Predicted complex interactions
CX3CL1_HUMAN + CCR2
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 67
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | THR 117 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm37 | TYR 120 | 3.32x32 | CationPi |
| GLN 1 | NTc.Cm37 | TYR 120 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm37 | TYR 120 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm37 | HIS 121 | 3.33x33 | Hydrophobic |
| GLN 1 | NTc.Cm37 | HIS 121 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm37 | THR 179 | 4.64x65 | HBDonor |
| GLN 1 | NTc.Cm37 | THR 179 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm37 | GLU 291 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm37 | GLU 291 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | LEU 45 | 1.35x35 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 49 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 49 | 1.39x39 | VdWContact |
| HIS 2 | NTc.Cm36 | TRP 98 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TRP 98 | 2.60x60 | VdWContact |
| HIS 2 | NTc.Cm36 | MET 295 | 7.43x42 | Hydrophobic |
| HIS 2 | NTc.Cm36 | MET 295 | 7.43x42 | VdWContact |
| HIS 3 | NTc.Cm35 | PRO 192 | 45.52x52 | Hydrophobic |
| HIS 3 | NTc.Cm35 | THR 287 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | GLU 291 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 291 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | LYS 38 | 1.28x28 | Hydrophobic |
| VAL 5 | NTc.Cm33 | LYS 38 | 1.28x28 | VdWContact |
| THR 6 | NTc.Cm32 | VAL 189 | - | Hydrophobic |
| THR 6 | NTc.Cm32 | GLY 191 | 45.51x51 | VdWContact |
| LYS 7 | NTc.Cm31 | ASP 36 | - | Cationic |
| LYS 7 | NTc.Cm31 | ASP 36 | - | HBDonor |
| LYS 7 | NTc.Cm31 | ASP 36 | - | VdWContact |
| LYS 7 | NTc.Cm31 | VAL 37 | 1.27x27 | VdWContact |
| LYS 7 | NTc.Cm31 | LYS 38 | 1.28x28 | Hydrophobic |
| LYS 7 | NTc.Cm31 | LYS 38 | 1.28x28 | VdWContact |
| CYS 8 | NTc.Cm30 | LYS 34 | - | VdWContact |
| ASN 9 | NTc.Cm29 | HIS 33 | - | VdWContact |
| ASN 9 | NTc.Cm29 | LYS 34 | - | HBAcceptor |
| ASN 9 | NTc.Cm29 | LYS 34 | - | VdWContact |
| ILE 10 | NTc.Cm28 | PRO 31 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | PRO 31 | - | VdWContact |
| ILE 10 | NTc.Cm28 | CYS 32 | - | VdWContact |
| ILE 10 | NTc.Cm28 | HIS 33 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | CYS 32 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 32 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 32 | - | VdWContact |
| THR 11 | NTc.Cm27 | LYS 34 | - | VdWContact |
| LYS 14 | NTc.Cm24 | TYR 28 | - | HBDonor |
| LYS 14 | NTc.Cm24 | TYR 28 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | TYR 28 | - | VdWContact |
| LYS 18 | NTc.Cm20 | PHE 24 | - | VdWContact |
| ILE 19 | NTc.Cm19 | PHE 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | PHE 24 | - | VdWContact |
| GLN 31 | NTc.Cm7 | ASP 185 | - | HBDonor |
| GLN 31 | NTc.Cm7 | ASP 185 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLU 184 | - | VdWContact |
| ALA 32 | NTc.Cm6 | TYR 193 | - | Hydrophobic |
| SER 33 | NTc.Cm5 | GLU 184 | - | HBDonor |
| SER 33 | NTc.Cm5 | GLU 184 | - | VdWContact |
| ILE 40 | CX.3 | PRO 31 | - | Hydrophobic |
| ARG 47 | cxb1.8 | TYR 26 | - | CationPi |
| ARG 47 | cxb1.8 | TYR 26 | - | Hydrophobic |
| ARG 47 | cxb1.8 | TYR 26 | - | VdWContact |
| LEU 48 | cxb1.10 | PRO 31 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PRO 31 | - | VdWContact |
| LEU 48 | cxb1.10 | HIS 33 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 26 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 26 | - | VdWContact |
| CYS 50 | cxb1.14 | GLY 29 | - | HBDonor |
| CYS 50 | cxb1.14 | GLY 29 | - | VdWContact |
| CYS 50 | cxb1.14 | PRO 31 | - | VdWContact |
