Predicted complex interactions
CCL22_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 77
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TYR 49 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm35 | TRP 98 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 98 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 120 | 3.32x32 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 120 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 121 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PRO 192 | 45.52x52 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 202 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm33 | HIS 202 | 5.38x39 | VdWContact |
| TYR 3 | NTc.Cm33 | THR 287 | 7.35x34 | Hydrophobic |
| GLY 4 | NTc.Cm32 | GLN 288 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 291 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm31 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 5 | NTc.Cm31 | ALA 102 | 2.64x64 | Hydrophobic |
| ASN 6 | NTc.Cm30 | CYS 190 | 45.50x50 | HBAcceptor |
| ASN 6 | NTc.Cm30 | CYS 190 | 45.50x50 | HBDonor |
| ASN 6 | NTc.Cm30 | CYS 190 | 45.50x50 | VdWContact |
| MET 7 | NTc.Cm29 | ASP 284 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | THR 287 | 7.35x34 | Hydrophobic |
| MET 7 | NTc.Cm29 | THR 287 | 7.35x34 | VdWContact |
| MET 7 | NTc.Cm29 | GLN 288 | 7.36x35 | Hydrophobic |
| GLU 8 | NTc.Cm28 | LYS 38 | 1.28x28 | Anionic |
| GLU 8 | NTc.Cm28 | LYS 38 | 1.28x28 | HBAcceptor |
| GLU 8 | NTc.Cm28 | LYS 38 | 1.28x28 | VdWContact |
| GLU 8 | NTc.Cm28 | VAL 189 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | VAL 189 | - | VdWContact |
| ASP 9 | NTc.Cm27 | PHE 35 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | PHE 35 | - | VdWContact |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.28x28 | Anionic |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.28x28 | HBAcceptor |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.28x28 | Hydrophobic |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.28x28 | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 31 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | PRO 31 | - | VdWContact |
| VAL 11 | NTc.Cm25 | HIS 33 | - | Hydrophobic |
| CYS 12 | NTc.Cm24 | CYS 32 | - | HBAcceptor |
| CYS 12 | NTc.Cm24 | CYS 32 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 32 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 32 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | GLN 269 | 6.61x61 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 275 | - | VdWContact |
| ARG 14 | NTc.Cm22 | THR 280 | 7.28x27 | VdWContact |
| TYR 19 | NTc.Cm17 | PHE 24 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PHE 24 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ASP 25 | - | HBDonor |
| TYR 19 | NTc.Cm17 | ASP 25 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 26 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | GLU 19 | - | Cationic |
| ARG 24 | NTc.Cm12 | GLU 19 | - | HBDonor |
| ARG 24 | NTc.Cm12 | GLU 19 | - | VdWContact |
| SER 33 | NTc.Cm3 | GLU 184 | - | HBDonor |
| SER 33 | NTc.Cm3 | GLU 184 | - | VdWContact |
| ASP 34 | NTc.Cm2 | GLN 182 | - | HBAcceptor |
| ASP 34 | NTc.Cm2 | GLN 182 | - | VdWContact |
| ASP 34 | NTc.Cm2 | TYR 193 | - | Hydrophobic |
| ARG 38 | cxb1.1 | GLU 270 | 6.62x62 | Cationic |
| ARG 38 | cxb1.1 | GLU 270 | 6.62x62 | HBDonor |
| ARG 38 | cxb1.1 | GLU 270 | 6.62x62 | VdWContact |
| VAL 42 | cxb1.7 | PRO 31 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 26 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 26 | - | VdWContact |
| GLU 50 | B1.2 | PRO 31 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 31 | - | VdWContact |
| GLU 50 | B1.2 | HIS 33 | - | HBAcceptor |
| GLU 50 | B1.2 | HIS 33 | - | VdWContact |
| ILE 51 | B1.3 | TYR 26 | - | Hydrophobic |
| ILE 51 | B1.3 | TYR 26 | - | VdWContact |
| CYS 52 | B1.4 | GLY 29 | - | HBDonor |
| CYS 52 | B1.4 | GLY 29 | - | VdWContact |
