Predicted complex interactions
CCL3_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 77
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | TYR 176 | 4.64x65 | VdWContact |
| SER 1 | NTc.Cm33 | GLU 289 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm33 | GLU 289 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm32 | LEU 48 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TRP 97 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TRP 97 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm32 | TYR 119 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TYR 119 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm32 | GLU 289 | 7.39x38 | VdWContact |
| ALA 3 | NTc.Cm31 | ILE 285 | 7.35x34 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 286 | 7.36x35 | HBAcceptor |
| ALA 3 | NTc.Cm31 | GLN 286 | 7.36x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 286 | 7.36x35 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 289 | 7.39x38 | HBDonor |
| ALA 3 | NTc.Cm31 | GLU 289 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | LEU 44 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ALA 101 | 2.64x64 | Hydrophobic |
| ASP 5 | NTc.Cm29 | ASN 100 | 2.63x63 | HBAcceptor |
| ASP 5 | NTc.Cm29 | ASN 100 | 2.63x63 | VdWContact |
| ASP 5 | NTc.Cm29 | ARG 183 | - | VdWContact |
| ASP 5 | NTc.Cm29 | CYS 184 | 45.50x50 | VdWContact |
| ASP 5 | NTc.Cm29 | ILE 185 | 45.51x51 | Hydrophobic |
| ASP 5 | NTc.Cm29 | ILE 185 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm28 | VAL 36 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm28 | VAL 36 | 1.27x27 | VdWContact |
| THR 6 | NTc.Cm28 | ARG 37 | 1.28x28 | VdWContact |
| THR 6 | NTc.Cm28 | ARG 183 | - | HBAcceptor |
| THR 6 | NTc.Cm28 | ARG 183 | - | VdWContact |
| THR 6 | NTc.Cm28 | ASP 282 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | ASP 282 | 7.32x31 | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 33 | - | VdWContact |
| THR 8 | NTc.Cm26 | LYS 33 | - | HBAcceptor |
| THR 8 | NTc.Cm26 | LYS 33 | - | VdWContact |
| THR 8 | NTc.Cm26 | ARG 183 | - | VdWContact |
| ALA 9 | NTc.Cm25 | ILE 30 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | CYS 31 | - | VdWContact |
| CYS 10 | NTc.Cm24 | CYS 31 | - | HBAcceptor |
| CYS 10 | NTc.Cm24 | CYS 31 | - | HBDonor |
| CYS 10 | NTc.Cm24 | CYS 31 | - | VdWContact |
| CYS 10 | NTc.Cm24 | LYS 33 | - | Anionic |
| PHE 12 | NTc.Cm22 | CYS 31 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 31 | - | VdWContact |
| PHE 12 | NTc.Cm22 | ILE 272 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | ILE 272 | - | VdWContact |
| PHE 12 | NTc.Cm22 | THR 273 | - | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 275 | 7.25x24 | Hydrophobic |
| PHE 12 | NTc.Cm22 | SER 278 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm21 | LEU 29 | - | VdWContact |
| TYR 14 | NTc.Cm20 | LEU 29 | - | VdWContact |
| ARG 17 | NTc.Cm17 | TYR 22 | - | Hydrophobic |
| ARG 17 | NTc.Cm17 | TYR 22 | - | VdWContact |
| PRO 20 | NTc.Cm14 | MET 18 | - | Hydrophobic |
| ASN 22 | NTc.Cm11 | MET 18 | - | VdWContact |
| PHE 23 | NTc.Cm10 | MET 18 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | MET 18 | - | VdWContact |
| GLU 29 | NTc.Cm4 | ARG 190 | - | Anionic |
| GLU 29 | NTc.Cm4 | ARG 190 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | ARG 190 | - | VdWContact |
| SER 32 | NTc.Cm1 | PRO 186 | 45.52x52 | VdWContact |
| SER 32 | NTc.Cm1 | LYS 197 | 5.35x36 | HBAcceptor |
| SER 32 | NTc.Cm1 | LYS 197 | 5.35x36 | VdWContact |
| GLN 33 | CX.1 | PRO 186 | 45.52x52 | Hydrophobic |
| GLN 33 | CX.1 | PRO 186 | 45.52x52 | VdWContact |
| SER 35 | cxb1.1 | ASP 266 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | ILE 272 | - | HBDonor |
| SER 35 | cxb1.1 | ILE 272 | - | VdWContact |
| ILE 40 | cxb1.8 | ILE 30 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 24 | - | CationPi |
| ARG 47 | B1.2 | TYR 24 | - | VdWContact |
| GLN 48 | B1.3 | ILE 30 | - | Hydrophobic |
| GLN 48 | B1.3 | ILE 30 | - | VdWContact |
| VAL 49 | B1.4 | TYR 27 | - | Hydrophobic |
| VAL 49 | B1.4 | TYR 27 | - | VdWContact |
| VAL 49 | B1.4 | ILE 30 | - | VdWContact |
| CYS 50 | B1.5 | LEU 29 | - | Hydrophobic |
| CYS 50 | B1.5 | ILE 30 | - | Hydrophobic |
| CYS 50 | B1.5 | ILE 30 | - | VdWContact |
