Predicted complex interactions
CXCL4_HUMAN + CCR1
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR1 View partner entry
- Partner description
- UniProt: P32246; Gene: ccr1_human; Family: Chemokine
- Interactions detected
- 116
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 1 | NTc.Cm40 | TRP 90 | 2.60x60 | Hydrophobic |
| GLU 1 | NTc.Cm40 | TRP 90 | 2.60x60 | VdWContact |
| GLU 1 | NTc.Cm40 | CYS 106 | 3.25x25 | VdWContact |
| GLU 1 | NTc.Cm40 | SER 110 | 3.29x29 | HBDonor |
| GLU 1 | NTc.Cm40 | SER 110 | 3.29x29 | VdWContact |
| GLU 1 | NTc.Cm40 | TYR 113 | 3.32x32 | VdWContact |
| GLU 1 | NTc.Cm40 | TYR 114 | 3.33x33 | HBDonor |
| GLU 1 | NTc.Cm40 | TYR 114 | 3.33x33 | VdWContact |
| GLU 1 | NTc.Cm40 | GLY 168 | 4.60x61 | HBDonor |
| GLU 1 | NTc.Cm40 | SER 172 | 4.64x65 | HBDonor |
| GLU 1 | NTc.Cm40 | SER 172 | 4.64x65 | VdWContact |
| GLU 1 | NTc.Cm40 | LYS 173 | - | HBAcceptor |
| GLU 1 | NTc.Cm40 | LYS 173 | - | VdWContact |
| GLU 1 | NTc.Cm40 | CYS 183 | 45.50x50 | VdWContact |
| GLU 1 | NTc.Cm40 | SER 184 | 45.51x51 | VdWContact |
| GLU 1 | NTc.Cm40 | LEU 185 | 45.52x52 | VdWContact |
| ALA 2 | NTc.Cm39 | TRP 90 | 2.60x60 | Hydrophobic |
| ALA 2 | NTc.Cm39 | TRP 90 | 2.60x60 | VdWContact |
| ALA 2 | NTc.Cm39 | TYR 113 | 3.32x32 | Hydrophobic |
| ALA 2 | NTc.Cm39 | TYR 113 | 3.32x32 | VdWContact |
| GLU 3 | NTc.Cm38 | TYR 113 | 3.32x32 | Hydrophobic |
| GLU 3 | NTc.Cm38 | TYR 113 | 3.32x32 | VdWContact |
| GLU 3 | NTc.Cm38 | TYR 114 | 3.33x33 | HBAcceptor |
| GLU 3 | NTc.Cm38 | TYR 114 | 3.33x33 | Hydrophobic |
| GLU 3 | NTc.Cm38 | TYR 114 | 3.33x33 | VdWContact |
| GLU 3 | NTc.Cm38 | LEU 185 | 45.52x52 | Hydrophobic |
| GLU 3 | NTc.Cm38 | LEU 185 | 45.52x52 | VdWContact |
| GLU 3 | NTc.Cm38 | TYR 255 | 6.51x51 | HBAcceptor |
| GLU 3 | NTc.Cm38 | TYR 255 | 6.51x51 | VdWContact |
| GLU 4 | NTc.Cm37 | TYR 41 | 1.39x39 | VdWContact |
| GLU 4 | NTc.Cm37 | LYS 94 | 2.64x64 | Anionic |
| GLU 4 | NTc.Cm37 | LYS 94 | 2.64x64 | VdWContact |
| GLU 4 | NTc.Cm37 | GLU 287 | 7.39x38 | VdWContact |
| GLU 4 | NTc.Cm37 | TYR 291 | 7.43x42 | Hydrophobic |
| GLU 4 | NTc.Cm37 | TYR 291 | 7.43x42 | VdWContact |
| ASP 7 | NTc.Cm34 | TYR 93 | 2.63x63 | HBAcceptor |
| ASP 7 | NTc.Cm34 | TYR 93 | 2.63x63 | VdWContact |
| ASP 7 | NTc.Cm34 | LYS 94 | 2.64x64 | Anionic |
| ASP 7 | NTc.Cm34 | THR 182 | - | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 26 | 1.24x24 | Hydrophobic |
| LEU 8 | NTc.Cm33 | LYS 26 | 1.24x24 | VdWContact |
| LEU 8 | NTc.Cm33 | GLU 29 | 1.27x27 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ARG 30 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ARG 30 | 1.28x28 | VdWContact |
| LEU 8 | NTc.Cm33 | ASP 280 | 7.32x31 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ASP 280 | 7.32x31 | VdWContact |
| GLN 9 | NTc.Cm32 | LYS 26 | 1.24x24 | HBAcceptor |
| GLN 9 | NTc.Cm32 | LYS 26 | 1.24x24 | VdWContact |
| GLN 9 | NTc.Cm32 | GLN 265 | 6.61x61 | VdWContact |
| GLN 9 | NTc.Cm32 | SER 276 | 7.28x27 | HBAcceptor |
| GLN 9 | NTc.Cm32 | SER 276 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | LEU 279 | 7.31x30 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 280 | 7.32x31 | HBDonor |
| GLN 9 | NTc.Cm32 | ASP 280 | 7.32x31 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 23 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | PRO 23 | - | VdWContact |
| LEU 11 | NTc.Cm30 | CYS 24 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 24 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 24 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | GLU 272 | 7.24x23 | Hydrophobic |
| VAL 13 | NTc.Cm28 | GLU 272 | 7.24x23 | VdWContact |
| LYS 14 | NTc.Cm27 | ASP 20 | - | Cationic |
| LYS 14 | NTc.Cm27 | ASP 20 | - | HBDonor |
| LYS 14 | NTc.Cm27 | ASP 20 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | ASP 20 | - | VdWContact |
| LYS 14 | NTc.Cm27 | GLU 272 | 7.24x23 | Cationic |
| LYS 14 | NTc.Cm27 | GLU 272 | 7.24x23 | VdWContact |
| THR 16 | NTc.Cm25 | TYR 18 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | TYR 18 | - | VdWContact |
| THR 16 | NTc.Cm25 | ALA 21 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | PHE 16 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | PHE 16 | - | VdWContact |
| GLN 18 | NTc.Cm23 | TYR 18 | - | VdWContact |
| VAL 19 | NTc.Cm22 | TYR 18 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | ASP 11 | - | Cationic |
| ARG 20 | NTc.Cm21 | ASP 11 | - | HBDonor |
| ARG 20 | NTc.Cm21 | ASP 11 | - | VdWContact |
| ARG 20 | NTc.Cm21 | PHE 16 | - | Hydrophobic |
| ARG 22 | NTc.Cm19 | ASP 11 | - | Cationic |
| ARG 22 | NTc.Cm19 | ASP 11 | - | HBDonor |
| ARG 22 | NTc.Cm19 | ASP 11 | - | VdWContact |
| HIS 23 | NTc.Cm18 | THR 13 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | PHE 178 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | PHE 178 | - | VdWContact |
| ILE 30 | NTc.Cm11 | GLU 177 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | GLN 175 | - | HBAcceptor |
| LYS 31 | NTc.Cm10 | GLN 175 | - | VdWContact |
| ALA 32 | NTc.Cm9 | HIS 186 | - | VdWContact |
| ALA 32 | NTc.Cm9 | HIS 189 | - | Hydrophobic |
| GLY 33 | NTc.Cm8 | HIS 186 | - | VdWContact |
| PRO 34 | NTc.Cm7 | SER 184 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | LEU 185 | 45.52x52 | Hydrophobic |
| PRO 34 | NTc.Cm7 | LEU 185 | 45.52x52 | VdWContact |
| PRO 34 | NTc.Cm7 | LYS 196 | 5.35x36 | HBAcceptor |
| PRO 34 | NTc.Cm7 | LYS 196 | 5.35x36 | VdWContact |
| PRO 37 | NTc.Cm4 | HIS 189 | - | VdWContact |
| PRO 37 | NTc.Cm4 | LEU 192 | 5.31x32 | Hydrophobic |
| PRO 37 | NTc.Cm4 | LEU 192 | 5.31x32 | VdWContact |
| ILE 42 | CX.4 | PRO 23 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 18 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 18 | - | VdWContact |
| ARG 49 | cxb1.10 | ASP 17 | - | Cationic |
| ARG 49 | cxb1.10 | TYR 18 | - | VdWContact |
| ARG 49 | cxb1.10 | GLY 19 | - | VdWContact |
| ARG 49 | cxb1.10 | THR 22 | - | Hydrophobic |
| ARG 49 | cxb1.10 | THR 22 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 23 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 23 | - | VdWContact |
| LYS 50 | cxb1.11 | PHE 178 | - | VdWContact |
| ILE 51 | cxb1.14 | TYR 18 | - | Hydrophobic |
| ILE 51 | cxb1.14 | TYR 18 | - | VdWContact |
| ILE 51 | cxb1.14 | ALA 21 | - | VdWContact |
| ILE 51 | cxb1.14 | PRO 23 | - | VdWContact |
| CYS 52 | cxb1.15 | ALA 21 | - | HBDonor |
| CYS 52 | cxb1.15 | ALA 21 | - | VdWContact |
| CYS 52 | cxb1.15 | PRO 23 | - | VdWContact |
