Predicted complex interactions
CXCL7_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 19 | NTc.Cm44 | ASN 181 | - | HBAcceptor |
| LEU 19 | NTc.Cm44 | ASN 181 | - | VdWContact |
| ASP 20 | NTc.Cm43 | ARG 183 | - | HBAcceptor |
| ASP 20 | NTc.Cm43 | ARG 183 | - | VdWContact |
| SER 21 | NTc.Cm42 | ASN 181 | - | VdWContact |
| SER 21 | NTc.Cm42 | ARG 183 | - | VdWContact |
| ASP 22 | NTc.Cm41 | ARG 37 | 1.28x28 | Anionic |
| ASP 22 | NTc.Cm41 | ARG 37 | 1.28x28 | HBAcceptor |
| ASP 22 | NTc.Cm41 | ARG 37 | 1.28x28 | VdWContact |
| ASP 22 | NTc.Cm41 | ARG 183 | - | Anionic |
| ASP 22 | NTc.Cm41 | ARG 183 | - | HBAcceptor |
| ASP 22 | NTc.Cm41 | ARG 183 | - | VdWContact |
| LEU 23 | NTc.Cm40 | LYS 41 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm40 | ASN 100 | 2.63x63 | VdWContact |
| LEU 23 | NTc.Cm40 | ALA 101 | 2.64x64 | VdWContact |
| LEU 23 | NTc.Cm40 | VAL 102 | 2.65x65 | VdWContact |
| LEU 23 | NTc.Cm40 | HIS 103 | 2.66x66 | VdWContact |
| LEU 23 | NTc.Cm40 | GLY 104 | 23.49x49 | VdWContact |
| LEU 23 | NTc.Cm40 | ARG 183 | - | VdWContact |
| TYR 24 | NTc.Cm39 | ARG 183 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | ARG 183 | - | PiCation |
| TYR 24 | NTc.Cm39 | ARG 183 | - | VdWContact |
| TYR 24 | NTc.Cm39 | ILE 185 | 45.51x51 | Hydrophobic |
| TYR 24 | NTc.Cm39 | ILE 185 | 45.51x51 | VdWContact |
| ALA 25 | NTc.Cm38 | LEU 44 | 1.35x35 | Hydrophobic |
| ALA 25 | NTc.Cm38 | GLN 286 | 7.36x35 | Hydrophobic |
| GLU 26 | NTc.Cm37 | ILE 185 | 45.51x51 | Hydrophobic |
| GLU 26 | NTc.Cm37 | ILE 185 | 45.51x51 | VdWContact |
| GLU 26 | NTc.Cm37 | PRO 186 | 45.52x52 | VdWContact |
| LEU 27 | NTc.Cm36 | LYS 33 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | LYS 33 | - | VdWContact |
| LEU 27 | NTc.Cm36 | VAL 36 | 1.27x27 | Hydrophobic |
| LEU 27 | NTc.Cm36 | VAL 36 | 1.27x27 | VdWContact |
| LEU 27 | NTc.Cm36 | ARG 37 | 1.28x28 | Hydrophobic |
| LEU 27 | NTc.Cm36 | ARG 37 | 1.28x28 | VdWContact |
| LEU 27 | NTc.Cm36 | ASP 282 | 7.32x31 | Hydrophobic |
| LEU 27 | NTc.Cm36 | ASP 282 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | LYS 33 | - | HBAcceptor |
| ARG 28 | NTc.Cm35 | LYS 33 | - | VdWContact |
| ARG 28 | NTc.Cm35 | ILE 272 | - | VdWContact |
| ARG 28 | NTc.Cm35 | SER 278 | 7.28x27 | VdWContact |
| ARG 28 | NTc.Cm35 | MET 281 | 7.31x30 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 282 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 282 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 282 | 7.32x31 | VdWContact |
| MET 30 | NTc.Cm33 | ILE 30 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | ILE 30 | - | VdWContact |
| MET 30 | NTc.Cm33 | CYS 31 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 31 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 31 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ILE 272 | - | VdWContact |
| ILE 32 | NTc.Cm31 | THR 273 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 275 | 7.25x24 | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 275 | 7.25x24 | VdWContact |
| ILE 32 | NTc.Cm31 | SER 278 | 7.28x27 | VdWContact |
| LYS 33 | NTc.Cm30 | GLU 28 | - | Cationic |
| LYS 33 | NTc.Cm30 | GLU 28 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | GLU 28 | - | VdWContact |
| LYS 33 | NTc.Cm30 | THR 273 | - | VdWContact |
| THR 35 | NTc.Cm28 | TYR 27 | - | Hydrophobic |
| THR 35 | NTc.Cm28 | TYR 27 | - | VdWContact |
| THR 35 | NTc.Cm28 | GLU 28 | - | VdWContact |
| GLY 37 | NTc.Cm26 | TYR 27 | - | VdWContact |
| ILE 38 | NTc.Cm25 | TYR 27 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 13 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 13 | - | VdWContact |
| HIS 39 | NTc.Cm24 | TYR 22 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | TYR 13 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | TYR 13 | - | VdWContact |
| LYS 41 | NTc.Cm22 | GLU 15 | - | Cationic |
| LYS 41 | NTc.Cm22 | GLU 15 | - | HBDonor |
| LYS 41 | NTc.Cm22 | GLU 15 | - | VdWContact |
| ASN 42 | NTc.Cm21 | TYR 22 | - | VdWContact |
| ASN 42 | NTc.Cm21 | TYR 24 | - | Hydrophobic |
| ASN 42 | NTc.Cm21 | TYR 24 | - | VdWContact |
| LYS 51 | NTc.Cm12 | ILE 187 | - | VdWContact |
| LYS 51 | NTc.Cm12 | LYS 197 | 5.35x36 | VdWContact |
| GLY 52 | NTc.Cm11 | PRO 186 | 45.52x52 | VdWContact |
| THR 53 | NTc.Cm10 | PRO 186 | 45.52x52 | Hydrophobic |
| THR 53 | NTc.Cm10 | PRO 186 | 45.52x52 | VdWContact |
| THR 53 | NTc.Cm10 | PHE 188 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | PHE 188 | - | VdWContact |
| HIS 54 | NTc.Cm9 | ARG 263 | 6.58x58 | PiCation |
| HIS 54 | NTc.Cm9 | ARG 263 | 6.58x58 | VdWContact |
| ASN 56 | NTc.Cm7 | LYS 197 | 5.35x36 | HBAcceptor |
| ASN 56 | NTc.Cm7 | LYS 197 | 5.35x36 | Hydrophobic |
| ASN 56 | NTc.Cm7 | LYS 197 | 5.35x36 | VdWContact |
| ASN 56 | NTc.Cm7 | ILE 267 | 6.62x62 | HBDonor |
| ASN 56 | NTc.Cm7 | ILE 267 | 6.62x62 | Hydrophobic |
| ASN 56 | NTc.Cm7 | ILE 267 | 6.62x62 | VdWContact |
| ILE 61 | NTc.Cm2 | ILE 30 | - | Hydrophobic |
| ILE 61 | NTc.Cm2 | ILE 30 | - | VdWContact |
| LEU 64 | CX.4 | TYR 24 | - | Hydrophobic |
| LEU 64 | CX.4 | TYR 24 | - | VdWContact |
| LEU 64 | CX.4 | TYR 27 | - | Hydrophobic |
| ASP 66 | cxb1.1 | TYR 24 | - | Hydrophobic |
| ASP 66 | cxb1.1 | TYR 24 | - | VdWContact |
| ARG 68 | cxb1.5 | TYR 24 | - | VdWContact |
| ARG 68 | cxb1.5 | LEU 29 | - | Hydrophobic |
| LYS 69 | cxb1.6 | LEU 29 | - | VdWContact |
| LYS 69 | cxb1.6 | ILE 30 | - | HBAcceptor |
| LYS 69 | cxb1.6 | ILE 30 | - | Hydrophobic |
| LYS 69 | cxb1.6 | ILE 30 | - | VdWContact |
| ILE 70 | cxb1.8 | TYR 27 | - | Hydrophobic |
| ILE 70 | cxb1.8 | TYR 27 | - | VdWContact |
| ILE 70 | cxb1.8 | GLU 28 | - | VdWContact |
| ILE 70 | cxb1.8 | LEU 29 | - | Hydrophobic |
| CYS 71 | cxb1.10 | GLU 28 | - | HBDonor |
| CYS 71 | cxb1.10 | GLU 28 | - | VdWContact |
| ARG 78 | B1.3 | TYR 13 | - | VdWContact |
| LYS 81 | B1.6 | TYR 11 | - | HBDonor |
| LYS 81 | B1.6 | TYR 11 | - | VdWContact |
