Predicted complex interactions
CCL8_HUMAN + ACKR1
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR1 View partner entry
- Partner description
- UniProt: Q16570; Gene: ackr1_human; Family: Chemokine
- Interactions detected
- 67
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 2 | NTc.Cm32 | ILE 198 | - | Hydrophobic |
| PRO 2 | NTc.Cm32 | ILE 198 | - | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 199 | - | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 199 | - | HBDonor |
| ASP 3 | NTc.Cm31 | TYR 199 | - | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 199 | - | VdWContact |
| SER 4 | NTc.Cm30 | THR 196 | 45.51x51 | VdWContact |
| SER 4 | NTc.Cm30 | LEU 197 | 45.52x52 | VdWContact |
| VAL 5 | NTc.Cm29 | LEU 197 | 45.52x52 | HBDonor |
| VAL 5 | NTc.Cm29 | LEU 197 | 45.52x52 | Hydrophobic |
| VAL 5 | NTc.Cm29 | LEU 197 | 45.52x52 | VdWContact |
| VAL 5 | NTc.Cm29 | TYR 199 | - | Hydrophobic |
| VAL 5 | NTc.Cm29 | ARG 267 | 6.62x62 | HBAcceptor |
| VAL 5 | NTc.Cm29 | ARG 267 | 6.62x62 | VdWContact |
| SER 6 | NTc.Cm28 | CYS 195 | 45.50x50 | HBDonor |
| SER 6 | NTc.Cm28 | THR 196 | 45.51x51 | VdWContact |
| ILE 7 | NTc.Cm27 | SER 191 | - | VdWContact |
| ILE 7 | NTc.Cm27 | LEU 194 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | THR 196 | 45.51x51 | Hydrophobic |
| PRO 8 | NTc.Cm26 | SER 53 | - | VdWContact |
| PRO 8 | NTc.Cm26 | ASN 55 | - | Hydrophobic |
| ILE 9 | NTc.Cm25 | SER 53 | - | HBAcceptor |
| ILE 9 | NTc.Cm25 | SER 53 | - | VdWContact |
| ILE 9 | NTc.Cm25 | GLN 279 | 7.28x27 | HBAcceptor |
| ILE 9 | NTc.Cm25 | GLN 279 | 7.28x27 | VdWContact |
| THR 10 | NTc.Cm24 | PRO 50 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | CYS 51 | - | VdWContact |
| THR 10 | NTc.Cm24 | HIS 52 | - | HBAcceptor |
| THR 10 | NTc.Cm24 | HIS 52 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | HIS 52 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 51 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 51 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 51 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 51 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | LEU 273 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | LEU 273 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 276 | 7.25x24 | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 276 | 7.25x24 | VdWContact |
| PHE 13 | NTc.Cm21 | GLN 279 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLN 279 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ALA 47 | - | HBDonor |
| ASN 14 | NTc.Cm20 | ALA 47 | - | VdWContact |
| ILE 16 | NTc.Cm18 | ALA 48 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | ASN 44 | - | HBDonor |
| ASN 17 | NTc.Cm17 | ASN 44 | - | VdWContact |
| ARG 18 | NTc.Cm16 | PHE 36 | - | CationPi |
| ARG 18 | NTc.Cm16 | PHE 36 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 40 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 40 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 40 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 41 | - | VdWContact |
| ILE 34 | CX.1 | LYS 269 | 6.64x64 | HBAcceptor |
| ILE 34 | CX.1 | LYS 269 | 6.64x64 | VdWContact |
| GLN 35 | CX.5 | TYR 199 | - | VdWContact |
| GLN 35 | CX.5 | ARG 267 | 6.62x62 | VdWContact |
| ILE 42 | cxb1.10 | PRO 50 | - | Hydrophobic |
| LYS 49 | B1.3 | LEU 45 | - | Hydrophobic |
| LYS 49 | B1.3 | GLU 46 | - | Cationic |
| LYS 49 | B1.3 | GLU 46 | - | HBDonor |
| LYS 49 | B1.3 | GLU 46 | - | VdWContact |
| GLU 50 | B1.4 | PRO 50 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 45 | - | Hydrophobic |
| VAL 51 | B1.5 | LEU 45 | - | VdWContact |
| VAL 51 | B1.5 | ALA 48 | - | Hydrophobic |
| CYS 52 | B1.6 | ALA 48 | - | HBDonor |
| CYS 52 | B1.6 | ALA 48 | - | VdWContact |
| CYS 52 | B1.6 | PRO 50 | - | VdWContact |
