Predicted complex interactions
CCL18_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 79
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm29 | TYR 120 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm29 | GLU 291 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm29 | GLU 291 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm29 | GLU 291 | 7.39x38 | VdWContact |
| GLN 2 | NTc.Cm28 | THR 287 | 7.35x34 | Hydrophobic |
| GLN 2 | NTc.Cm28 | GLU 291 | 7.39x38 | HBDonor |
| GLN 2 | NTc.Cm28 | GLU 291 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 45 | 1.35x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 49 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TRP 98 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TRP 98 | 2.60x60 | VdWContact |
| VAL 3 | NTc.Cm27 | ALA 102 | 2.64x64 | Hydrophobic |
| VAL 3 | NTc.Cm27 | MET 295 | 7.43x42 | Hydrophobic |
| ASN 6 | NTc.Cm24 | LYS 38 | 1.28x28 | VdWContact |
| ASN 6 | NTc.Cm24 | VAL 189 | - | Hydrophobic |
| LYS 7 | NTc.Cm23 | LYS 34 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 284 | 7.32x31 | Cationic |
| LYS 7 | NTc.Cm23 | ASP 284 | 7.32x31 | HBDonor |
| LYS 7 | NTc.Cm23 | ASP 284 | 7.32x31 | VdWContact |
| GLU 8 | NTc.Cm22 | ARG 8 | - | Anionic |
| GLU 8 | NTc.Cm22 | ARG 8 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | ARG 8 | - | VdWContact |
| GLU 8 | NTc.Cm22 | HIS 33 | - | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 34 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 34 | - | VdWContact |
| GLU 8 | NTc.Cm22 | PHE 35 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | LYS 38 | 1.28x28 | Anionic |
| GLU 8 | NTc.Cm22 | LYS 38 | 1.28x28 | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 31 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 33 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 33 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 32 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 32 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 32 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 32 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 277 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 277 | - | VdWContact |
| LEU 12 | NTc.Cm18 | THR 280 | 7.28x27 | Hydrophobic |
| THR 15 | NTc.Cm15 | TYR 28 | - | VdWContact |
| TRP 17 | NTc.Cm13 | PHE 24 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | ASP 25 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | ASP 25 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 26 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 28 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 26 | - | Hydrophobic |
| LYS 22 | NTc.Cm8 | GLU 19 | - | Cationic |
| LYS 22 | NTc.Cm8 | GLU 19 | - | VdWContact |
| PHE 23 | NTc.Cm7 | GLU 19 | - | VdWContact |
| ASP 26 | NTc.Cm4 | PHE 9 | - | Hydrophobic |
| ASP 26 | NTc.Cm4 | PHE 9 | - | VdWContact |
| SER 31 | CX.5 | GLU 184 | - | HBDonor |
| SER 31 | CX.5 | GLU 184 | - | VdWContact |
| PRO 32 | cxb1.1 | TYR 193 | - | Hydrophobic |
| PRO 32 | cxb1.1 | TYR 193 | - | VdWContact |
| GLN 33 | cxb1.2 | GLU 184 | - | HBDonor |
| GLN 33 | cxb1.2 | GLU 184 | - | VdWContact |
| GLN 33 | cxb1.2 | PRO 192 | 45.52x52 | VdWContact |
| GLN 33 | cxb1.2 | TYR 193 | - | Hydrophobic |
| PRO 35 | cxb1.6 | THR 280 | 7.28x27 | Hydrophobic |
| LYS 36 | cxb1.7 | GLU 270 | 6.62x62 | Cationic |
| LYS 36 | cxb1.7 | GLU 270 | 6.62x62 | HBDonor |
| LYS 36 | cxb1.7 | GLU 270 | 6.62x62 | VdWContact |
| ILE 40 | cxb1.14 | PRO 31 | - | Hydrophobic |
| LEU 42 | cxb1.16 | PHE 9 | - | Hydrophobic |
| ARG 45 | B1.3 | GLY 17 | - | HBDonor |
| ARG 45 | B1.3 | THR 21 | - | HBDonor |
| ARG 45 | B1.3 | THR 21 | - | VdWContact |
| ARG 47 | B1.5 | TYR 26 | - | VdWContact |
| ARG 47 | B1.5 | ASP 27 | - | Cationic |
| GLN 48 | B1.6 | PRO 31 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 26 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 26 | - | VdWContact |
| ILE 49 | B1.7 | GLY 29 | - | VdWContact |
| CYS 50 | b1b2.4 | GLY 29 | - | HBDonor |
| CYS 50 | b1b2.4 | GLY 29 | - | VdWContact |
| ALA 69 | B3.2 | ARG 6 | - | Anionic |
| ALA 69 | B3.2 | ARG 6 | - | HBAcceptor |
| ALA 69 | B3.2 | ARG 6 | - | VdWContact |
