Predicted complex interactions
CCL23_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 23 | NTc.Cm48 | GLN 39 | 1.29x29 | Hydrophobic |
| ASP 24 | NTc.Cm47 | PHE 35 | - | VdWContact |
| ARG 25 | NTc.Cm46 | ASN 104 | 2.66x66 | VdWContact |
| ARG 25 | NTc.Cm46 | GLU 105 | 23.49x49 | Cationic |
| ARG 25 | NTc.Cm46 | GLU 105 | 23.49x49 | HBDonor |
| ARG 25 | NTc.Cm46 | GLU 105 | 23.49x49 | VdWContact |
| ARG 25 | NTc.Cm46 | VAL 187 | - | Hydrophobic |
| ARG 25 | NTc.Cm46 | VAL 187 | - | VdWContact |
| PHE 26 | NTc.Cm45 | LYS 38 | 1.28x28 | Hydrophobic |
| PHE 26 | NTc.Cm45 | ALA 42 | 1.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm45 | ALA 42 | 1.32x32 | VdWContact |
| PHE 26 | NTc.Cm45 | ALA 102 | 2.64x64 | VdWContact |
| PHE 26 | NTc.Cm45 | ALA 103 | 2.65x65 | VdWContact |
| HIS 27 | NTc.Cm44 | SER 101 | 2.63x63 | HBDonor |
| HIS 27 | NTc.Cm44 | SER 101 | 2.63x63 | VdWContact |
| HIS 27 | NTc.Cm44 | ALA 102 | 2.64x64 | VdWContact |
| HIS 27 | NTc.Cm44 | ASN 104 | 2.66x66 | VdWContact |
| HIS 27 | NTc.Cm44 | GLU 105 | 23.49x49 | VdWContact |
| HIS 27 | NTc.Cm44 | TRP 106 | 23.50x50 | HBDonor |
| HIS 27 | NTc.Cm44 | TRP 106 | 23.50x50 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TRP 106 | 23.50x50 | VdWContact |
| HIS 27 | NTc.Cm44 | VAL 187 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | TYR 188 | - | VdWContact |
| HIS 27 | NTc.Cm44 | VAL 189 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | VAL 189 | - | VdWContact |
| ALA 28 | NTc.Cm43 | LYS 38 | 1.28x28 | VdWContact |
| ALA 28 | NTc.Cm43 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 28 | NTc.Cm43 | GLN 288 | 7.36x35 | VdWContact |
| SER 30 | NTc.Cm41 | LYS 34 | - | VdWContact |
| SER 30 | NTc.Cm41 | LYS 38 | 1.28x28 | VdWContact |
| SER 30 | NTc.Cm41 | ASP 284 | 7.32x31 | VdWContact |
| ASP 32 | NTc.Cm39 | CYS 32 | - | VdWContact |
| ASP 32 | NTc.Cm39 | HIS 33 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | HIS 33 | - | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 34 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | LYS 34 | - | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 38 | 1.28x28 | Anionic |
| ASP 32 | NTc.Cm39 | LYS 38 | 1.28x28 | HBAcceptor |
| ASP 32 | NTc.Cm39 | LYS 38 | 1.28x28 | VdWContact |
| CYS 33 | NTc.Cm38 | CYS 32 | - | HBAcceptor |
| CYS 33 | NTc.Cm38 | CYS 32 | - | HBDonor |
| CYS 33 | NTc.Cm38 | CYS 32 | - | Hydrophobic |
| CYS 33 | NTc.Cm38 | CYS 32 | - | VdWContact |
| CYS 33 | NTc.Cm38 | LYS 34 | - | Anionic |
| ILE 35 | NTc.Cm36 | CYS 32 | - | Hydrophobic |
| ILE 35 | NTc.Cm36 | SER 275 | - | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 277 | - | Hydrophobic |
| THR 38 | NTc.Cm33 | TYR 28 | - | VdWContact |
| PRO 39 | NTc.Cm32 | TYR 28 | - | Hydrophobic |
| PRO 39 | NTc.Cm32 | TYR 28 | - | VdWContact |
| ARG 40 | NTc.Cm31 | PHE 23 | - | HBDonor |
| ARG 40 | NTc.Cm31 | PHE 24 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | PHE 24 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | PHE 24 | - | VdWContact |
| ILE 42 | NTc.Cm29 | TYR 26 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | GLU 184 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | ASP 185 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | ASP 185 | - | VdWContact |
| GLU 52 | NTc.Cm19 | LYS 180 | - | Anionic |
| GLU 52 | NTc.Cm19 | LYS 180 | - | VdWContact |
| GLU 52 | NTc.Cm19 | GLN 182 | - | HBAcceptor |
| GLU 52 | NTc.Cm19 | GLN 182 | - | VdWContact |
| GLU 52 | NTc.Cm19 | TYR 193 | - | VdWContact |
| ASN 54 | NTc.Cm17 | TYR 193 | - | Hydrophobic |
| ASN 54 | NTc.Cm17 | TYR 193 | - | VdWContact |
| SER 55 | NTc.Cm16 | PRO 192 | 45.52x52 | HBDonor |
| SER 55 | NTc.Cm16 | PRO 192 | 45.52x52 | VdWContact |
| SER 55 | NTc.Cm16 | TYR 193 | - | VdWContact |
| SER 55 | NTc.Cm16 | PHE 194 | - | HBAcceptor |
| SER 55 | NTc.Cm16 | PHE 194 | - | VdWContact |
| SER 55 | NTc.Cm16 | ASN 199 | 5.35x36 | HBAcceptor |
| SER 55 | NTc.Cm16 | ASN 199 | 5.35x36 | VdWContact |
| GLU 56 | NTc.Cm15 | PRO 192 | 45.52x52 | Hydrophobic |
| GLU 56 | NTc.Cm15 | GLN 269 | 6.61x61 | HBAcceptor |
| GLU 56 | NTc.Cm15 | GLN 269 | 6.61x61 | VdWContact |
| SER 58 | NTc.Cm13 | GLN 269 | 6.61x61 | HBDonor |
| SER 58 | NTc.Cm13 | GLN 269 | 6.61x61 | VdWContact |
| LYS 59 | NTc.Cm12 | GLU 270 | 6.62x62 | Cationic |
| LYS 59 | NTc.Cm12 | GLU 270 | 6.62x62 | VdWContact |
| ILE 63 | NTc.Cm8 | PRO 31 | - | Hydrophobic |
| THR 66 | NTc.Cm5 | TYR 26 | - | Hydrophobic |
| LYS 68 | NTc.Cm3 | GLU 19 | - | Cationic |
| ARG 70 | NTc.Cm1 | PHE 23 | - | CationPi |
| ARG 70 | NTc.Cm1 | PHE 23 | - | VdWContact |
| ARG 70 | NTc.Cm1 | TYR 26 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | TYR 26 | - | VdWContact |
| ARG 71 | CX.1 | PRO 31 | - | Hydrophobic |
| ARG 71 | CX.1 | HIS 33 | - | VdWContact |
| ARG 71 | CX.1 | ASP 185 | - | Cationic |
| ARG 71 | CX.1 | ASP 185 | - | HBDonor |
| ARG 71 | CX.1 | ASP 185 | - | VdWContact |
| PHE 72 | CX.5 | TYR 26 | - | Hydrophobic |
| PHE 72 | CX.5 | TYR 26 | - | VdWContact |
| CYS 73 | cxb1.1 | GLY 29 | - | HBDonor |
| CYS 73 | cxb1.1 | GLY 29 | - | VdWContact |
