Predicted complex interactions
CXCL17_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 155
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 20 | NTc.Cm30 | TYR 13 | - | Hydrophobic |
| ARG 20 | NTc.Cm30 | TYR 13 | - | VdWContact |
| ARG 20 | NTc.Cm30 | GLU 14 | - | HBDonor |
| ARG 20 | NTc.Cm30 | GLU 14 | - | VdWContact |
| TRP 21 | NTc.Cm29 | TYR 27 | - | HBDonor |
| TRP 21 | NTc.Cm29 | TYR 27 | - | Hydrophobic |
| TRP 21 | NTc.Cm29 | TYR 27 | - | VdWContact |
| GLN 23 | NTc.Cm27 | TYR 11 | - | VdWContact |
| GLN 23 | NTc.Cm27 | TYR 13 | - | Hydrophobic |
| GLN 23 | NTc.Cm27 | TYR 13 | - | VdWContact |
| GLU 28 | NTc.Cm22 | ARG 190 | - | Anionic |
| GLU 28 | NTc.Cm22 | ARG 190 | - | VdWContact |
| LYS 32 | NTc.Cm18 | ASN 179 | - | HBDonor |
| LYS 32 | NTc.Cm18 | ASN 179 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | ASN 179 | - | VdWContact |
| LYS 32 | NTc.Cm18 | ASP 180 | - | Cationic |
| LYS 32 | NTc.Cm18 | ASP 180 | - | VdWContact |
| LYS 32 | NTc.Cm18 | ILE 185 | 45.51x51 | Hydrophobic |
| LYS 32 | NTc.Cm18 | ILE 185 | 45.51x51 | VdWContact |
| LYS 32 | NTc.Cm18 | ILE 187 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | ILE 187 | - | VdWContact |
| ASP 33 | NTc.Cm17 | ASN 179 | - | VdWContact |
| ASP 33 | NTc.Cm17 | ASN 181 | - | HBAcceptor |
| ASP 33 | NTc.Cm17 | ASN 181 | - | VdWContact |
| TRP 34 | NTc.Cm16 | CYS 31 | - | HBDonor |
| TRP 34 | NTc.Cm16 | CYS 31 | - | Hydrophobic |
| TRP 34 | NTc.Cm16 | CYS 31 | - | VdWContact |
| TRP 34 | NTc.Cm16 | LYS 33 | - | Hydrophobic |
| TRP 34 | NTc.Cm16 | LYS 33 | - | VdWContact |
| TRP 34 | NTc.Cm16 | ARG 37 | 1.28x28 | VdWContact |
| TRP 34 | NTc.Cm16 | SER 278 | 7.28x27 | VdWContact |
| PHE 35 | NTc.Cm15 | ARG 37 | 1.28x28 | VdWContact |
| PHE 35 | NTc.Cm15 | ARG 183 | - | HBAcceptor |
| PHE 35 | NTc.Cm15 | ARG 183 | - | VdWContact |
| PHE 35 | NTc.Cm15 | ARG 263 | 6.58x58 | VdWContact |
| PHE 35 | NTc.Cm15 | ASP 282 | 7.32x31 | Hydrophobic |
| PHE 35 | NTc.Cm15 | ASP 282 | 7.32x31 | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 37 | 1.28x28 | HBAcceptor |
| LEU 36 | NTc.Cm14 | ARG 37 | 1.28x28 | VdWContact |
| LEU 36 | NTc.Cm14 | ASN 179 | - | Hydrophobic |
| LEU 36 | NTc.Cm14 | ASN 179 | - | VdWContact |
| LEU 36 | NTc.Cm14 | ASN 181 | - | Hydrophobic |
| LEU 36 | NTc.Cm14 | ASN 181 | - | VdWContact |
| LEU 36 | NTc.Cm14 | ARG 183 | - | Hydrophobic |
| LEU 36 | NTc.Cm14 | ARG 183 | - | VdWContact |
| ARG 37 | NTc.Cm13 | LYS 33 | - | HBAcceptor |
| ARG 37 | NTc.Cm13 | LYS 33 | - | VdWContact |
| ARG 37 | NTc.Cm13 | ARG 37 | 1.28x28 | HBAcceptor |
| ARG 37 | NTc.Cm13 | ARG 37 | 1.28x28 | VdWContact |
| ALA 38 | NTc.Cm12 | LYS 33 | - | HBDonor |
| ALA 38 | NTc.Cm12 | LYS 33 | - | VdWContact |
| ALA 38 | NTc.Cm12 | GLU 34 | - | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 37 | 1.28x28 | Hydrophobic |
| ALA 38 | NTc.Cm12 | ARG 37 | 1.28x28 | VdWContact |
| PRO 39 | NTc.Cm11 | ILE 32 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | ILE 32 | - | VdWContact |
| PRO 39 | NTc.Cm11 | GLU 34 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | GLU 34 | - | VdWContact |
| ARG 40 | NTc.Cm10 | ASN 181 | - | VdWContact |
| GLN 53 | cxb1.1 | TYR 24 | - | VdWContact |
| PRO 55 | cxb1.5 | ILE 30 | - | VdWContact |
| CYS 56 | cxb1.6 | ILE 30 | - | Hydrophobic |
| CYS 56 | cxb1.6 | ILE 30 | - | VdWContact |
| ASP 57 | cxb1.7 | ILE 30 | - | VdWContact |
| ASP 57 | cxb1.7 | ILE 32 | - | VdWContact |
| HIS 58 | cxb1.10 | TYR 27 | - | Hydrophobic |
| HIS 58 | cxb1.10 | LEU 29 | - | VdWContact |
| HIS 58 | cxb1.10 | ILE 30 | - | Hydrophobic |
| HIS 58 | cxb1.10 | ILE 30 | - | VdWContact |
| PHE 59 | cxb1.11 | LEU 29 | - | Hydrophobic |
| PHE 59 | cxb1.11 | LEU 29 | - | VdWContact |
| PHE 59 | cxb1.11 | ILE 30 | - | HBAcceptor |
| PHE 59 | cxb1.11 | ILE 30 | - | HBDonor |
| PHE 59 | cxb1.11 | ILE 30 | - | VdWContact |
| PHE 59 | cxb1.11 | CYS 31 | - | VdWContact |
| PHE 59 | cxb1.11 | CYS 275 | 7.25x24 | Hydrophobic |
| PHE 59 | cxb1.11 | CYS 275 | 7.25x24 | VdWContact |
| LYS 60 | cxb1.14 | ILE 32 | - | Hydrophobic |
| LYS 60 | cxb1.14 | ILE 32 | - | VdWContact |
| LYS 60 | cxb1.14 | ASP 35 | - | Cationic |
| LYS 60 | cxb1.14 | ASP 35 | - | HBDonor |
| LYS 60 | cxb1.14 | ASP 35 | - | VdWContact |
| LYS 60 | cxb1.14 | LYS 279 | 7.29x28 | VdWContact |
| ASN 62 | cxb1.16 | SER 25 | - | HBDonor |
| ASN 62 | cxb1.16 | SER 25 | - | VdWContact |
| ASN 62 | cxb1.16 | LEU 29 | - | Hydrophobic |
| ASN 62 | cxb1.16 | LEU 29 | - | VdWContact |
| VAL 63 | B1.2 | LEU 29 | - | Hydrophobic |
| ARG 73 | b1b2.7 | ASP 23 | - | Cationic |
| ARG 73 | b1b2.7 | ASP 23 | - | HBDonor |
| ARG 73 | b1b2.7 | ASP 23 | - | VdWContact |
| ARG 73 | b1b2.7 | SER 25 | - | VdWContact |
| ARG 73 | b1b2.7 | GLN 26 | - | Hydrophobic |
| ARG 73 | b1b2.7 | GLN 26 | - | VdWContact |
| LYS 74 | b1b2.8 | GLN 26 | - | VdWContact |
| ASN 76 | b1b2.10 | GLN 26 | - | HBDonor |
| ASN 76 | b1b2.10 | GLN 26 | - | Hydrophobic |
| ASN 76 | b1b2.10 | GLN 26 | - | VdWContact |
| ASN 76 | b1b2.10 | TYR 27 | - | HBDonor |
| ASN 76 | b1b2.10 | TYR 27 | - | VdWContact |
| HIS 78 | b1b2.13 | TYR 27 | - | Hydrophobic |
| HIS 78 | b1b2.13 | TYR 27 | - | PiStacking |
| HIS 78 | b1b2.13 | TYR 27 | - | VdWContact |
| HIS 78 | b1b2.13 | GLU 28 | - | VdWContact |
| SER 79 | b1b2.14 | GLU 28 | - | HBDonor |
| SER 79 | b1b2.14 | GLU 28 | - | VdWContact |
| CYS 82 | b1b2.18 | LEU 29 | - | VdWContact |
| CYS 82 | b1b2.18 | ILE 30 | - | Hydrophobic |
| CYS 82 | b1b2.18 | ILE 30 | - | VdWContact |
| GLN 83 | b1b2.19 | GLU 28 | - | HBDonor |
| GLN 83 | b1b2.19 | GLU 28 | - | VdWContact |
| LYS 87 | b1b2.23 | ILE 267 | 6.62x62 | VdWContact |
| LYS 87 | b1b2.23 | ILE 268 | 6.63x63 | HBDonor |
| LYS 87 | b1b2.23 | ILE 268 | 6.63x63 | VdWContact |
| LYS 87 | b1b2.23 | SER 270 | - | HBDonor |
| LYS 87 | b1b2.23 | SER 270 | - | VdWContact |
| GLN 90 | B2.1 | ASP 266 | 6.61x61 | HBDonor |
| GLN 90 | B2.1 | ASP 266 | 6.61x61 | VdWContact |
| GLN 90 | B2.1 | ILE 272 | - | VdWContact |
| LEU 91 | B2.2 | THR 194 | - | Hydrophobic |
| LEU 91 | B2.2 | THR 194 | - | VdWContact |
| LEU 91 | B2.2 | LYS 197 | 5.35x36 | Hydrophobic |
| LEU 91 | B2.2 | LYS 197 | 5.35x36 | VdWContact |
| LEU 91 | B2.2 | ILE 267 | 6.62x62 | Hydrophobic |
| LEU 91 | B2.2 | ILE 267 | 6.62x62 | VdWContact |
| ARG 92 | B2.3 | PRO 186 | 45.52x52 | VdWContact |
| ARG 92 | B2.3 | ILE 187 | - | Hydrophobic |
| ARG 92 | B2.3 | ILE 187 | - | VdWContact |
| ARG 92 | B2.3 | PHE 188 | - | VdWContact |
| PHE 94 | B2.5 | GLN 201 | 5.39x40 | VdWContact |
| PHE 94 | B2.5 | ARG 263 | 6.58x58 | HBAcceptor |
| PHE 94 | B2.5 | ARG 263 | 6.58x58 | Hydrophobic |
| PHE 94 | B2.5 | ARG 263 | 6.58x58 | PiCation |
| PHE 94 | B2.5 | ARG 263 | 6.58x58 | VdWContact |
| PHE 94 | B2.5 | ILE 267 | 6.62x62 | Hydrophobic |
| PHE 94 | B2.5 | ILE 267 | 6.62x62 | VdWContact |
| ALA 95 | B2.6 | ILE 185 | 45.51x51 | Hydrophobic |
| ALA 95 | B2.6 | ILE 185 | 45.51x51 | VdWContact |
| ALA 95 | B2.6 | PRO 186 | 45.52x52 | Hydrophobic |
| ALA 95 | B2.6 | PRO 186 | 45.52x52 | VdWContact |
| LEU 96 | b2b3.2 | ARG 263 | 6.58x58 | HBAcceptor |
| LEU 96 | b2b3.2 | ARG 263 | 6.58x58 | VdWContact |
| LEU 96 | b2b3.2 | ASP 282 | 7.32x31 | Hydrophobic |
| LEU 96 | b2b3.2 | ILE 285 | 7.35x34 | Hydrophobic |
| LEU 96 | b2b3.2 | ILE 285 | 7.35x34 | VdWContact |
| LEU 96 | b2b3.2 | GLN 286 | 7.36x35 | Hydrophobic |
| LEU 96 | b2b3.2 | GLN 286 | 7.36x35 | VdWContact |
| PRO 97 | b2b3.3 | TRP 97 | 2.60x60 | Hydrophobic |
| PRO 97 | b2b3.3 | CYS 184 | 45.50x50 | VdWContact |
| LEU 98 | b2b3.4 | TRP 97 | 2.60x60 | VdWContact |
| LEU 98 | b2b3.4 | TYR 119 | 3.32x32 | Hydrophobic |
| LEU 98 | b2b3.4 | TYR 119 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | GLU 289 | 7.39x38 | Hydrophobic |
| LEU 98 | b2b3.4 | GLU 289 | 7.39x38 | VdWContact |
| LEU 98 | b2b3.4 | LEU 293 | 7.43x42 | Hydrophobic |
