NTc.Cm10 | TYR 22 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 22 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 22 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 24 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 24 | - | VdWContact |
| LEU 23 | NTc.Cm7 | TYR 27 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 27 | - | VdWContact |
| ARG 26 | NTc.Cm4 | TYR 22 | - | CationPi |
| ARG 26 | NTc.Cm4 | TYR 22 | - | VdWContact |
| ALA 35 | cxb1.6 | LYS 197 | 5.35x36 | HBAcceptor |
| ALA 35 | cxb1.6 | LYS 197 | 5.35x36 | VdWContact |
| ASP 36 | cxb1.7 | ILE 187 | - | Hydrophobic |
| ASP 36 | cxb1.7 | ILE 187 | - | VdWContact |
| ASP 36 | cxb1.7 | PHE 188 | - | HBAcceptor |
| ASP 36 | cxb1.7 | PHE 188 | - | VdWContact |
| ASP 36 | cxb1.7 | LYS 197 | 5.35x36 | HBAcceptor |
| ASP 36 | cxb1.7 | LYS 197 | 5.35x36 | VdWContact |
| ASP 38 | cxb1.10 | ILE 185 | 45.51x51 | Hydrophobic |
| ASP 38 | cxb1.10 | ILE 185 | 45.51x51 | VdWContact |
| ILE 45 | B1.1 | ILE 30 | - | Hydrophobic |
| VAL 48 | B1.4 | TYR 24 | - | Hydrophobic |
| LYS 49 | B1.5 | GLU 17 | - | Cationic |
| LYS 49 | B1.5 | GLU 17 | - | HBDonor |
| LYS 49 | B1.5 | GLU 17 | - | VdWContact |
| ARG 50 | B1.6 | TYR 11 | - | Hydrophobic |
| ARG 50 | B1.6 | TYR 11 | - | VdWContact |
| ARG 50 | B1.6 | GLU 14 | - | Cationic |
| ARG 50 | B1.6 | GLU 14 | - | HBDonor |
| ARG 50 | B1.6 | GLU 14 | - | VdWContact |
| ARG 51 | B1.7 | TYR 13 | - | Hydrophobic |
| ARG 51 | B1.7 | LEU 29 | - | Hydrophobic |
| ARG 52 | b1b2.4 | TYR 11 | - | HBDonor |
| ARG 52 | b1b2.4 | TYR 11 | - | VdWContact |
| ARG 52 | b1b2.4 | ILE 30 | - | HBAcceptor |
| ARG 52 | b1b2.4 | ILE 30 | - | Hydrophobic |
| ARG 52 | b1b2.4 | ILE 30 | - | VdWContact |
| ILE 53 | b1b2.6 | TYR 24 | - | Hydrophobic |
| ILE 53 | b1b2.6 | TYR 27 | - | Hydrophobic |
| ILE 53 | b1b2.6 | TYR 27 | - | VdWContact |
| ILE 53 | b1b2.6 | LEU 29 | - | Hydrophobic |
| CYS 54 | b1b2.7 | GLU 28 | - | HBDonor |
| CYS 54 | b1b2.7 | GLU 28 | - | Hydrophobic |
| CYS 54 | b1b2.7 | GLU 28 | - | VdWContact |
| CYS 54 | b1b2.7 | ILE 30 | - | VdWContact |
| HIS 85 | H.7 | ILE 187 | - | Hydrophobic |
| HIS 85 | H.7 | ILE 187 | - | VdWContact |
