Predicted complex interactions
CXCL1_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | GLU 204 | 5.42x43 | Cationic |
| ALA 1 | NTc.Cm42 | TYR 256 | 6.51x51 | HBDonor |
| ALA 1 | NTc.Cm42 | TYR 256 | 6.51x51 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 256 | 6.51x51 | VdWContact |
| ALA 1 | NTc.Cm42 | LYS 260 | 6.55x55 | Hydrophobic |
| ALA 1 | NTc.Cm42 | ILE 285 | 7.35x34 | Hydrophobic |
| ALA 1 | NTc.Cm42 | GLU 289 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm42 | GLU 289 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm41 | ARG 263 | 6.58x58 | HBAcceptor |
| SER 2 | NTc.Cm41 | GLU 289 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm40 | LEU 44 | 1.35x35 | Hydrophobic |
| VAL 3 | NTc.Cm40 | LEU 48 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TRP 97 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TYR 119 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm40 | TYR 119 | 3.32x32 | VdWContact |
| VAL 3 | NTc.Cm40 | GLU 289 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm39 | ASN 100 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | ARG 183 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | ARG 183 | - | VdWContact |
| GLU 6 | NTc.Cm37 | ILE 185 | 45.51x51 | Hydrophobic |
| GLU 6 | NTc.Cm37 | ILE 185 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm36 | LYS 33 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | LYS 33 | - | VdWContact |
| LEU 7 | NTc.Cm36 | VAL 36 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm36 | VAL 36 | 1.27x27 | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 37 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 37 | 1.28x28 | VdWContact |
| LEU 7 | NTc.Cm36 | ASP 282 | 7.32x31 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ASP 282 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm35 | LYS 33 | - | HBAcceptor |
| ARG 8 | NTc.Cm35 | LYS 33 | - | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 266 | 6.61x61 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 266 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 266 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | ILE 272 | - | HBDonor |
| ARG 8 | NTc.Cm35 | ILE 272 | - | VdWContact |
| ARG 8 | NTc.Cm35 | SER 278 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 282 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 282 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | ILE 30 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | ILE 30 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 31 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 31 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 31 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | THR 273 | - | VdWContact |
| LEU 12 | NTc.Cm31 | SER 274 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 275 | 7.25x24 | VdWContact |
| GLN 13 | NTc.Cm30 | GLU 28 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | GLU 28 | - | VdWContact |
| LEU 15 | NTc.Cm28 | TYR 24 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 27 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | TYR 27 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 24 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 24 | - | VdWContact |
| HIS 19 | NTc.Cm24 | TYR 13 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | TYR 13 | - | VdWContact |
| HIS 19 | NTc.Cm24 | MET 18 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | MET 18 | - | VdWContact |
| HIS 19 | NTc.Cm24 | TYR 24 | - | HBDonor |
| HIS 19 | NTc.Cm24 | TYR 24 | - | VdWContact |
| PRO 20 | NTc.Cm23 | TYR 13 | - | Hydrophobic |
| PRO 20 | NTc.Cm23 | TYR 13 | - | VdWContact |
| LYS 21 | NTc.Cm22 | GLU 15 | - | Cationic |
| LYS 21 | NTc.Cm22 | GLU 15 | - | HBDonor |
| LYS 21 | NTc.Cm22 | GLU 15 | - | VdWContact |
| PRO 31 | NTc.Cm12 | PHE 188 | - | HBAcceptor |
| PRO 31 | NTc.Cm12 | PHE 188 | - | VdWContact |
| PRO 31 | NTc.Cm12 | ARG 190 | - | Hydrophobic |
| GLY 32 | NTc.Cm11 | PRO 186 | 45.52x52 | VdWContact |
| GLY 32 | NTc.Cm11 | PHE 188 | - | VdWContact |
| PRO 33 | NTc.Cm10 | PRO 186 | 45.52x52 | Hydrophobic |
| PRO 33 | NTc.Cm10 | PRO 186 | 45.52x52 | VdWContact |
| PRO 33 | NTc.Cm10 | PHE 188 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | PHE 188 | - | VdWContact |
| PRO 33 | NTc.Cm10 | ILE 267 | 6.62x62 | VdWContact |
| HIS 34 | NTc.Cm9 | ARG 263 | 6.58x58 | VdWContact |
| ALA 36 | NTc.Cm7 | THR 194 | - | Hydrophobic |
| ALA 36 | NTc.Cm7 | LYS 197 | 5.35x36 | HBAcceptor |
| ALA 36 | NTc.Cm7 | LYS 197 | 5.35x36 | Hydrophobic |
| ALA 36 | NTc.Cm7 | LYS 197 | 5.35x36 | VdWContact |
| ALA 36 | NTc.Cm7 | ILE 267 | 6.62x62 | Hydrophobic |
| ALA 36 | NTc.Cm7 | ILE 267 | 6.62x62 | VdWContact |
| THR 38 | NTc.Cm5 | ARG 190 | - | HBAcceptor |
| THR 38 | NTc.Cm5 | ARG 190 | - | VdWContact |
| ILE 41 | NTc.Cm2 | ILE 30 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | ILE 30 | - | VdWContact |
| LEU 44 | CX.4 | TYR 24 | - | Hydrophobic |
| ARG 48 | cxb1.5 | ASP 23 | - | Cationic |
| ARG 48 | cxb1.5 | SER 25 | - | VdWContact |
| ARG 48 | cxb1.5 | LEU 29 | - | Hydrophobic |
| LYS 49 | cxb1.6 | LEU 29 | - | VdWContact |
| LYS 49 | cxb1.6 | ILE 30 | - | HBAcceptor |
| LYS 49 | cxb1.6 | ILE 30 | - | Hydrophobic |
| LYS 49 | cxb1.6 | ILE 30 | - | VdWContact |
| ILE 58 | B1.3 | TYR 13 | - | Hydrophobic |
| ILE 58 | B1.3 | TYR 13 | - | VdWContact |
