Predicted complex interactions
CCL25_HUMAN + ACKR1
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR1 View partner entry
- Partner description
- UniProt: Q16570; Gene: ackr1_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | PHE 65 | 1.39x39 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 290 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 194 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | THR 196 | 45.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm27 | THR 196 | 45.51x51 | VdWContact |
| PHE 4 | NTc.Cm26 | SER 53 | - | VdWContact |
| PHE 4 | NTc.Cm26 | ASN 55 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 283 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 283 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | LEU 286 | 7.35x34 | Hydrophobic |
| GLU 5 | NTc.Cm25 | SER 53 | - | VdWContact |
| ASP 6 | NTc.Cm24 | PRO 50 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | CYS 51 | - | VdWContact |
| ASP 6 | NTc.Cm24 | HIS 52 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | HIS 52 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 51 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 51 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 51 | - | VdWContact |
| CYS 7 | NTc.Cm23 | GLN 279 | 7.28x27 | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 51 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 276 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 276 | 7.25x24 | VdWContact |
| LEU 9 | NTc.Cm21 | GLN 279 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLN 279 | 7.28x27 | VdWContact |
| HIS 12 | NTc.Cm18 | ALA 47 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ALA 47 | - | VdWContact |
| HIS 12 | NTc.Cm18 | ALA 48 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ALA 48 | - | VdWContact |
| ILE 15 | NTc.Cm15 | ALA 48 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 41 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | LEU 45 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | LEU 45 | - | VdWContact |
| ARG 21 | NTc.Cm9 | ASP 34 | - | Cationic |
| ARG 21 | NTc.Cm9 | ASP 34 | - | HBDonor |
| ARG 21 | NTc.Cm9 | ASP 34 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 34 | - | HBDonor |
| ARG 22 | NTc.Cm8 | ASP 34 | - | VdWContact |
| ARG 22 | NTc.Cm8 | SER 35 | - | HBDonor |
| ARG 22 | NTc.Cm8 | SER 35 | - | VdWContact |
| ARG 22 | NTc.Cm8 | PHE 36 | - | CationPi |
| ARG 22 | NTc.Cm8 | PHE 36 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | PHE 36 | - | VdWContact |
| TRP 24 | NTc.Cm6 | TRP 26 | - | Hydrophobic |
| VAL 31 | CX.5 | LYS 269 | 6.64x64 | VdWContact |
| GLY 33 | cxb1.2 | ARG 267 | 6.62x62 | VdWContact |
| ASN 36 | cxb1.8 | VAL 266 | 6.61x61 | HBDonor |
| ASN 36 | cxb1.8 | VAL 266 | 6.61x61 | VdWContact |
| ASN 36 | cxb1.8 | LYS 269 | 6.64x64 | VdWContact |
| LEU 44 | B1.3 | LEU 45 | - | Hydrophobic |
| LYS 46 | B1.5 | PHE 36 | - | Hydrophobic |
| ARG 47 | B1.6 | GLU 9 | - | Cationic |
| ARG 47 | B1.6 | GLU 9 | - | HBDonor |
| ARG 47 | B1.6 | GLU 9 | - | VdWContact |
| ARG 49 | b1b2.1 | GLU 46 | - | Cationic |
| ARG 49 | b1b2.1 | GLU 46 | - | HBDonor |
| ARG 49 | b1b2.1 | GLU 46 | - | VdWContact |
| LYS 50 | b1b2.2 | ALA 49 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 50 | - | Hydrophobic |
| VAL 51 | b1b2.3 | LEU 45 | - | Hydrophobic |
| VAL 51 | b1b2.3 | ALA 48 | - | Hydrophobic |
| VAL 51 | b1b2.3 | ALA 48 | - | VdWContact |
| CYS 52 | b1b2.4 | ALA 48 | - | HBDonor |
| CYS 52 | b1b2.4 | ALA 48 | - | VdWContact |
| CYS 52 | b1b2.4 | PRO 50 | - | VdWContact |
| ARG 70 | b2b3.4 | TRP 26 | - | CationPi |
| ARG 70 | b2b3.4 | TRP 26 | - | Hydrophobic |
| ARG 70 | b2b3.4 | TRP 26 | - | VdWContact |
| ARG 70 | b2b3.4 | TYR 30 | - | CationPi |
| ARG 70 | b2b3.4 | TYR 30 | - | Hydrophobic |
| ARG 70 | b2b3.4 | TYR 30 | - | VdWContact |
| PHE 74 | B3.2 | PHE 22 | - | Hydrophobic |
| PHE 74 | B3.2 | TRP 26 | - | Hydrophobic |
