Predicted complex interactions
CXCL4_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 3 | NTc.Cm38 | ARG 37 | 1.28x28 | Anionic |
| GLU 3 | NTc.Cm38 | ARG 37 | 1.28x28 | HBAcceptor |
| GLU 3 | NTc.Cm38 | ARG 37 | 1.28x28 | VdWContact |
| GLU 4 | NTc.Cm37 | ASN 179 | - | HBAcceptor |
| GLU 4 | NTc.Cm37 | ASN 179 | - | VdWContact |
| GLU 4 | NTc.Cm37 | ASN 181 | - | HBAcceptor |
| GLU 4 | NTc.Cm37 | ASN 181 | - | VdWContact |
| ASP 5 | NTc.Cm36 | ARG 37 | 1.28x28 | Anionic |
| ASP 5 | NTc.Cm36 | ARG 37 | 1.28x28 | VdWContact |
| ASP 5 | NTc.Cm36 | ARG 183 | - | Anionic |
| ASP 5 | NTc.Cm36 | ARG 183 | - | HBAcceptor |
| ASP 5 | NTc.Cm36 | ARG 183 | - | VdWContact |
| GLY 6 | NTc.Cm35 | ILE 185 | 45.51x51 | VdWContact |
| ASP 7 | NTc.Cm34 | ASN 100 | 2.63x63 | HBAcceptor |
| ASP 7 | NTc.Cm34 | ASN 100 | 2.63x63 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 183 | - | HBAcceptor |
| ASP 7 | NTc.Cm34 | ARG 183 | - | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 33 | - | Hydrophobic |
| LEU 8 | NTc.Cm33 | VAL 36 | 1.27x27 | Hydrophobic |
| LEU 8 | NTc.Cm33 | VAL 36 | 1.27x27 | VdWContact |
| LEU 8 | NTc.Cm33 | ARG 37 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ASP 282 | 7.32x31 | Hydrophobic |
| GLN 9 | NTc.Cm32 | LYS 33 | - | HBAcceptor |
| GLN 9 | NTc.Cm32 | LYS 33 | - | VdWContact |
| GLN 9 | NTc.Cm32 | ARG 263 | 6.58x58 | VdWContact |
| GLN 9 | NTc.Cm32 | ILE 272 | - | VdWContact |
| GLN 9 | NTc.Cm32 | SER 278 | 7.28x27 | HBAcceptor |
| GLN 9 | NTc.Cm32 | SER 278 | 7.28x27 | HBDonor |
| GLN 9 | NTc.Cm32 | SER 278 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | MET 281 | 7.31x30 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 282 | 7.32x31 | HBDonor |
| GLN 9 | NTc.Cm32 | ASP 282 | 7.32x31 | VdWContact |
| LEU 11 | NTc.Cm30 | ILE 30 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | CYS 31 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 31 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 31 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | CYS 31 | - | VdWContact |
| VAL 13 | NTc.Cm28 | ILE 272 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | ILE 272 | - | VdWContact |
| VAL 13 | NTc.Cm28 | THR 273 | - | VdWContact |
| VAL 13 | NTc.Cm28 | SER 274 | 7.24x23 | VdWContact |
| LYS 14 | NTc.Cm27 | GLU 28 | - | Cationic |
| LYS 14 | NTc.Cm27 | GLU 28 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | GLU 28 | - | VdWContact |
| LYS 14 | NTc.Cm27 | THR 273 | - | VdWContact |
| THR 16 | NTc.Cm25 | TYR 27 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | GLU 28 | - | HBAcceptor |
| THR 16 | NTc.Cm25 | GLU 28 | - | VdWContact |
| VAL 19 | NTc.Cm22 | TYR 27 | - | Hydrophobic |
| VAL 19 | NTc.Cm22 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm21 | GLU 17 | - | Cationic |
| ARG 20 | NTc.Cm21 | GLU 17 | - | HBDonor |
| ARG 20 | NTc.Cm21 | GLU 17 | - | VdWContact |
| ARG 22 | NTc.Cm19 | GLU 14 | - | VdWContact |
| ARG 22 | NTc.Cm19 | GLU 17 | - | Cationic |
| ARG 22 | NTc.Cm19 | GLU 17 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 22 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 22 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 24 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | ILE 187 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | ILE 187 | - | VdWContact |
| ALA 32 | NTc.Cm9 | ILE 187 | - | VdWContact |
| ALA 32 | NTc.Cm9 | PHE 188 | - | HBAcceptor |
| ALA 32 | NTc.Cm9 | PHE 188 | - | VdWContact |
| GLY 33 | NTc.Cm8 | PRO 186 | 45.52x52 | VdWContact |
| GLY 33 | NTc.Cm8 | PHE 188 | - | VdWContact |
| PRO 34 | NTc.Cm7 | PRO 186 | 45.52x52 | Hydrophobic |
| PRO 34 | NTc.Cm7 | PRO 186 | 45.52x52 | VdWContact |
| HIS 35 | NTc.Cm6 | ILE 185 | 45.51x51 | Hydrophobic |
| HIS 35 | NTc.Cm6 | ARG 263 | 6.58x58 | VdWContact |
| PRO 37 | NTc.Cm4 | LYS 197 | 5.35x36 | HBAcceptor |
| PRO 37 | NTc.Cm4 | LYS 197 | 5.35x36 | Hydrophobic |
| PRO 37 | NTc.Cm4 | LYS 197 | 5.35x36 | VdWContact |
| PRO 37 | NTc.Cm4 | ILE 267 | 6.62x62 | Hydrophobic |
| PRO 37 | NTc.Cm4 | ILE 267 | 6.62x62 | VdWContact |
| ILE 42 | CX.4 | ILE 30 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 24 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 24 | - | VdWContact |
| LEU 45 | cxb1.2 | TYR 27 | - | Hydrophobic |
| ASN 47 | cxb1.6 | TYR 24 | - | Hydrophobic |
| ASN 47 | cxb1.6 | TYR 24 | - | VdWContact |
| ARG 49 | cxb1.10 | LEU 29 | - | Hydrophobic |
| ARG 49 | cxb1.10 | LEU 29 | - | VdWContact |
| LYS 50 | cxb1.11 | LEU 29 | - | VdWContact |
| LYS 50 | cxb1.11 | ILE 30 | - | HBAcceptor |
| LYS 50 | cxb1.11 | ILE 30 | - | Hydrophobic |
| LYS 50 | cxb1.11 | ILE 30 | - | VdWContact |
| ILE 51 | cxb1.14 | TYR 27 | - | Hydrophobic |
| ILE 51 | cxb1.14 | LEU 29 | - | Hydrophobic |
| ILE 51 | cxb1.14 | LEU 29 | - | VdWContact |
| CYS 52 | cxb1.15 | GLU 28 | - | HBDonor |
| CYS 52 | cxb1.15 | GLU 28 | - | VdWContact |
| CYS 52 | cxb1.15 | ILE 30 | - | VdWContact |
| LEU 55 | B1.2 | ARG 190 | - | HBAcceptor |
| LEU 55 | B1.2 | ARG 190 | - | VdWContact |
| GLN 56 | B1.3 | ARG 190 | - | HBAcceptor |
| GLN 56 | B1.3 | ARG 190 | - | VdWContact |
