Predicted complex interactions
CCL1_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm32 | ASN 266 | 6.58x58 | HBDonor |
| LYS 1 | NTc.Cm32 | ASN 266 | 6.58x58 | Hydrophobic |
| LYS 1 | NTc.Cm32 | ASN 266 | 6.58x58 | VdWContact |
| LYS 1 | NTc.Cm32 | GLN 269 | 6.61x61 | VdWContact |
| LYS 1 | NTc.Cm32 | ASP 284 | 7.32x31 | Cationic |
| SER 2 | NTc.Cm31 | TYR 259 | 6.51x51 | HBAcceptor |
| SER 2 | NTc.Cm31 | TYR 259 | 6.51x51 | VdWContact |
| SER 2 | NTc.Cm31 | THR 287 | 7.35x34 | VdWContact |
| SER 2 | NTc.Cm31 | GLU 291 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm31 | GLU 291 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm30 | TRP 98 | 2.60x60 | Hydrophobic |
| MET 3 | NTc.Cm30 | TRP 98 | 2.60x60 | VdWContact |
| MET 3 | NTc.Cm30 | TYR 120 | 3.32x32 | Hydrophobic |
| MET 3 | NTc.Cm30 | TYR 120 | 3.32x32 | VdWContact |
| GLN 4 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| GLN 4 | NTc.Cm29 | TRP 98 | 2.60x60 | VdWContact |
| GLN 4 | NTc.Cm29 | SER 101 | 2.63x63 | HBDonor |
| GLN 4 | NTc.Cm29 | SER 101 | 2.63x63 | VdWContact |
| GLN 4 | NTc.Cm29 | TRP 106 | 23.50x50 | VdWContact |
| GLN 4 | NTc.Cm29 | CYS 190 | 45.50x50 | HBAcceptor |
| GLN 4 | NTc.Cm29 | CYS 190 | 45.50x50 | VdWContact |
| VAL 5 | NTc.Cm28 | ASP 284 | 7.32x31 | Hydrophobic |
| VAL 5 | NTc.Cm28 | GLN 288 | 7.36x35 | Hydrophobic |
| PHE 7 | NTc.Cm26 | LYS 34 | - | Hydrophobic |
| PHE 7 | NTc.Cm26 | VAL 37 | 1.27x27 | Hydrophobic |
| PHE 7 | NTc.Cm26 | VAL 37 | 1.27x27 | VdWContact |
| PHE 7 | NTc.Cm26 | LYS 38 | 1.28x28 | Hydrophobic |
| PHE 7 | NTc.Cm26 | LYS 38 | 1.28x28 | VdWContact |
| ARG 9 | NTc.Cm24 | PRO 31 | - | Hydrophobic |
| ARG 9 | NTc.Cm24 | PRO 31 | - | VdWContact |
| ARG 9 | NTc.Cm24 | CYS 32 | - | VdWContact |
| ARG 9 | NTc.Cm24 | HIS 33 | - | Hydrophobic |
| ARG 9 | NTc.Cm24 | HIS 33 | - | VdWContact |
| ARG 9 | NTc.Cm24 | ASP 185 | - | Cationic |
| ARG 9 | NTc.Cm24 | ASP 185 | - | HBDonor |
| ARG 9 | NTc.Cm24 | ASP 185 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 32 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 32 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 32 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 32 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 277 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | THR 280 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm20 | GLY 29 | - | VdWContact |
| ALA 15 | NTc.Cm18 | TYR 28 | - | Hydrophobic |
| GLN 17 | NTc.Cm16 | TYR 26 | - | Hydrophobic |
| GLN 17 | NTc.Cm16 | TYR 26 | - | VdWContact |
| ILE 19 | NTc.Cm14 | TYR 28 | - | Hydrophobic |
| ILE 19 | NTc.Cm14 | TYR 28 | - | VdWContact |
| ARG 28 | NTc.Cm5 | ASP 185 | - | Cationic |
| SER 31 | NTc.Cm2 | GLU 184 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLU 184 | - | VdWContact |
| ILE 33 | CX.1 | TYR 193 | - | Hydrophobic |
| ILE 40 | cxb1.8 | PRO 31 | - | Hydrophobic |
| LEU 43 | cxb1.14 | TYR 28 | - | Hydrophobic |
| ARG 45 | cxb1.16 | PHE 23 | - | CationPi |
| ARG 45 | cxb1.16 | PHE 23 | - | Hydrophobic |
| ARG 45 | cxb1.16 | PHE 23 | - | VdWContact |
| LYS 47 | B1.2 | ASP 25 | - | Cationic |
| LYS 47 | B1.2 | ASP 25 | - | HBDonor |
| LYS 47 | B1.2 | ASP 25 | - | VdWContact |
| GLU 48 | B1.3 | ALA 30 | - | VdWContact |
| GLU 48 | B1.3 | PRO 31 | - | Hydrophobic |
| ALA 49 | B1.4 | TYR 28 | - | Hydrophobic |
| ALA 49 | B1.4 | TYR 28 | - | VdWContact |
| CYS 50 | B1.5 | TYR 28 | - | HBDonor |
| CYS 50 | B1.5 | TYR 28 | - | VdWContact |
| CYS 50 | B1.5 | GLY 29 | - | HBDonor |
| CYS 50 | B1.5 | GLY 29 | - | VdWContact |
| CYS 50 | B1.5 | PRO 31 | - | VdWContact |
| SER 70 | b2b3.12 | LYS 183 | - | HBAcceptor |
| SER 70 | b2b3.12 | LYS 183 | - | VdWContact |
| LYS 71 | B3.1 | LYS 183 | - | HBAcceptor |
| LYS 71 | B3.1 | LYS 183 | - | VdWContact |
| LYS 71 | B3.1 | SER 186 | - | VdWContact |
