Predicted complex interactions
CCL14_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 3 | NTc.Cm32 | VAL 187 | - | Hydrophobic |
| SER 6 | NTc.Cm29 | VAL 187 | - | VdWContact |
| SER 7 | NTc.Cm28 | LYS 38 | 1.28x28 | VdWContact |
| SER 7 | NTc.Cm28 | ALA 42 | 1.32x32 | VdWContact |
| SER 7 | NTc.Cm28 | SER 101 | 2.63x63 | VdWContact |
| SER 7 | NTc.Cm28 | ALA 102 | 2.64x64 | VdWContact |
| ARG 8 | NTc.Cm27 | SER 101 | 2.63x63 | VdWContact |
| ARG 8 | NTc.Cm27 | GLU 184 | - | Cationic |
| ARG 8 | NTc.Cm27 | GLU 184 | - | HBDonor |
| ARG 8 | NTc.Cm27 | GLU 184 | - | VdWContact |
| ARG 8 | NTc.Cm27 | ASP 185 | - | Cationic |
| ARG 8 | NTc.Cm27 | ASP 185 | - | VdWContact |
| ARG 8 | NTc.Cm27 | VAL 189 | - | VdWContact |
| PRO 10 | NTc.Cm25 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 10 | NTc.Cm25 | TRP 98 | 2.60x60 | VdWContact |
| PRO 10 | NTc.Cm25 | GLU 291 | 7.39x38 | VdWContact |
| PRO 10 | NTc.Cm25 | MET 295 | 7.43x42 | Hydrophobic |
| PRO 10 | NTc.Cm25 | MET 295 | 7.43x42 | VdWContact |
| TYR 11 | NTc.Cm24 | ASP 284 | 7.32x31 | Hydrophobic |
| TYR 11 | NTc.Cm24 | ASP 284 | 7.32x31 | VdWContact |
| TYR 11 | NTc.Cm24 | THR 287 | 7.35x34 | Hydrophobic |
| TYR 11 | NTc.Cm24 | THR 287 | 7.35x34 | VdWContact |
| TYR 11 | NTc.Cm24 | GLU 291 | 7.39x38 | HBDonor |
| TYR 11 | NTc.Cm24 | GLU 291 | 7.39x38 | VdWContact |
| HIS 12 | NTc.Cm23 | GLU 184 | - | VdWContact |
| HIS 12 | NTc.Cm23 | VAL 189 | - | Hydrophobic |
| HIS 12 | NTc.Cm23 | GLY 191 | 45.51x51 | VdWContact |
| PRO 13 | NTc.Cm22 | LYS 34 | - | Hydrophobic |
| PRO 13 | NTc.Cm22 | VAL 37 | 1.27x27 | Hydrophobic |
| PRO 13 | NTc.Cm22 | LYS 38 | 1.28x28 | Hydrophobic |
| PRO 13 | NTc.Cm22 | ASP 284 | 7.32x31 | Hydrophobic |
| PRO 13 | NTc.Cm22 | ASP 284 | 7.32x31 | VdWContact |
| SER 14 | NTc.Cm21 | LYS 34 | - | VdWContact |
| GLU 15 | NTc.Cm20 | HIS 33 | - | HBAcceptor |
| GLU 15 | NTc.Cm20 | HIS 33 | - | VdWContact |
| GLU 15 | NTc.Cm20 | LYS 34 | - | HBAcceptor |
| GLU 15 | NTc.Cm20 | LYS 34 | - | VdWContact |
| GLU 15 | NTc.Cm20 | LYS 38 | 1.28x28 | Anionic |
| GLU 15 | NTc.Cm20 | LYS 38 | 1.28x28 | HBAcceptor |
| GLU 15 | NTc.Cm20 | LYS 38 | 1.28x28 | VdWContact |
| CYS 16 | NTc.Cm19 | CYS 32 | - | HBAcceptor |
| CYS 16 | NTc.Cm19 | CYS 32 | - | VdWContact |
| PHE 18 | NTc.Cm17 | CYS 32 | - | Hydrophobic |
| PHE 18 | NTc.Cm17 | CYS 32 | - | VdWContact |
| PHE 18 | NTc.Cm17 | CYS 277 | - | Hydrophobic |
| PHE 18 | NTc.Cm17 | THR 280 | 7.28x27 | Hydrophobic |
| THR 21 | NTc.Cm14 | TYR 28 | - | HBDonor |
| THR 21 | NTc.Cm14 | TYR 28 | - | VdWContact |
| TYR 23 | NTc.Cm12 | PHE 24 | - | Hydrophobic |
| TYR 23 | NTc.Cm12 | PHE 24 | - | VdWContact |
| ILE 25 | NTc.Cm10 | PHE 24 | - | Hydrophobic |
| ILE 25 | NTc.Cm10 | PHE 24 | - | VdWContact |
| ARG 29 | NTc.Cm6 | THR 22 | - | VdWContact |
| ASN 37 | cxb1.1 | GLU 184 | - | HBDonor |
| ASN 37 | cxb1.1 | GLU 184 | - | VdWContact |
| ASN 37 | cxb1.1 | TYR 193 | - | VdWContact |
| SER 38 | cxb1.2 | PHE 194 | - | HBDonor |
| SER 38 | cxb1.2 | PHE 194 | - | VdWContact |
| GLN 39 | cxb1.5 | ASN 199 | 5.35x36 | HBDonor |
| GLN 39 | cxb1.5 | ASN 199 | 5.35x36 | VdWContact |
| SER 41 | cxb1.7 | GLN 269 | 6.61x61 | VdWContact |
| SER 41 | cxb1.7 | GLU 270 | 6.62x62 | VdWContact |
| SER 41 | cxb1.7 | SER 275 | - | VdWContact |
| VAL 46 | cxb1.15 | PRO 31 | - | Hydrophobic |
| THR 49 | B1.2 | TYR 26 | - | Hydrophobic |
| HIS 53 | B1.6 | TYR 26 | - | Hydrophobic |
| HIS 53 | B1.6 | TYR 26 | - | VdWContact |
| SER 54 | B1.7 | PRO 31 | - | VdWContact |
| VAL 55 | b1b2.4 | TYR 26 | - | Hydrophobic |
| VAL 55 | b1b2.4 | TYR 26 | - | VdWContact |
| VAL 55 | b1b2.4 | GLY 29 | - | VdWContact |
| CYS 56 | b1b2.6 | GLY 29 | - | HBDonor |
| CYS 56 | b1b2.6 | GLY 29 | - | VdWContact |
| CYS 56 | b1b2.6 | PRO 31 | - | VdWContact |
