Predicted complex interactions
CXCL13_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | LEU 45 | 1.35x35 | Hydrophobic |
| VAL 1 | NTc.Cm32 | LEU 45 | 1.35x35 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 49 | 1.39x39 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 49 | 1.39x39 | VdWContact |
| VAL 1 | NTc.Cm32 | TRP 98 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TRP 98 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm32 | ALA 102 | 2.64x64 | Hydrophobic |
| VAL 1 | NTc.Cm32 | GLU 291 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 291 | 7.39x38 | HBDonor |
| VAL 1 | NTc.Cm32 | GLU 291 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 98 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TRP 98 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 120 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 120 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm31 | GLU 291 | 7.39x38 | HBDonor |
| LEU 2 | NTc.Cm31 | GLU 291 | 7.39x38 | VdWContact |
| GLU 3 | NTc.Cm30 | ARG 206 | 5.42x43 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 206 | 5.42x43 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 206 | 5.42x43 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 259 | 6.51x51 | HBAcceptor |
| GLU 3 | NTc.Cm30 | TYR 259 | 6.51x51 | Hydrophobic |
| GLU 3 | NTc.Cm30 | TYR 259 | 6.51x51 | VdWContact |
| GLU 3 | NTc.Cm30 | ILE 263 | 6.55x55 | Hydrophobic |
| GLU 3 | NTc.Cm30 | ILE 263 | 6.55x55 | VdWContact |
| VAL 4 | NTc.Cm29 | THR 287 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLN 288 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLN 288 | 7.36x35 | VdWContact |
| VAL 4 | NTc.Cm29 | GLU 291 | 7.39x38 | HBDonor |
| VAL 4 | NTc.Cm29 | GLU 291 | 7.39x38 | VdWContact |
| TYR 5 | NTc.Cm28 | VAL 189 | - | Hydrophobic |
| TYR 5 | NTc.Cm28 | PRO 192 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | HIS 121 | 3.33x33 | HBAcceptor |
| TYR 6 | NTc.Cm27 | HIS 121 | 3.33x33 | Hydrophobic |
| TYR 6 | NTc.Cm27 | HIS 121 | 3.33x33 | VdWContact |
| TYR 6 | NTc.Cm27 | THR 179 | 4.64x65 | HBAcceptor |
| TYR 6 | NTc.Cm27 | THR 179 | 4.64x65 | VdWContact |
| TYR 6 | NTc.Cm27 | PRO 192 | 45.52x52 | Hydrophobic |
| TYR 6 | NTc.Cm27 | PRO 192 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | PHE 194 | - | Hydrophobic |
| TYR 6 | NTc.Cm27 | PHE 194 | - | VdWContact |
| TYR 6 | NTc.Cm27 | HIS 202 | 5.38x39 | Hydrophobic |
| THR 7 | NTc.Cm26 | ILE 263 | 6.55x55 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASN 266 | 6.58x58 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASN 266 | 6.58x58 | VdWContact |
| THR 7 | NTc.Cm26 | THR 287 | 7.35x34 | Hydrophobic |
| THR 7 | NTc.Cm26 | THR 287 | 7.35x34 | VdWContact |
| SER 8 | NTc.Cm25 | ASN 266 | 6.58x58 | HBDonor |
| SER 8 | NTc.Cm25 | ASN 266 | 6.58x58 | VdWContact |
| SER 8 | NTc.Cm25 | GLN 269 | 6.61x61 | HBAcceptor |
| SER 8 | NTc.Cm25 | GLN 269 | 6.61x61 | VdWContact |
| LEU 9 | NTc.Cm24 | LYS 34 | - | HBAcceptor |
| LEU 9 | NTc.Cm24 | LYS 34 | - | VdWContact |
| LEU 9 | NTc.Cm24 | ASN 266 | 6.58x58 | VdWContact |
| LEU 9 | NTc.Cm24 | GLN 269 | 6.61x61 | Hydrophobic |
| LEU 9 | NTc.Cm24 | GLN 269 | 6.61x61 | VdWContact |
| LEU 9 | NTc.Cm24 | THR 280 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm24 | THR 280 | 7.28x27 | VdWContact |
| LEU 9 | NTc.Cm24 | LEU 283 | 7.31x30 | Hydrophobic |
| LEU 9 | NTc.Cm24 | ASP 284 | 7.32x31 | VdWContact |
| ARG 12 | NTc.Cm21 | PRO 31 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | PRO 31 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 32 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 32 | - | VdWContact |
| ARG 12 | NTc.Cm21 | ASP 185 | - | Cationic |
| ARG 12 | NTc.Cm21 | ASP 185 | - | HBDonor |
| ARG 12 | NTc.Cm21 | ASP 185 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 32 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | SER 275 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 277 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | THR 280 | 7.28x27 | Hydrophobic |
| GLN 15 | NTc.Cm18 | TYR 28 | - | VdWContact |
| GLN 30 | NTc.Cm3 | ASP 185 | - | HBDonor |
| GLN 30 | NTc.Cm3 | ASP 185 | - | VdWContact |
| PRO 33 | CX.1 | GLN 182 | - | VdWContact |
| ARG 34 | CX.4 | TYR 193 | - | VdWContact |
| GLY 35 | CX.5 | TYR 193 | - | VdWContact |
| ASN 36 | cxb1.1 | GLU 184 | - | HBDonor |
| ASN 36 | cxb1.1 | GLU 184 | - | VdWContact |
| ASN 36 | cxb1.1 | VAL 189 | - | VdWContact |
| ASN 36 | cxb1.1 | GLY 191 | 45.51x51 | VdWContact |
| ASN 36 | cxb1.1 | PRO 192 | 45.52x52 | VdWContact |
| ASN 36 | cxb1.1 | TYR 193 | - | Hydrophobic |
| PRO 39 | cxb1.6 | ARG 196 | 5.32x33 | Hydrophobic |
| ARG 40 | cxb1.7 | GLU 270 | 6.62x62 | Cationic |
| ILE 44 | cxb1.14 | PRO 31 | - | Hydrophobic |
| LYS 47 | B1.1 | TYR 26 | - | CationPi |
| ILE 52 | B1.6 | ALA 30 | - | VdWContact |
| ILE 52 | B1.6 | PRO 31 | - | Hydrophobic |
| VAL 53 | B1.7 | TYR 26 | - | Hydrophobic |
| CYS 54 | b1b2.4 | GLY 29 | - | HBDonor |
| CYS 54 | b1b2.4 | GLY 29 | - | VdWContact |
