Predicted complex interactions
CCL5_HUMAN + CCR2
SUMMARY
- Chemokine
- CCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 65
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm32 | TYR 49 | 1.39x39 | HBDonor |
| SER 1 | NTc.Cm32 | TYR 49 | 1.39x39 | VdWContact |
| SER 1 | NTc.Cm32 | TRP 98 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm32 | GLU 291 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm31 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TRP 98 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm31 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm31 | PRO 192 | 45.52x52 | VdWContact |
| TYR 3 | NTc.Cm30 | TYR 120 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm30 | HIS 121 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm30 | PRO 192 | 45.52x52 | Hydrophobic |
| TYR 3 | NTc.Cm30 | HIS 202 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm30 | HIS 202 | 5.38x39 | VdWContact |
| TYR 3 | NTc.Cm30 | THR 287 | 7.35x34 | Hydrophobic |
| SER 4 | NTc.Cm29 | GLN 288 | 7.36x35 | HBAcceptor |
| ASP 6 | NTc.Cm27 | PRO 192 | 45.52x52 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 34 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 38 | 1.28x28 | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 38 | 1.28x28 | VdWContact |
| PRO 9 | NTc.Cm24 | PRO 31 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | CYS 32 | - | VdWContact |
| PRO 9 | NTc.Cm24 | HIS 33 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | HIS 33 | - | VdWContact |
| PRO 9 | NTc.Cm24 | ASP 185 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 32 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 32 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 32 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | SER 275 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 277 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | THR 280 | 7.28x27 | Hydrophobic |
| ALA 13 | NTc.Cm20 | TYR 28 | - | Hydrophobic |
| ILE 15 | NTc.Cm18 | PHE 24 | - | Hydrophobic |
| ILE 15 | NTc.Cm18 | PHE 24 | - | VdWContact |
| ARG 17 | NTc.Cm16 | PHE 24 | - | Hydrophobic |
| PRO 18 | NTc.Cm15 | PHE 24 | - | VdWContact |
| LEU 19 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 26 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | PHE 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | PHE 24 | - | VdWContact |
| SER 31 | NTc.Cm2 | GLU 184 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLU 184 | - | VdWContact |
| LYS 33 | CX.1 | GLU 184 | - | Cationic |
| LYS 33 | CX.1 | GLU 184 | - | HBDonor |
| LYS 33 | CX.1 | GLU 184 | - | VdWContact |
| LYS 33 | CX.1 | TYR 193 | - | Hydrophobic |
| LYS 33 | CX.1 | TYR 193 | - | VdWContact |
| SER 35 | cxb1.1 | GLN 269 | 6.61x61 | HBAcceptor |
| SER 35 | cxb1.1 | GLN 269 | 6.61x61 | VdWContact |
| SER 35 | cxb1.1 | GLU 270 | 6.62x62 | VdWContact |
| VAL 40 | cxb1.8 | PRO 31 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 26 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 26 | - | Hydrophobic |
| ARG 47 | B1.2 | TYR 26 | - | VdWContact |
| ARG 47 | B1.2 | ASP 27 | - | Cationic |
| ARG 47 | B1.2 | ASP 27 | - | HBDonor |
| ARG 47 | B1.2 | ASP 27 | - | VdWContact |
| GLN 48 | B1.3 | PRO 31 | - | Hydrophobic |
| GLN 48 | B1.3 | HIS 33 | - | HBAcceptor |
| GLN 48 | B1.3 | HIS 33 | - | VdWContact |
| VAL 49 | B1.4 | TYR 26 | - | Hydrophobic |
| VAL 49 | B1.4 | TYR 26 | - | VdWContact |
| VAL 49 | B1.4 | GLY 29 | - | VdWContact |
| CYS 50 | B1.5 | GLY 29 | - | HBDonor |
| CYS 50 | B1.5 | GLY 29 | - | VdWContact |
