Predicted complex interactions
CXCL5_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 118
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | TYR 119 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm48 | TYR 176 | 4.64x65 | VdWContact |
| ALA 1 | NTc.Cm48 | GLU 204 | 5.42x43 | Cationic |
| ALA 1 | NTc.Cm48 | GLU 289 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | LEU 44 | 1.35x35 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 97 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 119 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 119 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | GLU 289 | 7.39x38 | Hydrophobic |
| PRO 3 | NTc.Cm46 | GLU 289 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | LEU 293 | 7.43x42 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TRP 97 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TRP 97 | 2.60x60 | VdWContact |
| ALA 4 | NTc.Cm45 | ASN 100 | 2.63x63 | Hydrophobic |
| ALA 4 | NTc.Cm45 | ASN 100 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 176 | 4.64x65 | Hydrophobic |
| ALA 6 | NTc.Cm43 | ILE 285 | 7.35x34 | Hydrophobic |
| ALA 6 | NTc.Cm43 | ILE 285 | 7.35x34 | VdWContact |
| ALA 6 | NTc.Cm43 | GLN 286 | 7.36x35 | Hydrophobic |
| VAL 7 | NTc.Cm42 | ALA 40 | 1.31x31 | Hydrophobic |
| VAL 7 | NTc.Cm42 | ALA 40 | 1.31x31 | VdWContact |
| VAL 7 | NTc.Cm42 | LEU 44 | 1.35x35 | Hydrophobic |
| VAL 7 | NTc.Cm42 | LEU 44 | 1.35x35 | VdWContact |
| VAL 7 | NTc.Cm42 | GLN 286 | 7.36x35 | Hydrophobic |
| VAL 7 | NTc.Cm42 | GLN 286 | 7.36x35 | VdWContact |
| LEU 8 | NTc.Cm41 | ARG 37 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ARG 37 | 1.28x28 | VdWContact |
| LEU 8 | NTc.Cm41 | ARG 183 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | ARG 183 | - | VdWContact |
| ARG 9 | NTc.Cm40 | LYS 33 | - | Hydrophobic |
| ARG 9 | NTc.Cm40 | ARG 263 | 6.58x58 | VdWContact |
| ARG 9 | NTc.Cm40 | ASP 282 | 7.32x31 | Cationic |
| ARG 9 | NTc.Cm40 | ASP 282 | 7.32x31 | HBDonor |
| ARG 9 | NTc.Cm40 | ASP 282 | 7.32x31 | Hydrophobic |
| ARG 9 | NTc.Cm40 | ASP 282 | 7.32x31 | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 183 | - | Anionic |
| GLU 10 | NTc.Cm39 | ARG 183 | - | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 183 | - | VdWContact |
| LEU 11 | NTc.Cm38 | ARG 263 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 266 | 6.61x61 | Cationic |
| ARG 12 | NTc.Cm37 | ILE 272 | - | VdWContact |
| ARG 12 | NTc.Cm37 | SER 278 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | MET 281 | 7.31x30 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 282 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 282 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 282 | 7.32x31 | VdWContact |
| VAL 14 | NTc.Cm35 | ILE 30 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | ILE 30 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 31 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 31 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 31 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ILE 272 | - | VdWContact |
| LEU 16 | NTc.Cm33 | THR 273 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 275 | 7.25x24 | VdWContact |
| GLN 17 | NTc.Cm32 | GLU 28 | - | Hydrophobic |
| GLN 17 | NTc.Cm32 | GLU 28 | - | VdWContact |
| THR 19 | NTc.Cm30 | TYR 27 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | TYR 27 | - | VdWContact |
| THR 19 | NTc.Cm30 | GLU 28 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | GLU 28 | - | VdWContact |
| VAL 22 | NTc.Cm27 | TYR 13 | - | VdWContact |
| VAL 22 | NTc.Cm27 | TYR 27 | - | Hydrophobic |
| VAL 22 | NTc.Cm27 | TYR 27 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 13 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 13 | - | PiStacking |
| HIS 23 | NTc.Cm26 | TYR 13 | - | VdWContact |
| HIS 23 | NTc.Cm26 | MET 18 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | MET 18 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 22 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 22 | - | VdWContact |
| PRO 24 | NTc.Cm25 | TYR 13 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | TYR 13 | - | VdWContact |
| LYS 25 | NTc.Cm24 | GLU 15 | - | Cationic |
| LYS 25 | NTc.Cm24 | GLU 15 | - | VdWContact |
| LYS 25 | NTc.Cm24 | MET 18 | - | Hydrophobic |
| LYS 25 | NTc.Cm24 | MET 18 | - | VdWContact |
| MET 26 | NTc.Cm23 | TYR 22 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | TYR 22 | - | VdWContact |
| MET 26 | NTc.Cm23 | TYR 24 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | TYR 24 | - | VdWContact |
| MET 26 | NTc.Cm23 | TYR 27 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | TYR 27 | - | VdWContact |
| ALA 34 | NTc.Cm15 | ARG 190 | - | VdWContact |
| GLY 36 | NTc.Cm13 | LYS 197 | 5.35x36 | HBAcceptor |
| GLY 36 | NTc.Cm13 | LYS 197 | 5.35x36 | VdWContact |
| PRO 37 | NTc.Cm12 | ILE 185 | 45.51x51 | Hydrophobic |
| PRO 37 | NTc.Cm12 | PRO 186 | 45.52x52 | Hydrophobic |
| PRO 37 | NTc.Cm12 | PRO 186 | 45.52x52 | VdWContact |
| PRO 37 | NTc.Cm12 | ILE 187 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | ILE 187 | - | VdWContact |
| PRO 37 | NTc.Cm12 | PHE 188 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | PHE 188 | - | VdWContact |
| GLN 38 | NTc.Cm11 | ILE 185 | 45.51x51 | Hydrophobic |
| GLN 38 | NTc.Cm11 | ILE 185 | 45.51x51 | VdWContact |
| SER 40 | NTc.Cm9 | THR 194 | - | VdWContact |
| LYS 41 | NTc.Cm8 | SER 270 | - | VdWContact |
| VAL 45 | NTc.Cm4 | ILE 30 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | TYR 24 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | TYR 24 | - | VdWContact |
| LEU 48 | NTc.Cm1 | TYR 27 | - | Hydrophobic |
| ASN 50 | CX.4 | TYR 24 | - | Hydrophobic |
| ASN 50 | CX.4 | TYR 24 | - | VdWContact |
| LYS 52 | cxb1.1 | TYR 24 | - | Hydrophobic |
| LYS 52 | cxb1.1 | LEU 29 | - | Hydrophobic |
| LYS 52 | cxb1.1 | LEU 29 | - | VdWContact |
| GLU 53 | cxb1.2 | LEU 29 | - | VdWContact |
| GLU 53 | cxb1.2 | ILE 30 | - | HBAcceptor |
| GLU 53 | cxb1.2 | ILE 30 | - | Hydrophobic |
| GLU 53 | cxb1.2 | ILE 30 | - | VdWContact |
| ILE 54 | cxb1.5 | TYR 27 | - | Hydrophobic |
| ILE 54 | cxb1.5 | TYR 27 | - | VdWContact |
| ILE 54 | cxb1.5 | GLU 28 | - | VdWContact |
| ILE 54 | cxb1.5 | LEU 29 | - | Hydrophobic |
| CYS 55 | cxb1.6 | GLU 28 | - | HBDonor |
| CYS 55 | cxb1.6 | GLU 28 | - | VdWContact |
| CYS 55 | cxb1.6 | ILE 30 | - | VdWContact |
| LYS 65 | B1.4 | ASP 10 | - | Cationic |
