Predicted complex interactions
CXCL6_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 100
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 2 | NTc.Cm47 | HIS 103 | 2.66x66 | VdWContact |
| VAL 3 | NTc.Cm46 | ARG 37 | 1.28x28 | VdWContact |
| VAL 3 | NTc.Cm46 | ARG 183 | - | VdWContact |
| SER 4 | NTc.Cm45 | ARG 37 | 1.28x28 | HBAcceptor |
| SER 4 | NTc.Cm45 | ARG 37 | 1.28x28 | HBDonor |
| SER 4 | NTc.Cm45 | ARG 37 | 1.28x28 | VdWContact |
| SER 4 | NTc.Cm45 | ALA 101 | 2.64x64 | VdWContact |
| ALA 5 | NTc.Cm44 | ASN 100 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm44 | ALA 101 | 2.64x64 | VdWContact |
| VAL 6 | NTc.Cm43 | ALA 40 | 1.31x31 | Hydrophobic |
| VAL 6 | NTc.Cm43 | GLN 286 | 7.36x35 | Hydrophobic |
| VAL 6 | NTc.Cm43 | GLN 286 | 7.36x35 | VdWContact |
| LEU 7 | NTc.Cm42 | LEU 44 | 1.35x35 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 44 | 1.35x35 | VdWContact |
| LEU 7 | NTc.Cm42 | LEU 48 | 1.39x39 | Hydrophobic |
| LEU 7 | NTc.Cm42 | TRP 97 | 2.60x60 | Hydrophobic |
| LEU 7 | NTc.Cm42 | GLU 289 | 7.39x38 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 293 | 7.43x42 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 293 | 7.43x42 | VdWContact |
| THR 8 | NTc.Cm41 | ARG 263 | 6.58x58 | VdWContact |
| THR 8 | NTc.Cm41 | ILE 285 | 7.35x34 | Hydrophobic |
| THR 8 | NTc.Cm41 | GLU 289 | 7.39x38 | HBDonor |
| THR 8 | NTc.Cm41 | GLU 289 | 7.39x38 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 37 | 1.28x28 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 37 | 1.28x28 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 37 | 1.28x28 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 183 | - | Anionic |
| GLU 9 | NTc.Cm40 | ILE 185 | 45.51x51 | Hydrophobic |
| GLU 9 | NTc.Cm40 | ARG 263 | 6.58x58 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 263 | 6.58x58 | VdWContact |
| LEU 10 | NTc.Cm39 | LYS 33 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | VAL 36 | 1.27x27 | Hydrophobic |
| LEU 10 | NTc.Cm39 | ARG 37 | 1.28x28 | Hydrophobic |
| LEU 10 | NTc.Cm39 | ASP 282 | 7.32x31 | Hydrophobic |
| LEU 10 | NTc.Cm39 | ASP 282 | 7.32x31 | VdWContact |
| ARG 11 | NTc.Cm38 | LYS 33 | - | HBAcceptor |
| ARG 11 | NTc.Cm38 | LYS 33 | - | VdWContact |
| ARG 11 | NTc.Cm38 | ARG 263 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 266 | 6.61x61 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 266 | 6.61x61 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 266 | 6.61x61 | VdWContact |
| ARG 11 | NTc.Cm38 | ILE 272 | - | VdWContact |
| ARG 11 | NTc.Cm38 | SER 278 | 7.28x27 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 282 | 7.32x31 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 282 | 7.32x31 | VdWContact |
| CYS 12 | NTc.Cm37 | LYS 33 | - | VdWContact |
| THR 13 | NTc.Cm36 | CYS 31 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 31 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 31 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | ILE 272 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 275 | 7.25x24 | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 275 | 7.25x24 | VdWContact |
| LEU 15 | NTc.Cm34 | SER 278 | 7.28x27 | VdWContact |
| ARG 16 | NTc.Cm33 | GLU 28 | - | Cationic |
| ARG 16 | NTc.Cm33 | GLU 28 | - | HBDonor |
| ARG 16 | NTc.Cm33 | GLU 28 | - | Hydrophobic |
| ARG 16 | NTc.Cm33 | GLU 28 | - | VdWContact |
| THR 18 | NTc.Cm31 | TYR 27 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | TYR 27 | - | VdWContact |
| THR 18 | NTc.Cm31 | GLU 28 | - | HBAcceptor |
| THR 18 | NTc.Cm31 | GLU 28 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 27 | - | VdWContact |
| VAL 21 | NTc.Cm28 | TYR 27 | - | Hydrophobic |
| VAL 21 | NTc.Cm28 | TYR 27 | - | VdWContact |
| ASN 22 | NTc.Cm27 | TYR 22 | - | Hydrophobic |
| ASN 22 | NTc.Cm27 | TYR 22 | - | VdWContact |
| PRO 23 | NTc.Cm26 | TYR 13 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | TYR 13 | - | VdWContact |
| THR 25 | NTc.Cm24 | TYR 22 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | ILE 187 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | ILE 187 | - | VdWContact |
| ALA 34 | NTc.Cm15 | PHE 188 | - | HBAcceptor |
| ALA 34 | NTc.Cm15 | PHE 188 | - | VdWContact |
| GLY 35 | NTc.Cm14 | PHE 188 | - | VdWContact |
| PRO 36 | NTc.Cm13 | PRO 186 | 45.52x52 | Hydrophobic |
| PRO 36 | NTc.Cm13 | PRO 186 | 45.52x52 | VdWContact |
| PRO 36 | NTc.Cm13 | PHE 188 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | PHE 188 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLN 201 | 5.39x40 | VdWContact |
| PRO 36 | NTc.Cm13 | ILE 267 | 6.62x62 | VdWContact |
| GLN 37 | NTc.Cm12 | PRO 186 | 45.52x52 | VdWContact |
| SER 39 | NTc.Cm10 | ILE 267 | 6.62x62 | HBDonor |
| SER 39 | NTc.Cm10 | ILE 267 | 6.62x62 | VdWContact |
| VAL 44 | NTc.Cm5 | ILE 30 | - | Hydrophobic |
| LEU 47 | NTc.Cm2 | TYR 24 | - | Hydrophobic |
| LEU 47 | NTc.Cm2 | TYR 27 | - | Hydrophobic |
| ASN 49 | CX.1 | TYR 24 | - | Hydrophobic |
| ASN 49 | CX.1 | TYR 24 | - | VdWContact |
| LYS 51 | CX.5 | TYR 24 | - | Hydrophobic |
| LYS 51 | CX.5 | LEU 29 | - | Hydrophobic |
| GLN 52 | cxb1.1 | ILE 30 | - | HBAcceptor |
| GLN 52 | cxb1.1 | ILE 30 | - | Hydrophobic |
| GLN 52 | cxb1.1 | ILE 30 | - | VdWContact |
| VAL 53 | cxb1.2 | TYR 27 | - | Hydrophobic |
| VAL 53 | cxb1.2 | TYR 27 | - | VdWContact |
| VAL 53 | cxb1.2 | LEU 29 | - | Hydrophobic |
| CYS 54 | cxb1.5 | GLU 28 | - | HBDonor |
| CYS 54 | cxb1.5 | GLU 28 | - | VdWContact |
| CYS 54 | cxb1.5 | ILE 30 | - | VdWContact |
| LYS 64 | B1.3 | THR 9 | - | VdWContact |
