Predicted complex interactions
CCL3_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | TRP 98 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm33 | GLU 291 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm33 | GLU 291 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm32 | PRO 192 | 45.52x52 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TYR 259 | 6.51x51 | Hydrophobic |
| LEU 2 | NTc.Cm32 | TYR 259 | 6.51x51 | VdWContact |
| LEU 2 | NTc.Cm32 | ILE 263 | 6.55x55 | Hydrophobic |
| LEU 2 | NTc.Cm32 | THR 287 | 7.35x34 | Hydrophobic |
| LEU 2 | NTc.Cm32 | GLU 291 | 7.39x38 | HBDonor |
| LEU 2 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| ALA 3 | NTc.Cm31 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | LEU 45 | 1.35x35 | VdWContact |
| ALA 3 | NTc.Cm31 | TYR 49 | 1.39x39 | VdWContact |
| ALA 3 | NTc.Cm31 | GLN 288 | 7.36x35 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLN 288 | 7.36x35 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 291 | 7.39x38 | HBDonor |
| ALA 3 | NTc.Cm31 | GLU 291 | 7.39x38 | Hydrophobic |
| ALA 3 | NTc.Cm31 | GLU 291 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 4 | NTc.Cm30 | TYR 49 | 1.39x39 | Hydrophobic |
| ALA 4 | NTc.Cm30 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ALA 102 | 2.64x64 | Hydrophobic |
| ASP 5 | NTc.Cm29 | CYS 190 | 45.50x50 | HBAcceptor |
| ASP 5 | NTc.Cm29 | CYS 190 | 45.50x50 | VdWContact |
| ASP 5 | NTc.Cm29 | GLY 191 | 45.51x51 | VdWContact |
| THR 6 | NTc.Cm28 | LYS 34 | - | Hydrophobic |
| THR 6 | NTc.Cm28 | VAL 37 | 1.27x27 | Hydrophobic |
| THR 6 | NTc.Cm28 | LYS 38 | 1.28x28 | Hydrophobic |
| THR 6 | NTc.Cm28 | LYS 38 | 1.28x28 | VdWContact |
| THR 6 | NTc.Cm28 | ASP 284 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | GLN 288 | 7.36x35 | HBAcceptor |
| THR 6 | NTc.Cm28 | GLN 288 | 7.36x35 | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 34 | - | VdWContact |
| PRO 7 | NTc.Cm27 | LYS 38 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm26 | LYS 34 | - | HBAcceptor |
| THR 8 | NTc.Cm26 | LYS 34 | - | VdWContact |
| THR 8 | NTc.Cm26 | LYS 38 | 1.28x28 | HBAcceptor |
| THR 8 | NTc.Cm26 | LYS 38 | 1.28x28 | VdWContact |
| THR 8 | NTc.Cm26 | GLU 184 | - | HBDonor |
| THR 8 | NTc.Cm26 | GLU 184 | - | VdWContact |
| THR 8 | NTc.Cm26 | ASP 185 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | PRO 31 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | PRO 31 | - | VdWContact |
| ALA 9 | NTc.Cm25 | CYS 32 | - | VdWContact |
| ALA 9 | NTc.Cm25 | HIS 33 | - | Hydrophobic |
| CYS 10 | NTc.Cm24 | CYS 32 | - | HBAcceptor |
| CYS 10 | NTc.Cm24 | CYS 32 | - | HBDonor |
| CYS 10 | NTc.Cm24 | CYS 32 | - | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 32 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 32 | - | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 277 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | THR 280 | 7.28x27 | Hydrophobic |
| PHE 12 | NTc.Cm22 | THR 280 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm21 | TYR 28 | - | HBDonor |
| SER 13 | NTc.Cm21 | TYR 28 | - | VdWContact |
| ARG 17 | NTc.Cm17 | PHE 24 | - | Hydrophobic |
| ARG 17 | NTc.Cm17 | PHE 24 | - | VdWContact |
| GLN 18 | NTc.Cm16 | PHE 24 | - | VdWContact |
| ILE 19 | NTc.Cm15 | PHE 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm15 | PHE 24 | - | VdWContact |
| ASP 26 | NTc.Cm7 | LYS 183 | - | Anionic |
| ASP 26 | NTc.Cm7 | LYS 183 | - | VdWContact |
| PHE 28 | NTc.Cm5 | GLU 184 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | GLU 184 | - | VdWContact |
| PHE 28 | NTc.Cm5 | ASP 185 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | ASP 185 | - | VdWContact |
| GLU 29 | NTc.Cm4 | LYS 180 | - | Anionic |
| GLU 29 | NTc.Cm4 | LYS 180 | - | VdWContact |
| GLU 29 | NTc.Cm4 | GLN 182 | - | HBAcceptor |
| GLU 29 | NTc.Cm4 | GLN 182 | - | VdWContact |
| GLU 29 | NTc.Cm4 | TYR 193 | - | Hydrophobic |
| GLU 29 | NTc.Cm4 | TYR 193 | - | VdWContact |
| SER 31 | NTc.Cm2 | PRO 192 | 45.52x52 | VdWContact |
| SER 31 | NTc.Cm2 | TYR 193 | - | VdWContact |
| SER 32 | NTc.Cm1 | PRO 192 | 45.52x52 | HBDonor |
| SER 32 | NTc.Cm1 | PRO 192 | 45.52x52 | VdWContact |
| SER 32 | NTc.Cm1 | PHE 194 | - | HBAcceptor |
| SER 32 | NTc.Cm1 | PHE 194 | - | VdWContact |
| SER 32 | NTc.Cm1 | ASN 199 | 5.35x36 | HBAcceptor |
| SER 32 | NTc.Cm1 | ASN 199 | 5.35x36 | VdWContact |
| GLN 33 | CX.1 | PRO 192 | 45.52x52 | Hydrophobic |
| GLN 33 | CX.1 | GLN 269 | 6.61x61 | HBAcceptor |
| GLN 33 | CX.1 | GLN 269 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | GLN 269 | 6.61x61 | VdWContact |
| LYS 36 | cxb1.2 | GLU 270 | 6.62x62 | Cationic |
| LYS 36 | cxb1.2 | GLU 270 | 6.62x62 | VdWContact |
| ILE 40 | cxb1.8 | PRO 31 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 26 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 26 | - | VdWContact |
| GLN 48 | B1.3 | PRO 31 | - | Hydrophobic |
| GLN 48 | B1.3 | HIS 33 | - | VdWContact |
| GLN 48 | B1.3 | ASP 185 | - | HBDonor |
| GLN 48 | B1.3 | ASP 185 | - | VdWContact |
| VAL 49 | B1.4 | TYR 26 | - | Hydrophobic |
| VAL 49 | B1.4 | TYR 26 | - | VdWContact |
| CYS 50 | B1.5 | GLY 29 | - | HBDonor |
| CYS 50 | B1.5 | GLY 29 | - | VdWContact |
