Predicted complex interactions
CCL21_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | GLU 291 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 291 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 291 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | LYS 38 | 1.28x28 | VdWContact |
| GLY 4 | NTc.Cm27 | LYS 34 | - | HBAcceptor |
| GLY 4 | NTc.Cm27 | LYS 34 | - | VdWContact |
| GLY 4 | NTc.Cm27 | ASP 284 | 7.32x31 | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 37 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm26 | VAL 37 | 1.27x27 | VdWContact |
| ALA 5 | NTc.Cm26 | LYS 38 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm26 | LYS 38 | 1.28x28 | VdWContact |
| GLN 6 | NTc.Cm25 | LYS 34 | - | VdWContact |
| GLN 6 | NTc.Cm25 | LYS 38 | 1.28x28 | VdWContact |
| GLN 6 | NTc.Cm25 | GLU 184 | - | HBDonor |
| GLN 6 | NTc.Cm25 | GLU 184 | - | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 32 | - | VdWContact |
| ASP 7 | NTc.Cm24 | HIS 33 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | HIS 33 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LYS 34 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | LYS 34 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 32 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 32 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 32 | - | VdWContact |
| CYS 8 | NTc.Cm23 | LYS 34 | - | Anionic |
| CYS 8 | NTc.Cm23 | LYS 34 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 32 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 277 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 277 | - | VdWContact |
| LEU 10 | NTc.Cm21 | THR 280 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm18 | TYR 28 | - | HBDonor |
| SER 13 | NTc.Cm18 | TYR 28 | - | VdWContact |
| ARG 15 | NTc.Cm16 | PHE 24 | - | Hydrophobic |
| LYS 16 | NTc.Cm15 | PHE 24 | - | VdWContact |
| ILE 17 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PHE 24 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 26 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | TYR 26 | - | VdWContact |
| PRO 18 | NTc.Cm13 | PHE 24 | - | Hydrophobic |
| ARG 26 | NTc.Cm5 | ASP 185 | - | Cationic |
| ARG 26 | NTc.Cm5 | ASP 185 | - | HBDonor |
| ARG 26 | NTc.Cm5 | ASP 185 | - | VdWContact |
| GLU 29 | NTc.Cm2 | LYS 180 | - | Anionic |
| GLU 29 | NTc.Cm2 | LYS 180 | - | HBAcceptor |
| GLU 29 | NTc.Cm2 | LYS 180 | - | VdWContact |
| GLU 29 | NTc.Cm2 | GLN 182 | - | HBAcceptor |
| GLU 29 | NTc.Cm2 | GLN 182 | - | VdWContact |
| GLU 29 | NTc.Cm2 | TYR 193 | - | Hydrophobic |
| LEU 32 | CX.5 | PRO 192 | 45.52x52 | Hydrophobic |
| LEU 32 | CX.5 | ASN 266 | 6.58x58 | HBAcceptor |
| LEU 32 | CX.5 | ASN 266 | 6.58x58 | VdWContact |
| GLY 33 | cxb1.1 | LYS 34 | - | HBAcceptor |
| GLY 33 | cxb1.1 | LYS 34 | - | VdWContact |
| LYS 45 | B1.2 | THR 21 | - | HBDonor |
| LYS 45 | B1.2 | THR 21 | - | VdWContact |
| GLN 48 | B1.5 | TYR 26 | - | Hydrophobic |
| GLN 48 | B1.5 | TYR 26 | - | VdWContact |
| ALA 49 | B1.6 | TYR 26 | - | Hydrophobic |
| ALA 49 | B1.6 | ALA 30 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 31 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 31 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 26 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 26 | - | VdWContact |
| LEU 51 | b1b2.4 | GLY 29 | - | VdWContact |
| CYS 52 | b1b2.6 | GLY 29 | - | HBDonor |
| CYS 52 | b1b2.6 | GLY 29 | - | VdWContact |
| LYS 75 | B3.3 | ASP 185 | - | Cationic |
| LYS 75 | B3.3 | ASP 185 | - | HBDonor |
| LYS 75 | B3.3 | ASP 185 | - | VdWContact |
