Predicted complex interactions
CXCL10_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 69
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm29 | THR 117 | 3.29x29 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 120 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 120 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | HIS 121 | 3.33x33 | Hydrophobic |
| VAL 1 | NTc.Cm29 | GLU 291 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm29 | GLU 291 | 7.39x38 | HBDonor |
| VAL 1 | NTc.Cm29 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 49 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TRP 98 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 291 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | MET 295 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm28 | MET 295 | 7.43x42 | VdWContact |
| LEU 3 | NTc.Cm27 | THR 287 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm27 | THR 287 | 7.35x34 | VdWContact |
| LEU 3 | NTc.Cm27 | GLU 291 | 7.39x38 | HBDonor |
| LEU 3 | NTc.Cm27 | GLU 291 | 7.39x38 | VdWContact |
| ARG 5 | NTc.Cm25 | LYS 38 | 1.28x28 | Hydrophobic |
| ARG 5 | NTc.Cm25 | ALA 42 | 1.32x32 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 102 | 2.64x64 | HBDonor |
| ARG 5 | NTc.Cm25 | ALA 102 | 2.64x64 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 103 | 2.65x65 | HBDonor |
| ARG 5 | NTc.Cm25 | ALA 103 | 2.65x65 | VdWContact |
| ARG 5 | NTc.Cm25 | ASN 104 | 2.66x66 | VdWContact |
| THR 6 | NTc.Cm24 | GLU 184 | - | VdWContact |
| THR 6 | NTc.Cm24 | VAL 189 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | LYS 34 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | LYS 34 | - | VdWContact |
| ARG 8 | NTc.Cm22 | LYS 34 | - | HBAcceptor |
| ARG 8 | NTc.Cm22 | LYS 34 | - | VdWContact |
| ARG 8 | NTc.Cm22 | GLN 269 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm22 | GLN 269 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | THR 280 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 8 | NTc.Cm22 | THR 280 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 283 | 7.31x30 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 284 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 284 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 284 | 7.32x31 | VdWContact |
| THR 10 | NTc.Cm20 | CYS 32 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 32 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 32 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | SER 275 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 277 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 277 | - | VdWContact |
| ILE 12 | NTc.Cm18 | THR 280 | 7.28x27 | Hydrophobic |
| SER 15 | NTc.Cm15 | TYR 28 | - | HBDonor |
| SER 15 | NTc.Cm15 | TYR 28 | - | VdWContact |
| ALA 32 | CX.5 | TYR 193 | - | VdWContact |
| SER 33 | cxb1.1 | TYR 193 | - | VdWContact |
| GLN 34 | cxb1.2 | PRO 192 | 45.52x52 | HBDonor |
| GLN 34 | cxb1.2 | PRO 192 | 45.52x52 | Hydrophobic |
| GLN 34 | cxb1.2 | PRO 192 | 45.52x52 | VdWContact |
| GLN 34 | cxb1.2 | PHE 194 | - | Hydrophobic |
| GLN 34 | cxb1.2 | ASN 199 | 5.35x36 | VdWContact |
| PHE 35 | cxb1.5 | PRO 192 | 45.52x52 | Hydrophobic |
| PHE 35 | cxb1.5 | PRO 192 | 45.52x52 | VdWContact |
| ARG 38 | cxb1.8 | GLU 270 | 6.62x62 | Cationic |
| ILE 42 | cxb1.15 | PRO 31 | - | Hydrophobic |
| LYS 47 | B1.4 | THR 21 | - | VdWContact |
| LYS 47 | B1.4 | PHE 23 | - | Hydrophobic |
| LYS 47 | B1.4 | PHE 23 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 31 | - | Hydrophobic |
| LYS 51 | b1b2.4 | PRO 31 | - | VdWContact |
| ARG 52 | b1b2.6 | GLY 29 | - | VdWContact |
| CYS 53 | b1b2.7 | GLY 29 | - | HBDonor |
| CYS 53 | b1b2.7 | GLY 29 | - | VdWContact |
| CYS 53 | b1b2.7 | PRO 31 | - | VdWContact |
