Predicted complex interactions
CXCL12_HUMAN + CCR1
SUMMARY
- Chemokine
- CXCL12_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR1 View partner entry
- Partner description
- UniProt: P32246; Gene: ccr1_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| LYS 1 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| LYS 1 | NTc.Cm29 | CYS 106 | 3.25x25 | Cationic |
| LYS 1 | NTc.Cm29 | SER 110 | 3.29x29 | HBDonor |
| LYS 1 | NTc.Cm29 | SER 110 | 3.29x29 | VdWContact |
| LYS 1 | NTc.Cm29 | TYR 113 | 3.32x32 | CationPi |
| LYS 1 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| LYS 1 | NTc.Cm29 | SER 172 | 4.64x65 | VdWContact |
| LYS 1 | NTc.Cm29 | CYS 183 | 45.50x50 | Cationic |
| LYS 1 | NTc.Cm29 | CYS 183 | 45.50x50 | VdWContact |
| LYS 1 | NTc.Cm29 | SER 184 | 45.51x51 | VdWContact |
| LYS 1 | NTc.Cm29 | GLU 287 | 7.39x38 | VdWContact |
| LYS 1 | NTc.Cm29 | TYR 291 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 41 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 287 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 255 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 255 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm27 | ILE 259 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm27 | VAL 283 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLU 287 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm27 | GLU 287 | 7.39x38 | VdWContact |
| LEU 5 | NTc.Cm25 | GLU 29 | 1.27x27 | Hydrophobic |
| LEU 5 | NTc.Cm25 | ARG 30 | 1.28x28 | Hydrophobic |
| LEU 5 | NTc.Cm25 | ASP 280 | 7.32x31 | Hydrophobic |
| LEU 5 | NTc.Cm25 | ASP 280 | 7.32x31 | VdWContact |
| LEU 5 | NTc.Cm25 | GLN 284 | 7.36x35 | VdWContact |
| SER 6 | NTc.Cm24 | LYS 26 | 1.24x24 | HBAcceptor |
| SER 6 | NTc.Cm24 | LYS 26 | 1.24x24 | VdWContact |
| SER 6 | NTc.Cm24 | SER 262 | 6.58x58 | VdWContact |
| SER 6 | NTc.Cm24 | ASP 280 | 7.32x31 | HBDonor |
| SER 6 | NTc.Cm24 | ASP 280 | 7.32x31 | VdWContact |
| TYR 7 | NTc.Cm23 | GLU 177 | - | HBDonor |
| TYR 7 | NTc.Cm23 | GLU 177 | - | VdWContact |
| TYR 7 | NTc.Cm23 | LYS 196 | 5.35x36 | HBAcceptor |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 265 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 266 | 6.62x62 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 266 | 6.62x62 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 266 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm22 | PHE 269 | 6.65x65 | VdWContact |
| ARG 8 | NTc.Cm22 | GLU 272 | 7.24x23 | HBDonor |
| ARG 8 | NTc.Cm22 | GLU 272 | 7.24x23 | VdWContact |
| ARG 8 | NTc.Cm22 | SER 276 | 7.28x27 | VdWContact |
| PRO 10 | NTc.Cm20 | PRO 23 | - | Hydrophobic |
| PRO 10 | NTc.Cm20 | PRO 23 | - | VdWContact |
| PRO 10 | NTc.Cm20 | CYS 24 | - | HBAcceptor |
| PRO 10 | NTc.Cm20 | CYS 24 | - | VdWContact |
| ARG 12 | NTc.Cm18 | ASP 266 | 6.62x62 | Cationic |
| ARG 12 | NTc.Cm18 | GLU 272 | 7.24x23 | Cationic |
| ARG 12 | NTc.Cm18 | GLU 272 | 7.24x23 | HBDonor |
| ARG 12 | NTc.Cm18 | GLU 272 | 7.24x23 | VdWContact |
| PHE 13 | NTc.Cm17 | ASP 20 | - | Hydrophobic |
| PHE 13 | NTc.Cm17 | ASP 20 | - | VdWContact |
| GLU 15 | NTc.Cm15 | TYR 18 | - | Hydrophobic |
| GLU 15 | NTc.Cm15 | TYR 18 | - | VdWContact |
| GLU 15 | NTc.Cm15 | ALA 21 | - | Hydrophobic |
| VAL 18 | NTc.Cm12 | TYR 18 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | PHE 178 | - | CationPi |
| LYS 27 | NTc.Cm3 | PHE 178 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | PHE 178 | - | VdWContact |
| ILE 28 | NTc.Cm2 | PHE 178 | - | VdWContact |
| LEU 29 | NTc.Cm1 | PHE 178 | - | Hydrophobic |
| LEU 29 | NTc.Cm1 | PHE 178 | - | VdWContact |
| ASN 30 | CX.1 | GLN 175 | - | HBAcceptor |
| ASN 30 | CX.1 | GLN 175 | - | VdWContact |
| THR 31 | CX.4 | PHE 178 | - | Hydrophobic |
| PRO 32 | CX.5 | GLU 177 | - | VdWContact |
| PRO 32 | CX.5 | HIS 186 | - | Hydrophobic |
| PRO 32 | CX.5 | HIS 186 | - | VdWContact |
| ASN 33 | cxb1.1 | LEU 185 | 45.52x52 | HBDonor |
| ASN 33 | cxb1.1 | LEU 185 | 45.52x52 | VdWContact |
| ASN 33 | cxb1.1 | PHE 187 | - | HBAcceptor |
| ASN 33 | cxb1.1 | PHE 187 | - | VdWContact |
| ASN 33 | cxb1.1 | LEU 192 | 5.31x32 | Hydrophobic |
| ASN 33 | cxb1.1 | LEU 192 | 5.31x32 | VdWContact |
| CYS 34 | cxb1.2 | HIS 189 | - | VdWContact |
| VAL 39 | cxb1.11 | PRO 23 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TYR 18 | - | Hydrophobic |
| LEU 42 | cxb1.16 | TYR 18 | - | VdWContact |
| ARG 47 | B1.5 | ASP 17 | - | Cationic |
| ARG 47 | B1.5 | ASP 17 | - | HBDonor |
| ARG 47 | B1.5 | ASP 17 | - | VdWContact |
| GLN 48 | B1.6 | THR 22 | - | VdWContact |
| GLN 48 | B1.6 | PRO 23 | - | Hydrophobic |
| GLN 48 | B1.6 | PRO 23 | - | VdWContact |
| VAL 49 | B1.7 | TYR 18 | - | Hydrophobic |
| VAL 49 | B1.7 | TYR 18 | - | VdWContact |
| VAL 49 | B1.7 | ALA 21 | - | Hydrophobic |
| VAL 49 | B1.7 | ALA 21 | - | VdWContact |
| CYS 50 | b1b2.4 | ALA 21 | - | HBDonor |
| CYS 50 | b1b2.4 | ALA 21 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 23 | - | VdWContact |
