Predicted complex interactions
CCL4_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TRP 97 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TRP 97 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm33 | SER 116 | 3.29x29 | VdWContact |
| ALA 1 | NTc.Cm33 | TYR 176 | 4.64x65 | HBDonor |
| ALA 1 | NTc.Cm33 | TYR 176 | 4.64x65 | Hydrophobic |
| ALA 1 | NTc.Cm33 | TYR 176 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 97 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 97 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 119 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 289 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm31 | ARG 263 | 6.58x58 | VdWContact |
| MET 3 | NTc.Cm31 | ILE 285 | 7.35x34 | Hydrophobic |
| MET 3 | NTc.Cm31 | GLU 289 | 7.39x38 | HBDonor |
| MET 3 | NTc.Cm31 | GLU 289 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm30 | GLN 286 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 289 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 289 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | LEU 44 | 1.35x35 | VdWContact |
| SER 5 | NTc.Cm29 | ASN 100 | 2.63x63 | VdWContact |
| ASP 6 | NTc.Cm28 | ARG 183 | - | Anionic |
| ASP 6 | NTc.Cm28 | ARG 183 | - | HBAcceptor |
| ASP 6 | NTc.Cm28 | ARG 183 | - | VdWContact |
| ASP 6 | NTc.Cm28 | ILE 185 | 45.51x51 | Hydrophobic |
| ASP 6 | NTc.Cm28 | ILE 185 | 45.51x51 | VdWContact |
| PRO 7 | NTc.Cm27 | VAL 36 | 1.27x27 | Hydrophobic |
| PRO 7 | NTc.Cm27 | ARG 37 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 33 | - | VdWContact |
| THR 9 | NTc.Cm25 | LYS 33 | - | HBAcceptor |
| THR 9 | NTc.Cm25 | LYS 33 | - | VdWContact |
| THR 9 | NTc.Cm25 | ARG 183 | - | VdWContact |
| ALA 10 | NTc.Cm24 | ILE 30 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | ILE 30 | - | VdWContact |
| ALA 10 | NTc.Cm24 | CYS 31 | - | VdWContact |
| CYS 11 | NTc.Cm23 | ILE 30 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 31 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 31 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 31 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LYS 33 | - | Anionic |
| CYS 12 | NTc.Cm22 | ILE 30 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 31 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 31 | - | VdWContact |
| PHE 13 | NTc.Cm21 | LYS 33 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ILE 272 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ILE 272 | - | VdWContact |
| PHE 13 | NTc.Cm21 | THR 273 | - | VdWContact |
| PHE 13 | NTc.Cm21 | SER 278 | 7.28x27 | VdWContact |
| SER 14 | NTc.Cm20 | GLU 28 | - | HBDonor |
| SER 14 | NTc.Cm20 | GLU 28 | - | VdWContact |
| TYR 15 | NTc.Cm19 | GLU 28 | - | VdWContact |
| THR 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLN 26 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| LEU 20 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 13 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 13 | - | VdWContact |
| ASN 23 | NTc.Cm11 | ASP 10 | - | HBDonor |
| ASN 23 | NTc.Cm11 | ASP 10 | - | VdWContact |
| ASN 23 | NTc.Cm11 | GLU 14 | - | HBDonor |
| ASN 23 | NTc.Cm11 | GLU 14 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 13 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 13 | - | VdWContact |
| PHE 24 | NTc.Cm10 | GLU 14 | - | VdWContact |
| PHE 24 | NTc.Cm10 | GLU 17 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | GLU 17 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 22 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 22 | - | PiStacking |
| PHE 24 | NTc.Cm10 | TYR 22 | - | VdWContact |
| GLU 30 | NTc.Cm4 | ARG 190 | - | Anionic |
| THR 31 | NTc.Cm3 | ILE 30 | - | Hydrophobic |
| LEU 34 | CX.1 | ILE 185 | 45.51x51 | Hydrophobic |
| LEU 34 | CX.1 | ILE 185 | 45.51x51 | VdWContact |
| LEU 34 | CX.1 | PRO 186 | 45.52x52 | Hydrophobic |
| LEU 34 | CX.1 | PRO 186 | 45.52x52 | VdWContact |
| VAL 41 | cxb1.8 | ILE 30 | - | Hydrophobic |
| VAL 41 | cxb1.8 | ILE 30 | - | VdWContact |
| THR 44 | cxb1.14 | TYR 24 | - | HBDonor |
| THR 44 | cxb1.14 | TYR 24 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 24 | - | VdWContact |
| LYS 45 | cxb1.15 | GLU 14 | - | Cationic |
| ARG 46 | cxb1.16 | ASN 16 | - | HBDonor |
| ARG 46 | cxb1.16 | ASN 16 | - | VdWContact |
| ARG 46 | cxb1.16 | GLU 17 | - | HBDonor |
| ARG 46 | cxb1.16 | GLU 17 | - | Hydrophobic |
| ARG 46 | cxb1.16 | GLU 17 | - | VdWContact |
| ARG 46 | cxb1.16 | GLY 20 | - | HBDonor |
| ARG 46 | cxb1.16 | GLY 20 | - | VdWContact |
| ARG 46 | cxb1.16 | TYR 24 | - | Hydrophobic |
| ARG 46 | cxb1.16 | TYR 24 | - | VdWContact |
| LYS 48 | B1.2 | TYR 24 | - | Hydrophobic |
| LYS 48 | B1.2 | TYR 24 | - | VdWContact |
| LYS 48 | B1.2 | LEU 29 | - | Hydrophobic |
| GLN 49 | B1.3 | LEU 29 | - | VdWContact |
| GLN 49 | B1.3 | ILE 30 | - | HBAcceptor |
| GLN 49 | B1.3 | ILE 30 | - | Hydrophobic |
| GLN 49 | B1.3 | ILE 30 | - | VdWContact |
| VAL 50 | B1.4 | TYR 24 | - | Hydrophobic |
| VAL 50 | B1.4 | TYR 27 | - | Hydrophobic |
| VAL 50 | B1.4 | TYR 27 | - | VdWContact |
| VAL 50 | B1.4 | LEU 29 | - | Hydrophobic |
| CYS 51 | B1.5 | GLU 28 | - | HBDonor |
| CYS 51 | B1.5 | GLU 28 | - | Hydrophobic |
| CYS 51 | B1.5 | GLU 28 | - | VdWContact |
| CYS 51 | B1.5 | ILE 30 | - | VdWContact |
