Predicted complex interactions
CCL13_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 127
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 2 | NTc.Cm32 | LYS 180 | - | HBAcceptor |
| ASN 2 | NTc.Cm32 | LYS 180 | - | VdWContact |
| PRO 3 | NTc.Cm31 | ILE 177 | 4.62x63 | Hydrophobic |
| PRO 3 | NTc.Cm31 | ILE 177 | 4.62x63 | VdWContact |
| PRO 3 | NTc.Cm31 | PHE 178 | 4.63x64 | HBAcceptor |
| PRO 3 | NTc.Cm31 | PHE 178 | 4.63x64 | VdWContact |
| PRO 3 | NTc.Cm31 | LYS 180 | - | HBAcceptor |
| PRO 3 | NTc.Cm31 | LYS 180 | - | VdWContact |
| GLN 4 | NTc.Cm30 | ASN 110 | 3.22x22 | HBAcceptor |
| GLN 4 | NTc.Cm30 | ASN 110 | 3.22x22 | VdWContact |
| GLN 4 | NTc.Cm30 | LYS 114 | 3.26x26 | Hydrophobic |
| GLN 4 | NTc.Cm30 | LYS 114 | 3.26x26 | VdWContact |
| GLN 4 | NTc.Cm30 | ILE 176 | 4.61x62 | HBDonor |
| GLN 4 | NTc.Cm30 | ILE 176 | 4.61x62 | VdWContact |
| GLN 4 | NTc.Cm30 | THR 179 | 4.64x65 | VdWContact |
| GLN 4 | NTc.Cm30 | LYS 180 | - | Hydrophobic |
| GLN 4 | NTc.Cm30 | LYS 180 | - | VdWContact |
| GLY 5 | NTc.Cm29 | GLY 175 | 4.60x61 | VdWContact |
| GLY 5 | NTc.Cm29 | ILE 176 | 4.61x62 | HBDonor |
| GLY 5 | NTc.Cm29 | ILE 176 | 4.61x62 | VdWContact |
| GLY 5 | NTc.Cm29 | ILE 177 | 4.62x63 | HBDonor |
| GLY 5 | NTc.Cm29 | ILE 177 | 4.62x63 | VdWContact |
| GLY 5 | NTc.Cm29 | PHE 178 | 4.63x64 | VdWContact |
| GLY 5 | NTc.Cm29 | THR 179 | 4.64x65 | VdWContact |
| LEU 6 | NTc.Cm28 | LYS 114 | 3.26x26 | Hydrophobic |
| LEU 6 | NTc.Cm28 | LYS 114 | 3.26x26 | VdWContact |
| LEU 6 | NTc.Cm28 | THR 117 | 3.29x29 | HBAcceptor |
| LEU 6 | NTc.Cm28 | THR 117 | 3.29x29 | Hydrophobic |
| LEU 6 | NTc.Cm28 | THR 117 | 3.29x29 | VdWContact |
| LEU 6 | NTc.Cm28 | GLY 118 | 3.30x30 | VdWContact |
| LEU 6 | NTc.Cm28 | GLY 175 | 4.60x61 | VdWContact |
| LEU 6 | NTc.Cm28 | ILE 176 | 4.61x62 | Hydrophobic |
| LEU 6 | NTc.Cm28 | ILE 176 | 4.61x62 | VdWContact |
| LEU 6 | NTc.Cm28 | THR 179 | 4.64x65 | HBAcceptor |
| LEU 6 | NTc.Cm28 | THR 179 | 4.64x65 | Hydrophobic |
| LEU 6 | NTc.Cm28 | THR 179 | 4.64x65 | VdWContact |
| ALA 7 | NTc.Cm27 | THR 117 | 3.29x29 | VdWContact |
| ALA 7 | NTc.Cm27 | HIS 121 | 3.33x33 | HBAcceptor |
| ALA 7 | NTc.Cm27 | HIS 121 | 3.33x33 | Hydrophobic |
| ALA 7 | NTc.Cm27 | HIS 121 | 3.33x33 | VdWContact |
| ALA 7 | NTc.Cm27 | THR 179 | 4.64x65 | HBAcceptor |
| ALA 7 | NTc.Cm27 | THR 179 | 4.64x65 | VdWContact |
| ALA 7 | NTc.Cm27 | PRO 192 | 45.52x52 | Hydrophobic |
| ALA 7 | NTc.Cm27 | PHE 194 | - | Hydrophobic |
| ALA 7 | NTc.Cm27 | HIS 202 | 5.38x39 | Hydrophobic |
| GLN 8 | NTc.Cm26 | TRP 98 | 2.60x60 | Hydrophobic |
| GLN 8 | NTc.Cm26 | THR 117 | 3.29x29 | VdWContact |
| GLN 8 | NTc.Cm26 | CYS 190 | 45.50x50 | VdWContact |
| GLN 8 | NTc.Cm26 | PRO 192 | 45.52x52 | VdWContact |
| PRO 9 | NTc.Cm25 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 9 | NTc.Cm25 | TRP 98 | 2.60x60 | VdWContact |
| PRO 9 | NTc.Cm25 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 9 | NTc.Cm25 | TYR 120 | 3.32x32 | VdWContact |
| PRO 9 | NTc.Cm25 | GLU 291 | 7.39x38 | VdWContact |
| PRO 9 | NTc.Cm25 | MET 295 | 7.43x42 | Hydrophobic |
| ASP 10 | NTc.Cm24 | ARG 206 | 5.42x43 | Anionic |
| ASP 10 | NTc.Cm24 | ARG 206 | 5.42x43 | HBAcceptor |
| ASP 10 | NTc.Cm24 | ARG 206 | 5.42x43 | VdWContact |
| ASP 10 | NTc.Cm24 | ILE 263 | 6.55x55 | Hydrophobic |
| ASP 10 | NTc.Cm24 | ILE 263 | 6.55x55 | VdWContact |
| ASP 10 | NTc.Cm24 | THR 287 | 7.35x34 | Hydrophobic |
| ASP 10 | NTc.Cm24 | THR 287 | 7.35x34 | VdWContact |
| ASP 10 | NTc.Cm24 | GLU 291 | 7.39x38 | HBDonor |
| ASP 10 | NTc.Cm24 | GLU 291 | 7.39x38 | VdWContact |
| ALA 11 | NTc.Cm23 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 11 | NTc.Cm23 | GLN 288 | 7.36x35 | HBAcceptor |
| ALA 11 | NTc.Cm23 | GLN 288 | 7.36x35 | Hydrophobic |
| ALA 11 | NTc.Cm23 | GLN 288 | 7.36x35 | VdWContact |
| ALA 11 | NTc.Cm23 | GLU 291 | 7.39x38 | HBDonor |
| ALA 11 | NTc.Cm23 | GLU 291 | 7.39x38 | VdWContact |
| LEU 12 | NTc.Cm22 | LEU 45 | 1.35x35 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TRP 98 | 2.60x60 | Hydrophobic |
| LEU 12 | NTc.Cm22 | ALA 102 | 2.64x64 | Hydrophobic |
| ASN 13 | NTc.Cm21 | PRO 192 | 45.52x52 | Hydrophobic |
| ASN 13 | NTc.Cm21 | PRO 192 | 45.52x52 | VdWContact |
| VAL 14 | NTc.Cm20 | LYS 34 | - | Hydrophobic |
| VAL 14 | NTc.Cm20 | VAL 37 | 1.27x27 | Hydrophobic |
| VAL 14 | NTc.Cm20 | LYS 38 | 1.28x28 | HBAcceptor |
| VAL 14 | NTc.Cm20 | LYS 38 | 1.28x28 | Hydrophobic |
| VAL 14 | NTc.Cm20 | LYS 38 | 1.28x28 | VdWContact |
| VAL 14 | NTc.Cm20 | ASP 284 | 7.32x31 | Hydrophobic |
| SER 16 | NTc.Cm18 | HIS 33 | - | VdWContact |
| SER 16 | NTc.Cm18 | LYS 34 | - | HBAcceptor |
| SER 16 | NTc.Cm18 | LYS 34 | - | VdWContact |
| SER 16 | NTc.Cm18 | LYS 38 | 1.28x28 | HBAcceptor |
| SER 16 | NTc.Cm18 | LYS 38 | 1.28x28 | VdWContact |
| SER 16 | NTc.Cm18 | ASP 185 | - | HBDonor |
| SER 16 | NTc.Cm18 | ASP 185 | - | VdWContact |
| THR 17 | NTc.Cm17 | PRO 31 | - | Hydrophobic |
| THR 17 | NTc.Cm17 | CYS 32 | - | VdWContact |
| THR 17 | NTc.Cm17 | HIS 33 | - | HBAcceptor |
| THR 17 | NTc.Cm17 | HIS 33 | - | Hydrophobic |
| THR 17 | NTc.Cm17 | HIS 33 | - | VdWContact |
| CYS 18 | NTc.Cm16 | CYS 32 | - | HBAcceptor |
| CYS 18 | NTc.Cm16 | CYS 32 | - | HBDonor |
| CYS 18 | NTc.Cm16 | CYS 32 | - | VdWContact |
| PHE 20 | NTc.Cm14 | CYS 32 | - | Hydrophobic |
| PHE 20 | NTc.Cm14 | CYS 32 | - | VdWContact |
| PHE 20 | NTc.Cm14 | CYS 277 | - | Hydrophobic |
| PHE 20 | NTc.Cm14 | THR 280 | 7.28x27 | Hydrophobic |
| THR 21 | NTc.Cm13 | GLY 29 | - | VdWContact |
| SER 23 | NTc.Cm11 | ASP 27 | - | VdWContact |
| SER 23 | NTc.Cm11 | TYR 28 | - | VdWContact |
| SER 24 | NTc.Cm10 | ASP 27 | - | HBDonor |
| SER 24 | NTc.Cm10 | ASP 27 | - | VdWContact |
| LYS 25 | NTc.Cm9 | TYR 26 | - | HBDonor |
| LYS 25 | NTc.Cm9 | TYR 26 | - | Hydrophobic |
| LYS 25 | NTc.Cm9 | TYR 26 | - | VdWContact |
| THR 39 | cxb1.6 | GLU 184 | - | HBDonor |
| THR 39 | cxb1.6 | GLU 184 | - | VdWContact |
| THR 39 | cxb1.6 | TYR 193 | - | VdWContact |
| SER 40 | cxb1.7 | TYR 193 | - | VdWContact |
| ARG 41 | cxb1.8 | GLU 184 | - | Cationic |
| ARG 41 | cxb1.8 | GLU 184 | - | HBDonor |
| ARG 41 | cxb1.8 | GLU 184 | - | VdWContact |
| ARG 41 | cxb1.8 | PRO 192 | 45.52x52 | VdWContact |
| ARG 41 | cxb1.8 | TYR 193 | - | Hydrophobic |
| ARG 41 | cxb1.8 | TYR 193 | - | VdWContact |
| GLN 44 | cxb1.14 | GLU 270 | 6.62x62 | HBDonor |
| GLN 44 | cxb1.14 | GLU 270 | 6.62x62 | VdWContact |
| ILE 48 | B1.2 | PRO 31 | - | Hydrophobic |
| LYS 55 | b1b2.6 | PHE 23 | - | VdWContact |
| GLU 56 | b1b2.9 | PRO 31 | - | Hydrophobic |
| ILE 57 | b1b2.10 | TYR 28 | - | Hydrophobic |
| ILE 57 | b1b2.10 | TYR 28 | - | VdWContact |
| CYS 58 | b1b2.12 | GLY 29 | - | HBDonor |
| CYS 58 | b1b2.12 | GLY 29 | - | VdWContact |
