Predicted complex interactions
CCL8_HUMAN + ACKR4
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | GLN 172 | 4.60x61 | Hydrophobic |
| GLN 1 | NTc.Cm33 | GLN 172 | 4.60x61 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 176 | 4.64x65 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 176 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | PHE 188 | - | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 204 | 5.42x43 | Cationic |
| GLN 1 | NTc.Cm33 | GLU 204 | 5.42x43 | HBDonor |
| GLN 1 | NTc.Cm33 | GLU 204 | 5.42x43 | VdWContact |
| GLN 1 | NTc.Cm33 | LYS 260 | 6.55x55 | VdWContact |
| PRO 2 | NTc.Cm32 | SER 116 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 119 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 119 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm32 | THR 120 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm32 | GLN 172 | 4.60x61 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 176 | 4.64x65 | HBAcceptor |
| PRO 2 | NTc.Cm32 | TYR 176 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 176 | 4.64x65 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 176 | 4.64x65 | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 176 | 4.64x65 | VdWContact |
| ASP 3 | NTc.Cm31 | PRO 186 | 45.52x52 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 263 | 6.58x58 | Anionic |
| SER 4 | NTc.Cm30 | TRP 97 | 2.60x60 | VdWContact |
| SER 4 | NTc.Cm30 | CYS 184 | 45.50x50 | HBDonor |
| SER 4 | NTc.Cm30 | CYS 184 | 45.50x50 | VdWContact |
| SER 4 | NTc.Cm30 | ILE 185 | 45.51x51 | HBDonor |
| SER 4 | NTc.Cm30 | ILE 185 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm29 | ARG 263 | 6.58x58 | VdWContact |
| VAL 5 | NTc.Cm29 | ILE 285 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm29 | ILE 285 | 7.35x34 | VdWContact |
| VAL 5 | NTc.Cm29 | GLN 286 | 7.36x35 | Hydrophobic |
| SER 6 | NTc.Cm28 | LEU 44 | 1.35x35 | VdWContact |
| SER 6 | NTc.Cm28 | GLN 286 | 7.36x35 | VdWContact |
| ILE 7 | NTc.Cm27 | ARG 37 | 1.28x28 | Hydrophobic |
| ILE 7 | NTc.Cm27 | ARG 183 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | ARG 183 | - | VdWContact |
| PRO 8 | NTc.Cm26 | LYS 33 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 33 | - | VdWContact |
| PRO 8 | NTc.Cm26 | VAL 36 | 1.27x27 | Hydrophobic |
| PRO 8 | NTc.Cm26 | VAL 36 | 1.27x27 | VdWContact |
| PRO 8 | NTc.Cm26 | ARG 37 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 37 | 1.28x28 | VdWContact |
| ILE 9 | NTc.Cm25 | LYS 33 | - | HBAcceptor |
| ILE 9 | NTc.Cm25 | LYS 33 | - | VdWContact |
| ILE 9 | NTc.Cm25 | ILE 185 | 45.51x51 | Hydrophobic |
| THR 10 | NTc.Cm24 | ILE 30 | - | Hydrophobic |
| CYS 11 | NTc.Cm23 | CYS 31 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 31 | - | VdWContact |
| CYS 12 | NTc.Cm22 | LEU 29 | - | VdWContact |
| PHE 13 | NTc.Cm21 | LEU 29 | - | HBDonor |
| PHE 13 | NTc.Cm21 | LEU 29 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 31 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 31 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ILE 272 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ILE 272 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 275 | 7.25x24 | Hydrophobic |
| PHE 13 | NTc.Cm21 | SER 278 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | LEU 29 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | LEU 29 | - | VdWContact |
| VAL 15 | NTc.Cm19 | LEU 29 | - | VdWContact |
| ILE 16 | NTc.Cm18 | TYR 22 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | TYR 27 | - | VdWContact |
| ILE 16 | NTc.Cm18 | LEU 29 | - | Hydrophobic |
| LYS 19 | NTc.Cm15 | GLU 14 | - | Cationic |
| LYS 19 | NTc.Cm15 | GLU 14 | - | HBDonor |
| LYS 19 | NTc.Cm15 | GLU 14 | - | VdWContact |
| LYS 19 | NTc.Cm15 | TYR 22 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 22 | - | Hydrophobic |
| GLN 23 | NTc.Cm11 | MET 18 | - | Hydrophobic |
| GLN 23 | NTc.Cm11 | MET 18 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLU 17 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 17 | - | VdWContact |
| ARG 24 | NTc.Cm10 | MET 18 | - | HBDonor |
| ARG 24 | NTc.Cm10 | MET 18 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | MET 18 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 22 | - | VdWContact |
| ASN 33 | NTc.Cm1 | ILE 185 | 45.51x51 | VdWContact |
| ILE 34 | CX.1 | PHE 188 | - | Hydrophobic |
| ILE 34 | CX.1 | LYS 197 | 5.35x36 | Hydrophobic |
| ILE 34 | CX.1 | LYS 197 | 5.35x36 | VdWContact |
| ILE 34 | CX.1 | ILE 267 | 6.62x62 | Hydrophobic |
| ILE 34 | CX.1 | ILE 267 | 6.62x62 | VdWContact |
| GLN 35 | CX.5 | ARG 263 | 6.58x58 | VdWContact |
| GLU 39 | cxb1.6 | ARG 190 | - | Anionic |
| ILE 42 | cxb1.10 | ILE 30 | - | Hydrophobic |
| ILE 42 | cxb1.10 | ILE 30 | - | VdWContact |
| THR 45 | cxb1.15 | TYR 24 | - | Hydrophobic |
| LYS 49 | B1.3 | TYR 24 | - | Hydrophobic |
| LYS 49 | B1.3 | TYR 24 | - | VdWContact |
| GLU 50 | B1.4 | ILE 30 | - | Hydrophobic |
| GLU 50 | B1.4 | ILE 30 | - | VdWContact |
| VAL 51 | B1.5 | TYR 24 | - | Hydrophobic |
| VAL 51 | B1.5 | TYR 27 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 29 | - | Hydrophobic |
| CYS 52 | B1.6 | LEU 29 | - | Hydrophobic |
| CYS 52 | B1.6 | LEU 29 | - | VdWContact |
| CYS 52 | B1.6 | ILE 30 | - | VdWContact |
