Predicted complex interactions
CCL17_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 69
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm32 | TRP 98 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm32 | TYR 120 | 3.32x32 | CationPi |
| ALA 1 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| ALA 1 | NTc.Cm32 | MET 295 | 7.43x42 | Hydrophobic |
| ARG 2 | NTc.Cm31 | ASN 199 | 5.35x36 | HBDonor |
| ARG 2 | NTc.Cm31 | ASN 199 | 5.35x36 | VdWContact |
| ARG 2 | NTc.Cm31 | TYR 259 | 6.51x51 | VdWContact |
| ARG 2 | NTc.Cm31 | THR 287 | 7.35x34 | Hydrophobic |
| ARG 2 | NTc.Cm31 | GLU 291 | 7.39x38 | HBDonor |
| ARG 2 | NTc.Cm31 | GLU 291 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm30 | GLN 288 | 7.36x35 | HBAcceptor |
| GLY 3 | NTc.Cm30 | GLN 288 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm30 | GLU 291 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm30 | GLU 291 | 7.39x38 | VdWContact |
| THR 4 | NTc.Cm29 | LEU 45 | 1.35x35 | Hydrophobic |
| THR 4 | NTc.Cm29 | TYR 49 | 1.39x39 | Hydrophobic |
| THR 4 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| THR 4 | NTc.Cm29 | ALA 102 | 2.64x64 | Hydrophobic |
| ASN 5 | NTc.Cm28 | CYS 190 | 45.50x50 | HBDonor |
| ASN 5 | NTc.Cm28 | CYS 190 | 45.50x50 | VdWContact |
| VAL 6 | NTc.Cm27 | VAL 37 | 1.27x27 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ASP 284 | 7.32x31 | Hydrophobic |
| VAL 6 | NTc.Cm27 | ASP 284 | 7.32x31 | VdWContact |
| VAL 6 | NTc.Cm27 | THR 287 | 7.35x34 | Hydrophobic |
| VAL 6 | NTc.Cm27 | GLN 288 | 7.36x35 | Hydrophobic |
| GLY 7 | NTc.Cm26 | LYS 34 | - | VdWContact |
| GLY 7 | NTc.Cm26 | LYS 38 | 1.28x28 | VdWContact |
| GLY 7 | NTc.Cm26 | ASP 284 | 7.32x31 | HBDonor |
| GLY 7 | NTc.Cm26 | ASP 284 | 7.32x31 | VdWContact |
| ARG 8 | NTc.Cm25 | GLU 184 | - | Cationic |
| ARG 8 | NTc.Cm25 | GLU 184 | - | HBDonor |
| ARG 8 | NTc.Cm25 | GLU 184 | - | VdWContact |
| ARG 8 | NTc.Cm25 | GLY 191 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm25 | TYR 193 | - | VdWContact |
| GLU 9 | NTc.Cm24 | PRO 31 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | PRO 31 | - | VdWContact |
| GLU 9 | NTc.Cm24 | CYS 32 | - | VdWContact |
| GLU 9 | NTc.Cm24 | HIS 33 | - | HBAcceptor |
| GLU 9 | NTc.Cm24 | HIS 33 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | HIS 33 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 32 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 32 | - | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 32 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | CYS 277 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | PHE 24 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | TYR 26 | - | Hydrophobic |
| ALA 18 | NTc.Cm15 | PHE 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 26 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 26 | - | VdWContact |
| SER 31 | NTc.Cm2 | GLU 184 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLU 184 | - | VdWContact |
| GLU 32 | NTc.Cm1 | LYS 180 | - | Anionic |
| GLU 32 | NTc.Cm1 | LYS 180 | - | HBAcceptor |
| GLU 32 | NTc.Cm1 | LYS 180 | - | VdWContact |
| GLU 32 | NTc.Cm1 | GLN 182 | - | HBAcceptor |
| GLU 32 | NTc.Cm1 | GLN 182 | - | VdWContact |
| GLU 32 | NTc.Cm1 | TYR 193 | - | Hydrophobic |
| GLU 32 | NTc.Cm1 | TYR 193 | - | VdWContact |
| ASP 33 | CX.1 | TYR 193 | - | Hydrophobic |
| ARG 36 | cxb1.2 | GLU 270 | 6.62x62 | Cationic |
| ARG 36 | cxb1.2 | GLU 270 | 6.62x62 | HBDonor |
| ARG 36 | cxb1.2 | GLU 270 | 6.62x62 | VdWContact |
| ARG 47 | B1.2 | PHE 23 | - | VdWContact |
| ARG 47 | B1.2 | ASP 27 | - | Cationic |
| ALA 48 | B1.3 | PRO 31 | - | Hydrophobic |
| ILE 49 | B1.4 | TYR 26 | - | Hydrophobic |
| CYS 50 | B1.5 | GLY 29 | - | HBDonor |
| CYS 50 | B1.5 | GLY 29 | - | VdWContact |
