Predicted complex interactions
CXCL16_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 98
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | TYR 120 | 3.32x32 | CationPi |
| ASN 1 | NTc.Cm56 | GLU 291 | 7.39x38 | Cationic |
| ASN 1 | NTc.Cm56 | GLU 291 | 7.39x38 | VdWContact |
| ASN 1 | NTc.Cm56 | MET 295 | 7.43x42 | VdWContact |
| GLU 2 | NTc.Cm55 | HIS 121 | 3.33x33 | Hydrophobic |
| GLU 2 | NTc.Cm55 | HIS 121 | 3.33x33 | VdWContact |
| GLU 2 | NTc.Cm55 | HIS 202 | 5.38x39 | HBAcceptor |
| GLU 2 | NTc.Cm55 | HIS 202 | 5.38x39 | Hydrophobic |
| GLU 2 | NTc.Cm55 | HIS 202 | 5.38x39 | VdWContact |
| GLU 2 | NTc.Cm55 | ARG 206 | 5.42x43 | Anionic |
| GLU 2 | NTc.Cm55 | ARG 206 | 5.42x43 | HBAcceptor |
| GLU 2 | NTc.Cm55 | ARG 206 | 5.42x43 | VdWContact |
| GLU 2 | NTc.Cm55 | TYR 259 | 6.51x51 | HBDonor |
| GLU 2 | NTc.Cm55 | TYR 259 | 6.51x51 | VdWContact |
| GLU 2 | NTc.Cm55 | GLU 291 | 7.39x38 | HBDonor |
| GLU 2 | NTc.Cm55 | GLU 291 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm54 | GLU 291 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm54 | GLU 291 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm53 | GLU 291 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm53 | GLU 291 | 7.39x38 | VdWContact |
| THR 6 | NTc.Cm51 | LYS 38 | 1.28x28 | VdWContact |
| THR 6 | NTc.Cm51 | LEU 45 | 1.35x35 | Hydrophobic |
| THR 6 | NTc.Cm51 | ALA 102 | 2.64x64 | HBDonor |
| THR 6 | NTc.Cm51 | ALA 102 | 2.64x64 | Hydrophobic |
| THR 6 | NTc.Cm51 | ALA 102 | 2.64x64 | VdWContact |
| GLY 7 | NTc.Cm50 | VAL 37 | 1.27x27 | VdWContact |
| GLY 7 | NTc.Cm50 | LYS 38 | 1.28x28 | VdWContact |
| TYR 10 | NTc.Cm47 | ASN 199 | 5.35x36 | HBAcceptor |
| TYR 10 | NTc.Cm47 | ASN 199 | 5.35x36 | VdWContact |
| TYR 10 | NTc.Cm47 | ASN 266 | 6.58x58 | Hydrophobic |
| TYR 10 | NTc.Cm47 | ASN 266 | 6.58x58 | VdWContact |
| TYR 10 | NTc.Cm47 | THR 267 | 6.59x59 | HBDonor |
| TYR 10 | NTc.Cm47 | THR 267 | 6.59x59 | VdWContact |
| TYR 10 | NTc.Cm47 | ASP 284 | 7.32x31 | HBDonor |
| TYR 10 | NTc.Cm47 | ASP 284 | 7.32x31 | VdWContact |
| GLY 12 | NTc.Cm45 | ASN 199 | 5.35x36 | HBAcceptor |
| GLY 12 | NTc.Cm45 | ASN 199 | 5.35x36 | VdWContact |
| ARG 14 | NTc.Cm43 | GLU 184 | - | Cationic |
| ARG 14 | NTc.Cm43 | GLU 184 | - | HBDonor |
| ARG 14 | NTc.Cm43 | GLU 184 | - | VdWContact |
| ARG 14 | NTc.Cm43 | TYR 193 | - | Hydrophobic |
| SER 16 | NTc.Cm41 | GLN 182 | - | HBDonor |
| SER 16 | NTc.Cm41 | GLN 182 | - | VdWContact |
| SER 17 | NTc.Cm40 | LYS 183 | - | HBDonor |
| SER 17 | NTc.Cm40 | LYS 183 | - | VdWContact |
| ARG 34 | NTc.Cm23 | TYR 28 | - | Hydrophobic |
| ARG 34 | NTc.Cm23 | TYR 28 | - | VdWContact |
| ARG 34 | NTc.Cm23 | GLU 270 | 6.62x62 | Cationic |
| ALA 35 | NTc.Cm22 | TYR 28 | - | VdWContact |
| TYR 36 | NTc.Cm21 | PRO 31 | - | Hydrophobic |
| TYR 36 | NTc.Cm21 | CYS 32 | - | HBAcceptor |
| TYR 36 | NTc.Cm21 | CYS 32 | - | VdWContact |
| HIS 37 | NTc.Cm20 | CYS 32 | - | Hydrophobic |
| HIS 37 | NTc.Cm20 | CYS 32 | - | VdWContact |
| HIS 37 | NTc.Cm20 | LYS 34 | - | Hydrophobic |
| HIS 37 | NTc.Cm20 | LYS 34 | - | VdWContact |
| HIS 37 | NTc.Cm20 | CYS 277 | - | VdWContact |
| ARG 38 | NTc.Cm19 | CYS 32 | - | HBDonor |
| ARG 38 | NTc.Cm19 | CYS 32 | - | VdWContact |
| ARG 38 | NTc.Cm19 | HIS 33 | - | Hydrophobic |
| ARG 38 | NTc.Cm19 | HIS 33 | - | VdWContact |
| ARG 38 | NTc.Cm19 | LYS 34 | - | HBAcceptor |
| ARG 38 | NTc.Cm19 | LYS 34 | - | VdWContact |
| ARG 38 | NTc.Cm19 | PHE 35 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | PHE 35 | - | Hydrophobic |
| LEU 40 | NTc.Cm17 | PHE 35 | - | VdWContact |
| LEU 40 | NTc.Cm17 | LYS 38 | 1.28x28 | Hydrophobic |
| LEU 40 | NTc.Cm17 | LYS 38 | 1.28x28 | VdWContact |
| TYR 41 | NTc.Cm16 | LYS 38 | 1.28x28 | VdWContact |
| TYR 41 | NTc.Cm16 | GLU 184 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | GLU 184 | - | VdWContact |
| TYR 41 | NTc.Cm16 | ASP 185 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | ASP 185 | - | VdWContact |
| TYR 41 | NTc.Cm16 | VAL 187 | - | Hydrophobic |
| TYR 41 | NTc.Cm16 | VAL 187 | - | VdWContact |
| TYR 41 | NTc.Cm16 | VAL 189 | - | Hydrophobic |
| TYR 42 | NTc.Cm15 | GLU 184 | - | VdWContact |
| ARG 44 | NTc.Cm13 | LYS 34 | - | VdWContact |
| ARG 44 | NTc.Cm13 | THR 280 | 7.28x27 | VdWContact |
| ARG 44 | NTc.Cm13 | ASP 284 | 7.32x31 | Cationic |
| ARG 44 | NTc.Cm13 | ASP 284 | 7.32x31 | HBDonor |
| ARG 44 | NTc.Cm13 | ASP 284 | 7.32x31 | VdWContact |
| GLN 46 | NTc.Cm11 | GLN 269 | 6.61x61 | HBDonor |
| GLN 46 | NTc.Cm11 | GLN 269 | 6.61x61 | VdWContact |
| GLN 46 | NTc.Cm11 | SER 275 | - | VdWContact |
| LEU 48 | NTc.Cm9 | GLU 270 | 6.62x62 | VdWContact |
| SER 49 | NTc.Cm8 | ARG 196 | 5.32x33 | VdWContact |
| SER 49 | NTc.Cm8 | GLU 270 | 6.62x62 | VdWContact |
| TRP 50 | NTc.Cm7 | ARG 196 | 5.32x33 | Hydrophobic |
| TRP 50 | NTc.Cm7 | ARG 196 | 5.32x33 | PiCation |
| TRP 50 | NTc.Cm7 | ARG 196 | 5.32x33 | VdWContact |
| GLY 55 | NTc.Cm2 | ASP 185 | - | VdWContact |
| ASN 56 | NTc.Cm1 | ASP 185 | - | HBDonor |
| ASN 56 | NTc.Cm1 | ASP 185 | - | VdWContact |
| LYS 57 | CX.1 | ASP 185 | - | HBDonor |
| LYS 57 | CX.1 | ASP 185 | - | VdWContact |
| LYS 57 | CX.1 | SER 186 | - | HBDonor |
| LYS 57 | CX.1 | SER 186 | - | VdWContact |
