Predicted complex interactions
CCL27_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 53
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | THR 287 | 7.35x34 | Hydrophobic |
| PHE 1 | NTc.Cm32 | THR 287 | 7.35x34 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 291 | 7.39x38 | Cationic |
| PHE 1 | NTc.Cm32 | GLU 291 | 7.39x38 | HBDonor |
| PHE 1 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 98 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 98 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 120 | 3.32x32 | Hydrophobic |
| LEU 3 | NTc.Cm30 | SER 101 | 2.63x63 | VdWContact |
| LEU 3 | NTc.Cm30 | ALA 102 | 2.64x64 | Hydrophobic |
| PRO 4 | NTc.Cm29 | VAL 37 | 1.27x27 | Hydrophobic |
| PRO 4 | NTc.Cm29 | GLN 288 | 7.36x35 | VdWContact |
| SER 6 | NTc.Cm27 | LYS 38 | 1.28x28 | HBAcceptor |
| SER 6 | NTc.Cm27 | LYS 38 | 1.28x28 | VdWContact |
| SER 6 | NTc.Cm27 | GLU 184 | - | HBDonor |
| SER 6 | NTc.Cm27 | GLU 184 | - | VdWContact |
| THR 7 | NTc.Cm26 | GLU 184 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | GLU 184 | - | VdWContact |
| THR 7 | NTc.Cm26 | ASP 185 | - | VdWContact |
| ALA 8 | NTc.Cm25 | PRO 31 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | PRO 31 | - | VdWContact |
| ALA 8 | NTc.Cm25 | CYS 32 | - | VdWContact |
| ALA 8 | NTc.Cm25 | HIS 33 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | HIS 33 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 32 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 32 | - | VdWContact |
| THR 11 | NTc.Cm22 | CYS 32 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | SER 275 | - | VdWContact |
| THR 11 | NTc.Cm22 | THR 280 | 7.28x27 | Hydrophobic |
| TYR 14 | NTc.Cm19 | TYR 26 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | TYR 26 | - | PiStacking |
| TYR 14 | NTc.Cm19 | TYR 26 | - | VdWContact |
| LEU 18 | NTc.Cm15 | TYR 26 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | TYR 26 | - | VdWContact |
| LYS 21 | NTc.Cm12 | GLU 19 | - | Cationic |
| LYS 21 | NTc.Cm12 | GLU 19 | - | HBDonor |
| LYS 21 | NTc.Cm12 | GLU 19 | - | VdWContact |
| LEU 22 | NTc.Cm11 | TYR 26 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | TYR 26 | - | VdWContact |
| ASP 35 | cxb1.1 | TYR 193 | - | VdWContact |
| ASP 35 | cxb1.1 | PHE 194 | - | VdWContact |
| GLY 36 | cxb1.2 | PRO 192 | 45.52x52 | VdWContact |
| ASP 37 | cxb1.5 | PRO 192 | 45.52x52 | VdWContact |
| ASP 37 | cxb1.5 | TYR 193 | - | VdWContact |
| LEU 40 | cxb1.8 | GLU 270 | 6.62x62 | Hydrophobic |
| VAL 44 | cxb1.15 | PRO 31 | - | Hydrophobic |
| ARG 50 | B1.2 | TYR 26 | - | VdWContact |
| ARG 50 | B1.2 | ASP 27 | - | Cationic |
| SER 51 | B1.3 | PRO 31 | - | VdWContact |
| ILE 52 | B1.4 | TYR 26 | - | Hydrophobic |
| ILE 52 | B1.4 | GLY 29 | - | VdWContact |
| CYS 53 | B1.5 | GLY 29 | - | HBDonor |
| CYS 53 | B1.5 | GLY 29 | - | VdWContact |
