Predicted complex interactions
CCL22_HUMAN + CCR1
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR1 View partner entry
- Partner description
- UniProt: P32246; Gene: ccr1_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | GLU 287 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 287 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 287 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 291 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 113 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 114 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 114 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 114 | 3.33x33 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 185 | 45.52x52 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLN 199 | 5.38x39 | HBAcceptor |
| TYR 3 | NTc.Cm33 | GLN 199 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLN 199 | 5.38x39 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 255 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | ILE 259 | 6.55x55 | Hydrophobic |
| GLY 4 | NTc.Cm32 | VAL 283 | 7.35x34 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 287 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 287 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | TYR 93 | 2.63x63 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TYR 93 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm31 | LYS 94 | 2.64x64 | VdWContact |
| ASN 6 | NTc.Cm30 | CYS 183 | 45.50x50 | VdWContact |
| ASN 6 | NTc.Cm30 | SER 184 | 45.51x51 | VdWContact |
| ASN 6 | NTc.Cm30 | LEU 185 | 45.52x52 | VdWContact |
| MET 7 | NTc.Cm29 | LYS 26 | 1.24x24 | HBAcceptor |
| MET 7 | NTc.Cm29 | LYS 26 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm28 | LYS 26 | 1.24x24 | Hydrophobic |
| GLU 8 | NTc.Cm28 | LYS 26 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 30 | 1.28x28 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 30 | 1.28x28 | VdWContact |
| GLU 8 | NTc.Cm28 | LYS 94 | 2.64x64 | Anionic |
| GLU 8 | NTc.Cm28 | LYS 94 | 2.64x64 | HBAcceptor |
| GLU 8 | NTc.Cm28 | LYS 94 | 2.64x64 | VdWContact |
| GLU 8 | NTc.Cm28 | ASP 280 | 7.32x31 | Hydrophobic |
| GLU 8 | NTc.Cm28 | GLN 284 | 7.36x35 | HBAcceptor |
| GLU 8 | NTc.Cm28 | GLN 284 | 7.36x35 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 30 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | TYR 93 | 2.63x63 | HBAcceptor |
| ASP 9 | NTc.Cm27 | TYR 93 | 2.63x63 | VdWContact |
| ASP 9 | NTc.Cm27 | LYS 94 | 2.64x64 | Anionic |
| ASP 9 | NTc.Cm27 | THR 182 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | THR 182 | - | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 23 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | CYS 24 | - | Cationic |
| ARG 14 | NTc.Cm22 | GLU 272 | 7.24x23 | Cationic |
| ARG 14 | NTc.Cm22 | GLU 272 | 7.24x23 | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 272 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 273 | 7.25x24 | Cationic |
| ARG 14 | NTc.Cm22 | CYS 273 | 7.25x24 | HBDonor |
| ARG 14 | NTc.Cm22 | CYS 273 | 7.25x24 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 276 | 7.28x27 | VdWContact |
| ASP 15 | NTc.Cm21 | ASP 20 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | TYR 18 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | ALA 21 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 16 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 16 | - | VdWContact |
| TYR 19 | NTc.Cm17 | TYR 18 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 18 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 18 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | TYR 18 | - | VdWContact |
| ARG 24 | NTc.Cm12 | TYR 10 | - | CationPi |
| ARG 24 | NTc.Cm12 | TYR 10 | - | VdWContact |
| HIS 28 | NTc.Cm8 | PHE 178 | - | Hydrophobic |
| TYR 30 | NTc.Cm6 | PHE 178 | - | Hydrophobic |
| TYR 30 | NTc.Cm6 | PHE 178 | - | PiStacking |
| SER 33 | NTc.Cm3 | GLN 175 | - | VdWContact |
| SER 33 | NTc.Cm3 | GLU 177 | - | HBDonor |
| SER 33 | NTc.Cm3 | GLU 177 | - | VdWContact |
| ASP 34 | NTc.Cm2 | LYS 173 | - | Anionic |
| ASP 34 | NTc.Cm2 | GLN 175 | - | HBDonor |
| ASP 34 | NTc.Cm2 | GLN 175 | - | VdWContact |
| ASP 34 | NTc.Cm2 | HIS 186 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | HIS 186 | - | VdWContact |
| ASP 34 | NTc.Cm2 | HIS 189 | - | VdWContact |
| CYS 36 | CX.1 | HIS 189 | - | VdWContact |
| PRO 37 | CX.5 | LEU 192 | 5.31x32 | Hydrophobic |
| PRO 37 | CX.5 | LEU 192 | 5.31x32 | VdWContact |
| VAL 42 | cxb1.7 | PRO 23 | - | Hydrophobic |
| ARG 47 | cxb1.15 | THR 13 | - | VdWContact |
| LYS 49 | B1.1 | GLU 15 | - | Cationic |
| LYS 49 | B1.1 | TYR 18 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 18 | - | VdWContact |
| GLU 50 | B1.2 | THR 22 | - | VdWContact |
| GLU 50 | B1.2 | PRO 23 | - | Hydrophobic |
| GLU 50 | B1.2 | GLN 25 | - | VdWContact |
| ILE 51 | B1.3 | TYR 18 | - | Hydrophobic |
| ILE 51 | B1.3 | TYR 18 | - | VdWContact |
| ILE 51 | B1.3 | ALA 21 | - | Hydrophobic |
| CYS 52 | B1.4 | ALA 21 | - | HBDonor |
| CYS 52 | B1.4 | ALA 21 | - | VdWContact |
