Predicted complex interactions
CCL2_HUMAN + CCR1
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR1 View partner entry
- Partner description
- UniProt: P32246; Gene: ccr1_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | ALA 31 | 1.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | ALA 34 | 1.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm33 | ALA 34 | 1.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | LYS 94 | 2.64x64 | VdWContact |
| GLN 1 | NTc.Cm33 | LEU 95 | 2.65x65 | HBDonor |
| GLN 1 | NTc.Cm33 | LEU 95 | 2.65x65 | VdWContact |
| GLN 1 | NTc.Cm33 | LYS 96 | 2.66x66 | VdWContact |
| GLN 1 | NTc.Cm33 | ASP 97 | 2.67x67 | Cationic |
| GLN 1 | NTc.Cm33 | ASP 97 | 2.67x67 | HBDonor |
| GLN 1 | NTc.Cm33 | ASP 97 | 2.67x67 | Hydrophobic |
| GLN 1 | NTc.Cm33 | ASP 97 | 2.67x67 | VdWContact |
| PRO 2 | NTc.Cm32 | ASP 92 | 2.62x62 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 93 | 2.63x63 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 93 | 2.63x63 | VdWContact |
| PRO 2 | NTc.Cm32 | LYS 94 | 2.64x64 | HBAcceptor |
| PRO 2 | NTc.Cm32 | LYS 94 | 2.64x64 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 95 | 2.65x65 | VdWContact |
| PRO 2 | NTc.Cm32 | LYS 96 | 2.66x66 | Hydrophobic |
| PRO 2 | NTc.Cm32 | LYS 96 | 2.66x66 | VdWContact |
| PRO 2 | NTc.Cm32 | ASP 97 | 2.67x67 | VdWContact |
| PRO 2 | NTc.Cm32 | ASP 98 | 23.49x49 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 30 | 1.28x28 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 30 | 1.28x28 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 93 | 2.63x63 | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 93 | 2.63x63 | HBDonor |
| ASP 3 | NTc.Cm31 | TYR 93 | 2.63x63 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 93 | 2.63x63 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 94 | 2.64x64 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 94 | 2.64x64 | VdWContact |
| ASP 3 | NTc.Cm31 | THR 182 | - | Hydrophobic |
| ALA 4 | NTc.Cm30 | TYR 93 | 2.63x63 | VdWContact |
| ALA 4 | NTc.Cm30 | LYS 94 | 2.64x64 | Hydrophobic |
| ALA 4 | NTc.Cm30 | LYS 94 | 2.64x64 | VdWContact |
| ILE 5 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| ILE 5 | NTc.Cm29 | TYR 113 | 3.32x32 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| ASN 6 | NTc.Cm28 | TYR 255 | 6.51x51 | HBDonor |
| ASN 6 | NTc.Cm28 | TYR 255 | 6.51x51 | VdWContact |
| ASN 6 | NTc.Cm28 | VAL 283 | 7.35x34 | Hydrophobic |
| ASN 6 | NTc.Cm28 | VAL 283 | 7.35x34 | VdWContact |
| ASN 6 | NTc.Cm28 | GLU 287 | 7.39x38 | HBDonor |
| ASN 6 | NTc.Cm28 | GLU 287 | 7.39x38 | VdWContact |
| ALA 7 | NTc.Cm27 | LYS 94 | 2.64x64 | VdWContact |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | GLU 29 | 1.27x27 | Hydrophobic |
| PRO 8 | NTc.Cm26 | GLU 29 | 1.27x27 | VdWContact |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| PRO 8 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| PRO 8 | NTc.Cm26 | GLN 284 | 7.36x35 | VdWContact |
| VAL 9 | NTc.Cm25 | LYS 26 | 1.24x24 | HBAcceptor |
| VAL 9 | NTc.Cm25 | LYS 26 | 1.24x24 | VdWContact |
| THR 10 | NTc.Cm24 | PRO 23 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | CYS 24 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | VdWContact |
| CYS 11 | NTc.Cm23 | LYS 26 | 1.24x24 | Anionic |
| TYR 13 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | GLU 272 | 7.24x23 | Hydrophobic |
| TYR 13 | NTc.Cm21 | GLU 272 | 7.24x23 | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 273 | 7.25x24 | Hydrophobic |
| TYR 13 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ASP 20 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | ASP 20 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PHE 16 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 18 | - | Hydrophobic |
| ARG 29 | NTc.Cm5 | GLU 177 | - | Cationic |
| ARG 29 | NTc.Cm5 | GLU 177 | - | HBDonor |
| ARG 29 | NTc.Cm5 | GLU 177 | - | VdWContact |
| ARG 29 | NTc.Cm5 | PHE 178 | - | Hydrophobic |
| ARG 29 | NTc.Cm5 | PHE 178 | - | VdWContact |
| ARG 30 | NTc.Cm4 | GLN 175 | - | HBAcceptor |
| ARG 30 | NTc.Cm4 | GLN 175 | - | VdWContact |
| THR 32 | NTc.Cm2 | HIS 186 | - | HBAcceptor |
| THR 32 | NTc.Cm2 | HIS 186 | - | VdWContact |
| SER 33 | NTc.Cm1 | SER 184 | 45.51x51 | HBDonor |
| SER 33 | NTc.Cm1 | SER 184 | 45.51x51 | VdWContact |
| SER 34 | CX.1 | LEU 185 | 45.52x52 | HBDonor |
| SER 34 | CX.1 | LEU 185 | 45.52x52 | VdWContact |
| SER 34 | CX.1 | PHE 187 | - | HBAcceptor |
| SER 34 | CX.1 | PHE 187 | - | VdWContact |
| SER 34 | CX.1 | LEU 192 | 5.31x32 | VdWContact |
| SER 34 | CX.1 | LYS 196 | 5.35x36 | VdWContact |
| LYS 35 | CX.5 | GLN 265 | 6.61x61 | HBAcceptor |
| LYS 35 | CX.5 | GLN 265 | 6.61x61 | VdWContact |
| PRO 37 | cxb1.2 | GLN 265 | 6.61x61 | VdWContact |
| PRO 37 | cxb1.2 | ASP 266 | 6.62x62 | VdWContact |
| LYS 38 | cxb1.5 | GLU 272 | 7.24x23 | Cationic |
| GLU 39 | cxb1.6 | HIS 189 | - | HBDonor |
| GLU 39 | cxb1.6 | HIS 189 | - | Hydrophobic |
| GLU 39 | cxb1.6 | HIS 189 | - | VdWContact |
| ILE 42 | cxb1.10 | PRO 23 | - | Hydrophobic |
| ILE 42 | cxb1.10 | PRO 23 | - | VdWContact |
| ILE 42 | cxb1.10 | PHE 178 | - | Hydrophobic |
| ILE 42 | cxb1.10 | PHE 178 | - | VdWContact |
| LYS 44 | cxb1.14 | PHE 178 | - | Hydrophobic |
| LYS 49 | B1.3 | GLU 15 | - | Cationic |
| LYS 49 | B1.3 | GLU 15 | - | HBDonor |
| LYS 49 | B1.3 | GLU 15 | - | VdWContact |
| GLU 50 | B1.4 | PRO 23 | - | Hydrophobic |
| GLU 50 | B1.4 | PRO 23 | - | VdWContact |
| GLU 50 | B1.4 | GLN 25 | - | HBAcceptor |
| GLU 50 | B1.4 | GLN 25 | - | VdWContact |
| GLU 50 | B1.4 | PHE 178 | - | Hydrophobic |
| ILE 51 | B1.5 | TYR 18 | - | Hydrophobic |
| ILE 51 | B1.5 | TYR 18 | - | VdWContact |
| ILE 51 | B1.5 | ALA 21 | - | Hydrophobic |
| CYS 52 | B1.6 | ALA 21 | - | HBDonor |
| CYS 52 | B1.6 | ALA 21 | - | VdWContact |
| CYS 52 | B1.6 | PRO 23 | - | VdWContact |
