Predicted complex interactions
CXCL12_HUMAN + CCR10
SUMMARY
- Chemokine
- CXCL12_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR10 View partner entry
- Partner description
- UniProt: P46092; Gene: ccr10_human; Family: Chemokine
- Interactions detected
- 132
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm29 | SER 117 | 3.29x29 | HBDonor |
| LYS 1 | NTc.Cm29 | SER 117 | 3.29x29 | VdWContact |
| LYS 1 | NTc.Cm29 | TYR 120 | 3.32x32 | Hydrophobic |
| LYS 1 | NTc.Cm29 | SER 121 | 3.33x33 | HBDonor |
| LYS 1 | NTc.Cm29 | SER 121 | 3.33x33 | VdWContact |
| LYS 1 | NTc.Cm29 | ALA 176 | 4.60x61 | VdWContact |
| PRO 2 | NTc.Cm28 | GLN 44 | 1.35x35 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | SER 296 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | GLN 44 | 1.35x35 | HBAcceptor |
| VAL 3 | NTc.Cm27 | GLN 44 | 1.35x35 | VdWContact |
| VAL 3 | NTc.Cm27 | ALA 98 | 2.60x60 | Hydrophobic |
| SER 4 | NTc.Cm26 | ARG 192 | 45.51x51 | VdWContact |
| LEU 5 | NTc.Cm25 | LEU 292 | 7.35x34 | Hydrophobic |
| LEU 5 | NTc.Cm25 | LEU 292 | 7.35x34 | VdWContact |
| SER 6 | NTc.Cm24 | GLN 37 | - | HBAcceptor |
| SER 6 | NTc.Cm24 | GLN 37 | - | VdWContact |
| TYR 7 | NTc.Cm23 | GLN 37 | - | Hydrophobic |
| TYR 7 | NTc.Cm23 | ARG 185 | - | Hydrophobic |
| TYR 7 | NTc.Cm23 | GLU 186 | - | VdWContact |
| TYR 7 | NTc.Cm23 | ARG 190 | - | PiCation |
| TYR 7 | NTc.Cm23 | ARG 190 | - | VdWContact |
| TYR 7 | NTc.Cm23 | ARG 192 | 45.51x51 | HBAcceptor |
| TYR 7 | NTc.Cm23 | ARG 192 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm22 | ARG 185 | - | HBAcceptor |
| ARG 8 | NTc.Cm22 | ARG 185 | - | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 270 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 270 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 270 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 289 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 289 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 289 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm21 | ARG 185 | - | Anionic |
| CYS 9 | NTc.Cm21 | ARG 185 | - | VdWContact |
| PRO 10 | NTc.Cm20 | LEU 30 | - | Hydrophobic |
| PRO 10 | NTc.Cm20 | LEU 30 | - | VdWContact |
| PRO 10 | NTc.Cm20 | CYS 31 | - | HBAcceptor |
| PRO 10 | NTc.Cm20 | CYS 31 | - | VdWContact |
| PRO 10 | NTc.Cm20 | TYR 32 | - | Hydrophobic |
| ARG 12 | NTc.Cm18 | ASP 270 | 6.58x58 | Cationic |
| ARG 12 | NTc.Cm18 | ASP 270 | 6.58x58 | HBDonor |
| ARG 12 | NTc.Cm18 | ASP 270 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm18 | GLU 279 | - | Cationic |
| ARG 12 | NTc.Cm18 | GLU 279 | - | HBDonor |
| ARG 12 | NTc.Cm18 | GLU 279 | - | VdWContact |
| ARG 12 | NTc.Cm18 | LYS 288 | 7.31x30 | VdWContact |
| PHE 13 | NTc.Cm17 | PRO 28 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | ASP 273 | 6.61x61 | VdWContact |
| PHE 13 | NTc.Cm17 | ALA 277 | 6.65x65 | Hydrophobic |
| PHE 13 | NTc.Cm17 | ALA 277 | 6.65x65 | VdWContact |
| PHE 13 | NTc.Cm17 | ARG 278 | - | VdWContact |
| PHE 13 | NTc.Cm17 | GLU 279 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | GLU 279 | - | VdWContact |
| PHE 14 | NTc.Cm16 | PRO 28 | - | VdWContact |
| GLU 15 | NTc.Cm15 | LEU 27 | - | Hydrophobic |
| GLU 15 | NTc.Cm15 | LEU 27 | - | VdWContact |
| GLU 15 | NTc.Cm15 | PRO 28 | - | Hydrophobic |
| VAL 18 | NTc.Cm12 | TYR 22 | - | Hydrophobic |
| VAL 18 | NTc.Cm12 | TYR 22 | - | VdWContact |
| ALA 19 | NTc.Cm11 | ASP 20 | - | Hydrophobic |
| ALA 19 | NTc.Cm11 | TYR 22 | - | HBAcceptor |
| ALA 19 | NTc.Cm11 | TYR 22 | - | Hydrophobic |
| ALA 19 | NTc.Cm11 | TYR 22 | - | VdWContact |
| ARG 20 | NTc.Cm10 | TYR 14 | - | Hydrophobic |
| ARG 20 | NTc.Cm10 | TYR 14 | - | VdWContact |
| ALA 21 | NTc.Cm9 | GLY 16 | - | VdWContact |
| ALA 21 | NTc.Cm9 | ASP 17 | - | VdWContact |
| ALA 21 | NTc.Cm9 | GLU 18 | - | Hydrophobic |
| ALA 21 | NTc.Cm9 | GLU 18 | - | VdWContact |
| ASN 22 | NTc.Cm8 | GLU 18 | - | HBDonor |
| ASN 22 | NTc.Cm8 | GLU 18 | - | VdWContact |
| ASN 22 | NTc.Cm8 | ASP 20 | - | HBDonor |
| ASN 22 | NTc.Cm8 | ASP 20 | - | VdWContact |
| ASN 22 | NTc.Cm8 | TYR 22 | - | Hydrophobic |
| ASN 22 | NTc.Cm8 | TYR 22 | - | VdWContact |
| VAL 23 | NTc.Cm7 | TYR 14 | - | Hydrophobic |
| VAL 23 | NTc.Cm7 | TYR 14 | - | VdWContact |
| LYS 24 | NTc.Cm6 | TYR 14 | - | HBAcceptor |
| LYS 24 | NTc.Cm6 | TYR 14 | - | VdWContact |
| HIS 25 | NTc.Cm5 | TRP 11 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | TRP 11 | - | VdWContact |
| HIS 25 | NTc.Cm5 | GLY 12 | - | VdWContact |
| HIS 25 | NTc.Cm5 | HIS 13 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | HIS 13 | - | VdWContact |
| LEU 26 | NTc.Cm4 | TRP 11 | - | VdWContact |
| LEU 26 | NTc.Cm4 | GLY 12 | - | HBAcceptor |
| LEU 26 | NTc.Cm4 | GLY 12 | - | HBDonor |
| LEU 26 | NTc.Cm4 | GLY 12 | - | VdWContact |
| LEU 26 | NTc.Cm4 | TYR 14 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | TRP 11 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | TRP 11 | - | VdWContact |
| LYS 27 | NTc.Cm3 | TYR 32 | - | HBDonor |
| LYS 27 | NTc.Cm3 | TYR 32 | - | VdWContact |
| ILE 28 | NTc.Cm2 | VAL 9 | - | Hydrophobic |
| ILE 28 | NTc.Cm2 | VAL 9 | - | VdWContact |
| LEU 29 | NTc.Cm1 | LEU 30 | - | Hydrophobic |
| LEU 29 | NTc.Cm1 | TYR 32 | - | VdWContact |
| ASN 33 | cxb1.1 | GLN 184 | - | HBDonor |
| ASN 33 | cxb1.1 | GLN 184 | - | VdWContact |
| ASN 33 | cxb1.1 | ARG 192 | 45.51x51 | VdWContact |
| ASN 33 | cxb1.1 | ILE 194 | - | Hydrophobic |
| CYS 34 | cxb1.2 | ARG 185 | - | Anionic |
| CYS 34 | cxb1.2 | ARG 185 | - | VdWContact |
| ALA 35 | cxb1.5 | GLU 197 | - | VdWContact |
| VAL 39 | cxb1.11 | TRP 11 | - | Hydrophobic |
| VAL 39 | cxb1.11 | LEU 30 | - | Hydrophobic |
| ARG 41 | cxb1.15 | TRP 11 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TYR 22 | - | Hydrophobic |
| LEU 42 | cxb1.16 | LEU 27 | - | Hydrophobic |
| LEU 42 | cxb1.16 | LEU 27 | - | VdWContact |
| LYS 43 | B1.1 | GLY 16 | - | HBDonor |
| LYS 43 | B1.1 | GLY 16 | - | VdWContact |
| ARG 47 | B1.5 | GLU 29 | - | Cationic |
| GLN 48 | B1.6 | TRP 11 | - | Hydrophobic |
| GLN 48 | B1.6 | GLU 29 | - | VdWContact |
| GLN 48 | B1.6 | LEU 30 | - | HBAcceptor |
| GLN 48 | B1.6 | LEU 30 | - | Hydrophobic |
| GLN 48 | B1.6 | LEU 30 | - | VdWContact |
| VAL 49 | B1.7 | LEU 27 | - | Hydrophobic |
| VAL 49 | B1.7 | PRO 28 | - | Hydrophobic |
| VAL 49 | B1.7 | PRO 28 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 28 | - | HBDonor |
| CYS 50 | b1b2.4 | PRO 28 | - | Hydrophobic |
| CYS 50 | b1b2.4 | PRO 28 | - | VdWContact |
| TRP 57 | b1b2.16 | TYR 14 | - | Hydrophobic |
| TRP 57 | b1b2.16 | TYR 14 | - | VdWContact |
| TYR 61 | B2.4 | GLY 12 | - | VdWContact |
| TYR 61 | B2.4 | TYR 14 | - | Hydrophobic |
| TYR 61 | B2.4 | TYR 14 | - | VdWContact |
| ARG 69 | B3.1 | GLU 7 | - | Cationic |
| ARG 69 | B3.1 | GLU 7 | - | HBDonor |
| ARG 69 | B3.1 | GLU 7 | - | VdWContact |
