Predicted complex interactions
CXCL1_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 69
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 120 | 3.32x32 | CationPi |
| ALA 1 | NTc.Cm42 | TYR 120 | 3.32x32 | HBDonor |
| ALA 1 | NTc.Cm42 | TYR 120 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 120 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm42 | GLU 291 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm42 | GLU 291 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm42 | GLU 291 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm41 | THR 287 | 7.35x34 | VdWContact |
| SER 2 | NTc.Cm41 | GLU 291 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm41 | GLU 291 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm40 | TRP 98 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm40 | CYS 190 | 45.50x50 | VdWContact |
| ALA 4 | NTc.Cm39 | ALA 102 | 2.64x64 | Hydrophobic |
| THR 5 | NTc.Cm38 | VAL 189 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | VAL 189 | - | VdWContact |
| ARG 8 | NTc.Cm35 | ASN 266 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | GLN 269 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm35 | GLN 269 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 8 | NTc.Cm35 | THR 280 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 283 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 284 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 284 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 284 | 7.32x31 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 31 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | PRO 31 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 32 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 32 | - | VdWContact |
| GLN 10 | NTc.Cm33 | ASP 185 | - | HBDonor |
| GLN 10 | NTc.Cm33 | ASP 185 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 32 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | SER 275 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 277 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 277 | - | VdWContact |
| LEU 12 | NTc.Cm31 | THR 280 | 7.28x27 | Hydrophobic |
| GLN 13 | NTc.Cm30 | TYR 28 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | ASP 25 | - | VdWContact |
| LEU 15 | NTc.Cm28 | TYR 26 | - | VdWContact |
| LEU 15 | NTc.Cm28 | TYR 28 | - | Hydrophobic |
| GLY 17 | NTc.Cm26 | PHE 24 | - | VdWContact |
| ILE 18 | NTc.Cm25 | PHE 24 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | PHE 24 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 26 | - | Hydrophobic |
| LYS 21 | NTc.Cm22 | GLU 19 | - | Cationic |
| LYS 21 | NTc.Cm22 | GLU 19 | - | HBDonor |
| LYS 21 | NTc.Cm22 | GLU 19 | - | VdWContact |
| ASN 22 | NTc.Cm21 | TYR 26 | - | HBDonor |
| LYS 29 | NTc.Cm14 | ASP 185 | - | Cationic |
| LYS 29 | NTc.Cm14 | ASP 185 | - | HBDonor |
| LYS 29 | NTc.Cm14 | ASP 185 | - | VdWContact |
| PRO 33 | NTc.Cm10 | PRO 192 | 45.52x52 | VdWContact |
| PRO 33 | NTc.Cm10 | TYR 193 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | TYR 193 | - | VdWContact |
| HIS 34 | NTc.Cm9 | GLU 184 | - | VdWContact |
| HIS 34 | NTc.Cm9 | PRO 192 | 45.52x52 | VdWContact |
| ILE 41 | NTc.Cm2 | PRO 31 | - | Hydrophobic |
| LEU 44 | CX.4 | TYR 26 | - | Hydrophobic |
| LEU 44 | CX.4 | TYR 26 | - | VdWContact |
| ARG 48 | cxb1.5 | ASP 27 | - | Cationic |
| ARG 48 | cxb1.5 | ASP 27 | - | HBDonor |
| ARG 48 | cxb1.5 | ASP 27 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 31 | - | Hydrophobic |
| LYS 49 | cxb1.6 | PRO 31 | - | VdWContact |
| ALA 50 | cxb1.8 | TYR 26 | - | Hydrophobic |
| ALA 50 | cxb1.8 | GLY 29 | - | VdWContact |
| CYS 51 | cxb1.10 | GLY 29 | - | HBDonor |
| CYS 51 | cxb1.10 | GLY 29 | - | VdWContact |
| CYS 51 | cxb1.10 | PRO 31 | - | VdWContact |
