Predicted complex interactions
CCL15_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 22 | NTc.Cm31 | LYS 38 | 1.28x28 | Hydrophobic |
| VAL 22 | NTc.Cm31 | LYS 38 | 1.28x28 | VdWContact |
| VAL 22 | NTc.Cm31 | VAL 187 | - | Hydrophobic |
| VAL 22 | NTc.Cm31 | VAL 187 | - | VdWContact |
| LEU 23 | NTc.Cm30 | ALA 42 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm30 | ALA 42 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm30 | ALA 102 | 2.64x64 | VdWContact |
| LEU 23 | NTc.Cm30 | ALA 103 | 2.65x65 | Hydrophobic |
| LEU 23 | NTc.Cm30 | ALA 103 | 2.65x65 | VdWContact |
| ASN 24 | NTc.Cm29 | SER 101 | 2.63x63 | VdWContact |
| ASN 24 | NTc.Cm29 | ASN 104 | 2.66x66 | HBDonor |
| ASN 24 | NTc.Cm29 | ASN 104 | 2.66x66 | VdWContact |
| ASN 24 | NTc.Cm29 | VAL 187 | - | VdWContact |
| ASN 24 | NTc.Cm29 | TYR 188 | - | HBDonor |
| ASN 24 | NTc.Cm29 | TYR 188 | - | VdWContact |
| ASN 24 | NTc.Cm29 | VAL 189 | - | Hydrophobic |
| ASN 24 | NTc.Cm29 | VAL 189 | - | VdWContact |
| SER 25 | NTc.Cm28 | LEU 45 | 1.35x35 | VdWContact |
| PHE 26 | NTc.Cm27 | TRP 98 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 98 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 120 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 120 | 3.32x32 | VdWContact |
| HIS 27 | NTc.Cm26 | ASP 284 | 7.32x31 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ASP 284 | 7.32x31 | VdWContact |
| HIS 27 | NTc.Cm26 | THR 287 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | THR 287 | 7.35x34 | VdWContact |
| HIS 27 | NTc.Cm26 | GLN 288 | 7.36x35 | HBAcceptor |
| HIS 27 | NTc.Cm26 | GLN 288 | 7.36x35 | Hydrophobic |
| HIS 27 | NTc.Cm26 | GLN 288 | 7.36x35 | VdWContact |
| PHE 28 | NTc.Cm25 | LYS 38 | 1.28x28 | Hydrophobic |
| PHE 28 | NTc.Cm25 | LYS 38 | 1.28x28 | VdWContact |
| PHE 28 | NTc.Cm25 | VAL 189 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | VAL 189 | - | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 34 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | VAL 37 | 1.27x27 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 38 | 1.28x28 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 38 | 1.28x28 | VdWContact |
| ALA 29 | NTc.Cm24 | ASP 284 | 7.32x31 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ASP 284 | 7.32x31 | VdWContact |
| ALA 30 | NTc.Cm23 | LYS 34 | - | HBAcceptor |
| ALA 30 | NTc.Cm23 | LYS 34 | - | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 32 | - | VdWContact |
| ASP 31 | NTc.Cm22 | HIS 33 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | HIS 33 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 34 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 34 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 38 | 1.28x28 | Anionic |
| ASP 31 | NTc.Cm22 | LYS 38 | 1.28x28 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 38 | 1.28x28 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 32 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 32 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 32 | - | VdWContact |
| CYS 32 | NTc.Cm21 | LYS 34 | - | Anionic |
| THR 34 | NTc.Cm19 | CYS 32 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 277 | - | Hydrophobic |
| SER 35 | NTc.Cm18 | TYR 28 | - | HBDonor |
| SER 35 | NTc.Cm18 | TYR 28 | - | VdWContact |
| ILE 37 | NTc.Cm16 | PHE 24 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | PHE 24 | - | VdWContact |
| GLN 39 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| GLN 39 | NTc.Cm14 | PHE 24 | - | VdWContact |
| PRO 42 | NTc.Cm11 | PHE 24 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | PHE 24 | - | VdWContact |
| PHE 50 | NTc.Cm3 | GLU 184 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | GLU 184 | - | VdWContact |
| PHE 50 | NTc.Cm3 | ASP 185 | - | VdWContact |
| GLU 51 | NTc.Cm2 | LYS 180 | - | Anionic |
| GLU 51 | NTc.Cm2 | LYS 180 | - | VdWContact |
| GLU 51 | NTc.Cm2 | GLN 182 | - | HBAcceptor |
| GLU 51 | NTc.Cm2 | GLN 182 | - | VdWContact |
| GLU 51 | NTc.Cm2 | TYR 193 | - | VdWContact |
| SER 54 | CX.5 | PRO 192 | 45.52x52 | HBDonor |
| SER 54 | CX.5 | PRO 192 | 45.52x52 | VdWContact |
| SER 54 | CX.5 | PHE 194 | - | HBAcceptor |
| SER 54 | CX.5 | PHE 194 | - | VdWContact |
| SER 54 | CX.5 | ASN 199 | 5.35x36 | HBAcceptor |
| SER 54 | CX.5 | ASN 199 | 5.35x36 | VdWContact |
| GLU 55 | cxb1.1 | PRO 192 | 45.52x52 | Hydrophobic |
| SER 57 | cxb1.5 | ARG 196 | 5.32x33 | HBAcceptor |
| SER 57 | cxb1.5 | ARG 196 | 5.32x33 | VdWContact |
| SER 57 | cxb1.5 | GLN 269 | 6.61x61 | VdWContact |
| LYS 58 | cxb1.6 | GLU 270 | 6.62x62 | Cationic |
| LYS 58 | cxb1.6 | GLU 270 | 6.62x62 | VdWContact |
| ILE 62 | cxb1.11 | PRO 31 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 26 | - | Hydrophobic |
| ARG 69 | B1.4 | ASP 27 | - | Cationic |
| GLN 70 | B1.5 | PRO 31 | - | Hydrophobic |
| GLN 70 | B1.5 | PRO 31 | - | VdWContact |
| GLN 70 | B1.5 | HIS 33 | - | VdWContact |
| GLN 70 | B1.5 | ASP 185 | - | HBDonor |
| GLN 70 | B1.5 | ASP 185 | - | VdWContact |
| VAL 71 | B1.6 | TYR 26 | - | Hydrophobic |
| VAL 71 | B1.6 | TYR 26 | - | VdWContact |
| VAL 71 | B1.6 | GLY 29 | - | VdWContact |
| CYS 72 | B1.7 | GLY 29 | - | HBDonor |
| CYS 72 | B1.7 | GLY 29 | - | VdWContact |
| TYR 90 | b2b3.12 | LYS 183 | - | Hydrophobic |
| TYR 90 | b2b3.12 | LYS 183 | - | VdWContact |
| TYR 90 | b2b3.12 | SER 186 | - | HBDonor |
| TYR 90 | b2b3.12 | SER 186 | - | VdWContact |
| SER 91 | B3.1 | TYR 188 | - | HBAcceptor |
| SER 91 | B3.1 | TYR 188 | - | VdWContact |
| ILE 92 | B3.2 | TYR 188 | - | VdWContact |
