Predicted complex interactions
CXCL9_HUMAN + ACKR4
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 99
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | TRP 97 | 2.60x60 | Hydrophobic |
| THR 1 | NTc.Cm30 | SER 116 | 3.29x29 | VdWContact |
| THR 1 | NTc.Cm30 | TYR 119 | 3.32x32 | CationPi |
| THR 1 | NTc.Cm30 | TYR 119 | 3.32x32 | Hydrophobic |
| THR 1 | NTc.Cm30 | TYR 119 | 3.32x32 | VdWContact |
| THR 1 | NTc.Cm30 | TYR 176 | 4.64x65 | HBDonor |
| THR 1 | NTc.Cm30 | TYR 176 | 4.64x65 | Hydrophobic |
| THR 1 | NTc.Cm30 | TYR 176 | 4.64x65 | VdWContact |
| THR 1 | NTc.Cm30 | GLU 289 | 7.39x38 | Cationic |
| THR 1 | NTc.Cm30 | GLU 289 | 7.39x38 | HBDonor |
| THR 1 | NTc.Cm30 | GLU 289 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm29 | LEU 44 | 1.35x35 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 97 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TYR 119 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm29 | LEU 293 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TRP 97 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TRP 97 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm28 | ASN 100 | 2.63x63 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ASN 100 | 2.63x63 | VdWContact |
| VAL 3 | NTc.Cm28 | CYS 184 | 45.50x50 | VdWContact |
| VAL 4 | NTc.Cm27 | ILE 185 | 45.51x51 | VdWContact |
| ARG 5 | NTc.Cm26 | GLU 204 | 5.42x43 | Cationic |
| ARG 5 | NTc.Cm26 | ARG 263 | 6.58x58 | VdWContact |
| ARG 5 | NTc.Cm26 | ASP 282 | 7.32x31 | VdWContact |
| ARG 5 | NTc.Cm26 | GLU 289 | 7.39x38 | Cationic |
| LYS 6 | NTc.Cm25 | ILE 267 | 6.62x62 | Hydrophobic |
| LYS 6 | NTc.Cm25 | ILE 267 | 6.62x62 | VdWContact |
| GLY 7 | NTc.Cm24 | ARG 263 | 6.58x58 | HBAcceptor |
| GLY 7 | NTc.Cm24 | ARG 263 | 6.58x58 | VdWContact |
| GLY 7 | NTc.Cm24 | SER 278 | 7.28x27 | HBAcceptor |
| GLY 7 | NTc.Cm24 | SER 278 | 7.28x27 | VdWContact |
| GLY 7 | NTc.Cm24 | ASP 282 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 33 | - | HBAcceptor |
| ARG 8 | NTc.Cm23 | LYS 33 | - | Hydrophobic |
| ARG 8 | NTc.Cm23 | LYS 33 | - | VdWContact |
| ARG 8 | NTc.Cm23 | VAL 36 | 1.27x27 | VdWContact |
| ARG 8 | NTc.Cm23 | SER 278 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm23 | SER 278 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 279 | 7.29x28 | HBDonor |
| ARG 8 | NTc.Cm23 | LYS 279 | 7.29x28 | VdWContact |
| ARG 8 | NTc.Cm23 | ARG 280 | 7.30x29 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 282 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 282 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm23 | ASP 282 | 7.32x31 | Hydrophobic |
| ARG 8 | NTc.Cm23 | ASP 282 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm23 | ILE 283 | 7.33x32 | VdWContact |
| CYS 9 | NTc.Cm22 | LYS 33 | - | VdWContact |
| SER 10 | NTc.Cm21 | ILE 30 | - | VdWContact |
| SER 10 | NTc.Cm21 | CYS 31 | - | HBAcceptor |
| SER 10 | NTc.Cm21 | CYS 31 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 31 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | ILE 272 | - | VdWContact |
| ILE 12 | NTc.Cm19 | THR 273 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 275 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm19 | CYS 275 | 7.25x24 | VdWContact |
| SER 13 | NTc.Cm18 | GLU 28 | - | HBDonor |
| SER 13 | NTc.Cm18 | GLU 28 | - | VdWContact |
| ASN 15 | NTc.Cm16 | GLN 26 | - | HBDonor |
| ASN 15 | NTc.Cm16 | GLN 26 | - | VdWContact |
| ASN 15 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| ASN 15 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ASN 15 | NTc.Cm16 | GLU 28 | - | HBAcceptor |
| ASN 15 | NTc.Cm16 | GLU 28 | - | VdWContact |
| GLY 17 | NTc.Cm14 | TYR 27 | - | VdWContact |
| ILE 19 | NTc.Cm12 | TYR 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| SER 23 | NTc.Cm8 | TYR 24 | - | HBDonor |
| SER 23 | NTc.Cm8 | TYR 24 | - | VdWContact |
| ALA 31 | CX.1 | ASN 179 | - | HBAcceptor |
| ALA 31 | CX.1 | ASN 179 | - | VdWContact |
| PRO 32 | CX.4 | ILE 187 | - | Hydrophobic |
| SER 33 | CX.5 | ASN 179 | - | VdWContact |
| SER 33 | CX.5 | ILE 185 | 45.51x51 | VdWContact |
| PRO 34 | cxb1.1 | ARG 183 | - | VdWContact |
| PRO 34 | cxb1.1 | ILE 185 | 45.51x51 | VdWContact |
| SER 35 | cxb1.2 | ILE 185 | 45.51x51 | VdWContact |
| GLU 37 | cxb1.6 | PRO 186 | 45.52x52 | Hydrophobic |
| GLU 37 | cxb1.6 | PRO 186 | 45.52x52 | VdWContact |
| GLU 37 | cxb1.6 | PHE 188 | - | Hydrophobic |
| GLU 37 | cxb1.6 | PHE 188 | - | VdWContact |
| ILE 42 | cxb1.14 | ILE 30 | - | Hydrophobic |
| ILE 42 | cxb1.14 | ILE 30 | - | VdWContact |
| LEU 45 | B1.1 | TYR 24 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 24 | - | VdWContact |
| VAL 49 | B1.5 | TYR 24 | - | Hydrophobic |
| VAL 49 | B1.5 | LEU 29 | - | Hydrophobic |
| GLN 50 | B1.6 | LEU 29 | - | VdWContact |
| GLN 50 | B1.6 | ILE 30 | - | HBAcceptor |
| GLN 50 | B1.6 | ILE 30 | - | Hydrophobic |
| GLN 50 | B1.6 | ILE 30 | - | VdWContact |
| THR 51 | B1.7 | TYR 27 | - | Hydrophobic |
| THR 51 | B1.7 | TYR 27 | - | VdWContact |
| CYS 52 | b1b2.4 | GLU 28 | - | HBDonor |
| CYS 52 | b1b2.4 | GLU 28 | - | VdWContact |
| CYS 52 | b1b2.4 | ILE 30 | - | Hydrophobic |
| CYS 52 | b1b2.4 | ILE 30 | - | VdWContact |
| ASP 56 | b1b2.9 | ARG 190 | - | Anionic |
| ASP 56 | b1b2.9 | ARG 190 | - | VdWContact |
