Predicted complex interactions
CCL28_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm29 | THR 4 | - | HBAcceptor |
| SER 1 | NTc.Cm29 | THR 4 | - | VdWContact |
| SER 1 | NTc.Cm29 | LYS 34 | - | VdWContact |
| GLU 2 | NTc.Cm28 | LEU 2 | - | VdWContact |
| GLU 2 | NTc.Cm28 | VAL 189 | - | Hydrophobic |
| GLU 2 | NTc.Cm28 | VAL 189 | - | VdWContact |
| ALA 3 | NTc.Cm27 | MET 1 | - | VdWContact |
| ALA 3 | NTc.Cm27 | LEU 2 | - | VdWContact |
| ALA 3 | NTc.Cm27 | SER 3 | - | VdWContact |
| ILE 4 | NTc.Cm26 | MET 1 | - | HBDonor |
| ILE 4 | NTc.Cm26 | MET 1 | - | Hydrophobic |
| ILE 4 | NTc.Cm26 | MET 1 | - | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 49 | 1.39x39 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TRP 98 | 2.60x60 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TRP 98 | 2.60x60 | VdWContact |
| LEU 5 | NTc.Cm25 | MET 1 | - | HBDonor |
| LEU 5 | NTc.Cm25 | MET 1 | - | VdWContact |
| LEU 5 | NTc.Cm25 | THR 117 | 3.29x29 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 120 | 3.32x32 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 120 | 3.32x32 | VdWContact |
| LEU 5 | NTc.Cm25 | HIS 121 | 3.33x33 | Hydrophobic |
| LEU 5 | NTc.Cm25 | HIS 121 | 3.33x33 | VdWContact |
| LEU 5 | NTc.Cm25 | ARG 206 | 5.42x43 | VdWContact |
| PRO 6 | NTc.Cm24 | THR 179 | 4.64x65 | Hydrophobic |
| PRO 6 | NTc.Cm24 | CYS 190 | 45.50x50 | VdWContact |
| PRO 6 | NTc.Cm24 | GLY 191 | 45.51x51 | VdWContact |
| PRO 6 | NTc.Cm24 | PRO 192 | 45.52x52 | Hydrophobic |
| PRO 6 | NTc.Cm24 | PRO 192 | 45.52x52 | VdWContact |
| ILE 7 | NTc.Cm23 | SER 3 | - | VdWContact |
| ILE 7 | NTc.Cm23 | PRO 192 | 45.52x52 | VdWContact |
| ALA 8 | NTc.Cm22 | PRO 192 | 45.52x52 | VdWContact |
| SER 9 | NTc.Cm21 | TYR 193 | - | VdWContact |
| SER 10 | NTc.Cm20 | GLU 184 | - | HBDonor |
| SER 10 | NTc.Cm20 | GLU 184 | - | VdWContact |
| CYS 11 | NTc.Cm19 | GLN 182 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 28 | - | HBAcceptor |
| ARG 22 | NTc.Cm8 | TYR 28 | - | VdWContact |
| LEU 23 | NTc.Cm7 | PHE 24 | - | VdWContact |
| LEU 23 | NTc.Cm7 | TYR 26 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 26 | - | VdWContact |
| LEU 23 | NTc.Cm7 | TYR 28 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 28 | - | VdWContact |
| LEU 24 | NTc.Cm6 | TYR 28 | - | VdWContact |
| ARG 26 | NTc.Cm4 | ASP 25 | - | Cationic |
| ARG 26 | NTc.Cm4 | ASP 25 | - | HBDonor |
| ARG 26 | NTc.Cm4 | ASP 25 | - | VdWContact |
| ARG 26 | NTc.Cm4 | ASP 27 | - | Cationic |
| ARG 26 | NTc.Cm4 | ASP 27 | - | VdWContact |
| ARG 26 | NTc.Cm4 | TYR 28 | - | HBDonor |
| ARG 26 | NTc.Cm4 | TYR 28 | - | Hydrophobic |
| ARG 26 | NTc.Cm4 | TYR 28 | - | VdWContact |
| VAL 27 | NTc.Cm3 | TYR 28 | - | Hydrophobic |
| VAL 27 | NTc.Cm3 | TYR 28 | - | VdWContact |
| ASN 28 | NTc.Cm2 | GLY 29 | - | HBAcceptor |
| ASN 28 | NTc.Cm2 | GLY 29 | - | VdWContact |
| ASN 28 | NTc.Cm2 | ALA 30 | - | VdWContact |
| ASN 28 | NTc.Cm2 | PRO 31 | - | HBDonor |
| ASN 28 | NTc.Cm2 | PRO 31 | - | VdWContact |
| MET 29 | NTc.Cm1 | PRO 31 | - | Hydrophobic |
| MET 29 | NTc.Cm1 | PRO 31 | - | VdWContact |
| ARG 31 | CX.5 | ASP 185 | - | Cationic |
| ARG 31 | CX.5 | ASP 185 | - | HBDonor |
| ARG 31 | CX.5 | ASP 185 | - | VdWContact |
| ASP 38 | cxb1.10 | GLN 182 | - | VdWContact |
| ASP 38 | cxb1.10 | LYS 183 | - | VdWContact |
| ASP 40 | cxb1.12 | LYS 180 | - | Anionic |
| VAL 48 | B1.4 | TYR 26 | - | Hydrophobic |
| VAL 48 | B1.4 | TYR 26 | - | VdWContact |
| VAL 48 | B1.4 | ASP 27 | - | VdWContact |
| VAL 48 | B1.4 | TYR 28 | - | Hydrophobic |
| VAL 48 | B1.4 | TYR 28 | - | VdWContact |
| LYS 49 | B1.5 | PHE 9 | - | Hydrophobic |
| LYS 49 | B1.5 | PHE 9 | - | VdWContact |
| LYS 49 | B1.5 | ASP 27 | - | Cationic |
| LYS 49 | B1.5 | ASP 27 | - | HBDonor |
| LYS 49 | B1.5 | ASP 27 | - | Hydrophobic |
| LYS 49 | B1.5 | ASP 27 | - | VdWContact |
| LYS 49 | B1.5 | TYR 28 | - | VdWContact |
| LYS 49 | B1.5 | GLY 29 | - | HBAcceptor |
| LYS 49 | B1.5 | GLY 29 | - | VdWContact |
| LYS 49 | B1.5 | ASN 276 | - | VdWContact |
| ARG 50 | B1.6 | ARG 6 | - | Hydrophobic |
| ARG 50 | B1.6 | SER 7 | - | VdWContact |
| ARG 50 | B1.6 | PHE 9 | - | VdWContact |
| ARG 50 | B1.6 | CYS 32 | - | Hydrophobic |
| ARG 50 | B1.6 | SER 275 | - | VdWContact |
| ARG 50 | B1.6 | ASN 276 | - | HBDonor |
| ARG 50 | B1.6 | ASN 276 | - | VdWContact |
| ARG 50 | B1.6 | CYS 277 | - | HBDonor |
| ARG 50 | B1.6 | CYS 277 | - | VdWContact |
| ARG 50 | B1.6 | GLU 278 | 7.26x25 | HBDonor |
| ARG 50 | B1.6 | GLU 278 | 7.26x25 | VdWContact |
| ARG 50 | B1.6 | SER 279 | 7.27x26 | HBDonor |
| ARG 50 | B1.6 | SER 279 | 7.27x26 | VdWContact |
| ARG 50 | B1.6 | THR 280 | 7.28x27 | HBDonor |
| ARG 50 | B1.6 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 50 | B1.6 | THR 280 | 7.28x27 | VdWContact |
| ARG 51 | B1.7 | ARG 8 | - | Hydrophobic |
| ARG 51 | B1.7 | PHE 9 | - | HBDonor |
| ARG 51 | B1.7 | PHE 9 | - | Hydrophobic |
| ARG 51 | B1.7 | PHE 9 | - | VdWContact |
| ARG 51 | B1.7 | ASP 25 | - | Cationic |
| ARG 51 | B1.7 | ASP 25 | - | VdWContact |
| ARG 51 | B1.7 | TYR 26 | - | Hydrophobic |
| ARG 51 | B1.7 | TYR 26 | - | VdWContact |
| ARG 51 | B1.7 | GLU 270 | 6.62x62 | Cationic |
| ARG 51 | B1.7 | GLU 270 | 6.62x62 | HBDonor |
| ARG 51 | B1.7 | GLU 270 | 6.62x62 | VdWContact |
| ILE 53 | b1b2.6 | TYR 26 | - | Hydrophobic |
| ILE 53 | b1b2.6 | TYR 26 | - | VdWContact |
| LYS 83 | H.5 | LYS 183 | - | HBDonor |
| LYS 83 | H.5 | LYS 183 | - | VdWContact |
