Predicted complex interactions
CCL25_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 98 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | TYR 120 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 291 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 291 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | VAL 189 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 37 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 284 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 284 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | THR 287 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 288 | 7.36x35 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 288 | 7.36x35 | VdWContact |
| GLU 5 | NTc.Cm25 | LYS 38 | 1.28x28 | Anionic |
| GLU 5 | NTc.Cm25 | GLU 184 | - | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 32 | - | VdWContact |
| ASP 6 | NTc.Cm24 | HIS 33 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | HIS 33 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 34 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 34 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 32 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 32 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 32 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LYS 34 | - | Anionic |
| LEU 9 | NTc.Cm21 | CYS 32 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 32 | - | VdWContact |
| LEU 9 | NTc.Cm21 | SER 275 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 277 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 277 | - | VdWContact |
| LEU 9 | NTc.Cm21 | THR 280 | 7.28x27 | Hydrophobic |
| HIS 12 | NTc.Cm18 | TYR 26 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | TYR 28 | - | VdWContact |
| VAL 19 | NTc.Cm11 | TYR 26 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 26 | - | VdWContact |
| ARG 22 | NTc.Cm8 | GLU 19 | - | Cationic |
| ARG 22 | NTc.Cm8 | GLU 19 | - | HBDonor |
| ARG 22 | NTc.Cm8 | GLU 19 | - | VdWContact |
| ARG 27 | NTc.Cm3 | GLU 184 | - | Cationic |
| ARG 27 | NTc.Cm3 | GLU 184 | - | HBDonor |
| ARG 27 | NTc.Cm3 | GLU 184 | - | VdWContact |
| ARG 27 | NTc.Cm3 | ASP 185 | - | Cationic |
| ARG 27 | NTc.Cm3 | ASP 185 | - | HBDonor |
| ARG 27 | NTc.Cm3 | ASP 185 | - | VdWContact |
| GLU 30 | CX.1 | LYS 180 | - | Anionic |
| GLU 30 | CX.1 | LYS 180 | - | HBAcceptor |
| GLU 30 | CX.1 | LYS 180 | - | VdWContact |
| GLU 30 | CX.1 | TYR 193 | - | Hydrophobic |
| GLU 30 | CX.1 | TYR 193 | - | VdWContact |
| VAL 31 | CX.5 | TYR 193 | - | VdWContact |
| VAL 31 | CX.5 | PHE 194 | - | HBAcceptor |
| VAL 31 | CX.5 | PHE 194 | - | VdWContact |
| SER 32 | cxb1.1 | PRO 192 | 45.52x52 | VdWContact |
| SER 34 | cxb1.5 | LYS 34 | - | VdWContact |
| SER 34 | cxb1.5 | ASN 266 | 6.58x58 | VdWContact |
| SER 34 | cxb1.5 | GLN 269 | 6.61x61 | HBAcceptor |
| SER 34 | cxb1.5 | GLN 269 | 6.61x61 | VdWContact |
| SER 34 | cxb1.5 | THR 280 | 7.28x27 | VdWContact |
| SER 34 | cxb1.5 | ASP 284 | 7.32x31 | HBDonor |
| SER 34 | cxb1.5 | ASP 284 | 7.32x31 | VdWContact |
| CYS 35 | cxb1.7 | LYS 34 | - | Anionic |
| ASN 36 | cxb1.8 | ASN 266 | 6.58x58 | HBDonor |
| ASN 36 | cxb1.8 | ASN 266 | 6.58x58 | VdWContact |
| ASN 36 | cxb1.8 | GLN 269 | 6.61x61 | HBDonor |
| ASN 36 | cxb1.8 | GLN 269 | 6.61x61 | VdWContact |
| ILE 41 | cxb1.16 | PRO 31 | - | Hydrophobic |
| ARG 49 | b1b2.1 | TYR 26 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 31 | - | Hydrophobic |
| LYS 50 | b1b2.2 | PRO 31 | - | VdWContact |
| LYS 50 | b1b2.2 | ASP 185 | - | Cationic |
| LYS 50 | b1b2.2 | ASP 185 | - | HBDonor |
| LYS 50 | b1b2.2 | ASP 185 | - | VdWContact |
| CYS 52 | b1b2.4 | GLY 29 | - | HBDonor |
| CYS 52 | b1b2.4 | GLY 29 | - | VdWContact |
