Predicted complex interactions
CCL19_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 291 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 291 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 291 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | TRP 98 | 2.60x60 | Hydrophobic |
| THR 2 | NTc.Cm27 | PRO 192 | 45.52x52 | VdWContact |
| ASN 3 | NTc.Cm26 | THR 287 | 7.35x34 | Hydrophobic |
| ASN 3 | NTc.Cm26 | THR 287 | 7.35x34 | VdWContact |
| ALA 5 | NTc.Cm24 | LYS 34 | - | Hydrophobic |
| ALA 5 | NTc.Cm24 | VAL 37 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 38 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm24 | LYS 38 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm24 | ASP 284 | 7.32x31 | Hydrophobic |
| GLU 6 | NTc.Cm23 | LYS 34 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | LYS 34 | - | VdWContact |
| ASP 7 | NTc.Cm22 | CYS 32 | - | VdWContact |
| ASP 7 | NTc.Cm22 | HIS 33 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | HIS 33 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 34 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 34 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 38 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm22 | LYS 38 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 38 | 1.28x28 | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 32 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 32 | - | HBDonor |
| CYS 8 | NTc.Cm21 | CYS 32 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 32 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 277 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 277 | - | VdWContact |
| THR 13 | NTc.Cm16 | PHE 24 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | PHE 24 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | PHE 24 | - | VdWContact |
| PRO 18 | NTc.Cm11 | THR 22 | - | VdWContact |
| PRO 18 | NTc.Cm11 | PHE 24 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | PHE 24 | - | VdWContact |
| TYR 20 | NTc.Cm9 | VAL 20 | - | HBDonor |
| TYR 20 | NTc.Cm9 | VAL 20 | - | VdWContact |
| TYR 20 | NTc.Cm9 | THR 22 | - | HBAcceptor |
| TYR 20 | NTc.Cm9 | THR 22 | - | VdWContact |
| ILE 21 | NTc.Cm8 | PHE 24 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 26 | - | Hydrophobic |
| LYS 31 | cxb1.1 | GLN 182 | - | HBAcceptor |
| LYS 31 | cxb1.1 | GLN 182 | - | VdWContact |
| LYS 31 | cxb1.1 | TYR 193 | - | VdWContact |
| GLY 33 | cxb1.5 | TYR 193 | - | VdWContact |
| ARG 35 | cxb1.8 | GLN 269 | 6.61x61 | VdWContact |
| ARG 35 | cxb1.8 | GLU 270 | 6.62x62 | Cationic |
| ARG 35 | cxb1.8 | GLU 270 | 6.62x62 | HBDonor |
| ARG 35 | cxb1.8 | GLU 270 | 6.62x62 | VdWContact |
| ARG 35 | cxb1.8 | SER 275 | - | VdWContact |
| VAL 40 | cxb1.15 | PRO 31 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 26 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 26 | - | VdWContact |
| ARG 47 | B1.6 | TYR 26 | - | Hydrophobic |
| ARG 47 | B1.6 | TYR 26 | - | VdWContact |
| GLN 48 | B1.7 | ALA 30 | - | VdWContact |
| GLN 48 | B1.7 | PRO 31 | - | Hydrophobic |
| GLN 48 | B1.7 | PRO 31 | - | VdWContact |
| GLN 48 | B1.7 | HIS 33 | - | VdWContact |
| LEU 49 | b1b2.4 | PHE 24 | - | Hydrophobic |
| LEU 49 | b1b2.4 | PHE 24 | - | VdWContact |
| LEU 49 | b1b2.4 | TYR 26 | - | Hydrophobic |
| CYS 50 | b1b2.6 | GLY 29 | - | HBDonor |
| CYS 50 | b1b2.6 | GLY 29 | - | VdWContact |
