Predicted complex interactions
XCL1_HUMAN + ACKR4
SUMMARY
- Chemokine
- XCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR4 View partner entry
- Partner description
- UniProt: Q9NPB9; Gene: ackr4_human; Family: Chemokine
- Interactions detected
- 96
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | TYR 176 | 4.64x65 | HBDonor |
| VAL 1 | NTc.Cm30 | TYR 176 | 4.64x65 | VdWContact |
| VAL 1 | NTc.Cm30 | TYR 256 | 6.51x51 | HBAcceptor |
| VAL 1 | NTc.Cm30 | LYS 260 | 6.55x55 | Hydrophobic |
| VAL 1 | NTc.Cm30 | LYS 260 | 6.55x55 | VdWContact |
| VAL 1 | NTc.Cm30 | ILE 285 | 7.35x34 | Hydrophobic |
| VAL 1 | NTc.Cm30 | GLU 289 | 7.39x38 | VdWContact |
| GLY 2 | NTc.Cm29 | TYR 176 | 4.64x65 | HBDonor |
| GLY 2 | NTc.Cm29 | TYR 176 | 4.64x65 | VdWContact |
| GLY 2 | NTc.Cm29 | GLU 289 | 7.39x38 | VdWContact |
| SER 3 | NTc.Cm28 | GLU 289 | 7.39x38 | HBDonor |
| SER 3 | NTc.Cm28 | GLU 289 | 7.39x38 | VdWContact |
| GLU 4 | NTc.Cm27 | ILE 185 | 45.51x51 | Hydrophobic |
| GLU 4 | NTc.Cm27 | PRO 186 | 45.52x52 | VdWContact |
| GLU 4 | NTc.Cm27 | ARG 263 | 6.58x58 | Anionic |
| GLU 4 | NTc.Cm27 | ARG 263 | 6.58x58 | HBAcceptor |
| GLU 4 | NTc.Cm27 | ARG 263 | 6.58x58 | VdWContact |
| VAL 5 | NTc.Cm26 | ARG 37 | 1.28x28 | Hydrophobic |
| VAL 5 | NTc.Cm26 | ALA 40 | 1.31x31 | Hydrophobic |
| VAL 5 | NTc.Cm26 | LEU 44 | 1.35x35 | Hydrophobic |
| VAL 5 | NTc.Cm26 | ARG 183 | - | HBAcceptor |
| VAL 5 | NTc.Cm26 | ARG 183 | - | VdWContact |
| SER 6 | NTc.Cm25 | LYS 33 | - | HBAcceptor |
| SER 6 | NTc.Cm25 | LYS 33 | - | VdWContact |
| SER 6 | NTc.Cm25 | ARG 183 | - | HBAcceptor |
| SER 6 | NTc.Cm25 | ARG 183 | - | VdWContact |
| SER 6 | NTc.Cm25 | ASP 282 | 7.32x31 | VdWContact |
| ASP 7 | NTc.Cm24 | ASN 179 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ASN 181 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | ASN 181 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 183 | - | Anionic |
| ASP 7 | NTc.Cm24 | ARG 183 | - | VdWContact |
| LYS 8 | NTc.Cm23 | ILE 32 | - | VdWContact |
| LYS 8 | NTc.Cm23 | LYS 33 | - | HBAcceptor |
| LYS 8 | NTc.Cm23 | LYS 33 | - | VdWContact |
| LYS 8 | NTc.Cm23 | GLU 34 | - | Cationic |
| LYS 8 | NTc.Cm23 | GLU 34 | - | HBDonor |
| LYS 8 | NTc.Cm23 | GLU 34 | - | VdWContact |
| LYS 8 | NTc.Cm23 | ARG 37 | 1.28x28 | VdWContact |
| LYS 8 | NTc.Cm23 | ARG 183 | - | VdWContact |
| ARG 9 | NTc.Cm22 | ILE 30 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | ILE 30 | - | VdWContact |
| ARG 9 | NTc.Cm22 | CYS 31 | - | VdWContact |
| THR 10 | NTc.Cm21 | CYS 31 | - | HBAcceptor |
| THR 10 | NTc.Cm21 | CYS 31 | - | HBDonor |
| THR 10 | NTc.Cm21 | CYS 31 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 31 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | SER 278 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm18 | GLU 28 | - | HBDonor |
| SER 13 | NTc.Cm18 | GLU 28 | - | VdWContact |
| THR 15 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| THR 15 | NTc.Cm16 | TYR 27 | - | VdWContact |
| THR 15 | NTc.Cm16 | GLU 28 | - | VdWContact |
| GLN 17 | NTc.Cm14 | GLN 26 | - | HBDonor |
| GLN 17 | NTc.Cm14 | GLN 26 | - | VdWContact |
| GLN 17 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| GLN 17 | NTc.Cm14 | TYR 27 | - | VdWContact |
| LEU 19 | NTc.Cm12 | TYR 24 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 27 | - | VdWContact |
| PRO 20 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TYR 22 | - | VdWContact |
| SER 22 | NTc.Cm9 | TYR 13 | - | VdWContact |
| ARG 23 | NTc.Cm8 | GLU 17 | - | Cationic |
| ARG 23 | NTc.Cm8 | GLU 17 | - | HBDonor |
| ARG 23 | NTc.Cm8 | GLU 17 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 22 | - | CationPi |
| ARG 23 | NTc.Cm8 | TYR 22 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 24 | - | HBDonor |
| ARG 23 | NTc.Cm8 | TYR 24 | - | VdWContact |
| ARG 35 | cxb1.5 | ARG 190 | - | VdWContact |
| ILE 38 | cxb1.8 | ILE 30 | - | Hydrophobic |
| ILE 38 | cxb1.8 | ILE 30 | - | VdWContact |
| THR 41 | cxb1.14 | TYR 24 | - | Hydrophobic |
| THR 41 | cxb1.14 | TYR 24 | - | VdWContact |
| LYS 42 | cxb1.15 | MET 18 | - | Hydrophobic |
| ARG 43 | cxb1.16 | GLY 20 | - | HBDonor |
| ARG 43 | cxb1.16 | GLY 20 | - | VdWContact |
| ARG 43 | cxb1.16 | THR 21 | - | VdWContact |
| LEU 45 | B1.2 | TYR 24 | - | Hydrophobic |
| LEU 45 | B1.2 | TYR 24 | - | VdWContact |
| LEU 45 | B1.2 | LEU 29 | - | Hydrophobic |
| LYS 46 | B1.3 | LEU 29 | - | VdWContact |
| LYS 46 | B1.3 | ILE 30 | - | HBAcceptor |
| LYS 46 | B1.3 | ILE 30 | - | Hydrophobic |
| LYS 46 | B1.3 | ILE 30 | - | VdWContact |
| VAL 47 | B1.4 | TYR 27 | - | Hydrophobic |
| VAL 47 | B1.4 | TYR 27 | - | VdWContact |
| VAL 47 | B1.4 | GLU 28 | - | VdWContact |
| VAL 47 | B1.4 | LEU 29 | - | Hydrophobic |
| VAL 47 | B1.4 | LEU 29 | - | VdWContact |
| CYS 48 | B1.5 | GLU 28 | - | HBDonor |
| CYS 48 | B1.5 | GLU 28 | - | Hydrophobic |
| CYS 48 | B1.5 | GLU 28 | - | VdWContact |
| GLN 52 | b1b2.6 | ARG 190 | - | HBAcceptor |
| GLN 52 | b1b2.6 | ARG 190 | - | VdWContact |
