Predicted complex interactions
CXCL4_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 3 | NTc.Cm38 | ARG 196 | 5.32x33 | Anionic |
| GLU 3 | NTc.Cm38 | ARG 196 | 5.32x33 | HBAcceptor |
| GLU 3 | NTc.Cm38 | ARG 196 | 5.32x33 | VdWContact |
| GLU 4 | NTc.Cm37 | GLU 270 | 6.62x62 | HBDonor |
| GLU 4 | NTc.Cm37 | GLU 270 | 6.62x62 | Hydrophobic |
| GLU 4 | NTc.Cm37 | GLU 270 | 6.62x62 | VdWContact |
| GLU 4 | NTc.Cm37 | SER 275 | - | HBAcceptor |
| GLU 4 | NTc.Cm37 | SER 275 | - | VdWContact |
| ASP 5 | NTc.Cm36 | ARG 196 | 5.32x33 | Anionic |
| ASP 5 | NTc.Cm36 | ARG 196 | 5.32x33 | HBAcceptor |
| ASP 5 | NTc.Cm36 | ARG 196 | 5.32x33 | VdWContact |
| GLY 6 | NTc.Cm35 | GLN 269 | 6.61x61 | VdWContact |
| ASP 7 | NTc.Cm34 | ASN 199 | 5.35x36 | HBAcceptor |
| ASP 7 | NTc.Cm34 | ASN 199 | 5.35x36 | VdWContact |
| ASP 7 | NTc.Cm34 | ASN 266 | 6.58x58 | HBAcceptor |
| ASP 7 | NTc.Cm34 | ASN 266 | 6.58x58 | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 34 | - | VdWContact |
| LEU 8 | NTc.Cm33 | ASN 266 | 6.58x58 | HBDonor |
| LEU 8 | NTc.Cm33 | ASN 266 | 6.58x58 | Hydrophobic |
| LEU 8 | NTc.Cm33 | ASN 266 | 6.58x58 | VdWContact |
| LEU 8 | NTc.Cm33 | ASP 284 | 7.32x31 | VdWContact |
| LEU 8 | NTc.Cm33 | THR 287 | 7.35x34 | Hydrophobic |
| LEU 8 | NTc.Cm33 | THR 287 | 7.35x34 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 284 | 7.32x31 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 31 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | CYS 32 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 32 | - | VdWContact |
| LEU 11 | NTc.Cm30 | HIS 33 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | CYS 32 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | SER 275 | - | VdWContact |
| VAL 13 | NTc.Cm28 | THR 280 | 7.28x27 | Hydrophobic |
| LYS 14 | NTc.Cm27 | TYR 28 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | SER 275 | - | VdWContact |
| GLN 18 | NTc.Cm23 | PHE 24 | - | Hydrophobic |
| VAL 19 | NTc.Cm22 | TYR 26 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | GLU 19 | - | Cationic |
| ARG 20 | NTc.Cm21 | GLU 19 | - | HBDonor |
| ARG 20 | NTc.Cm21 | GLU 19 | - | VdWContact |
| ARG 20 | NTc.Cm21 | VAL 20 | - | HBDonor |
| ARG 20 | NTc.Cm21 | VAL 20 | - | VdWContact |
| ARG 20 | NTc.Cm21 | THR 22 | - | HBDonor |
| ARG 20 | NTc.Cm21 | THR 22 | - | VdWContact |
| ARG 20 | NTc.Cm21 | PHE 24 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | PHE 24 | - | VdWContact |
| ARG 22 | NTc.Cm19 | GLU 19 | - | Cationic |
| ARG 22 | NTc.Cm19 | GLU 19 | - | HBDonor |
| ARG 22 | NTc.Cm19 | GLU 19 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 26 | - | HBDonor |
| HIS 23 | NTc.Cm18 | TYR 26 | - | VdWContact |
| ALA 32 | NTc.Cm9 | TYR 193 | - | VdWContact |
| GLY 33 | NTc.Cm8 | GLU 184 | - | VdWContact |
| GLY 33 | NTc.Cm8 | TYR 193 | - | VdWContact |
| PRO 34 | NTc.Cm7 | GLU 184 | - | VdWContact |
| PRO 34 | NTc.Cm7 | VAL 189 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | GLY 191 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | PRO 192 | 45.52x52 | VdWContact |
| PRO 34 | NTc.Cm7 | TYR 193 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | TYR 193 | - | VdWContact |
| ILE 42 | CX.4 | PRO 31 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 26 | - | Hydrophobic |
| ARG 49 | cxb1.10 | TYR 26 | - | VdWContact |
| ARG 49 | cxb1.10 | ASP 27 | - | Cationic |
| ARG 49 | cxb1.10 | ASP 27 | - | HBDonor |
| ARG 49 | cxb1.10 | ASP 27 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 31 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 31 | - | VdWContact |
| ILE 51 | cxb1.14 | TYR 26 | - | Hydrophobic |
| ILE 51 | cxb1.14 | TYR 26 | - | VdWContact |
| ILE 51 | cxb1.14 | GLY 29 | - | VdWContact |
| ILE 51 | cxb1.14 | PRO 31 | - | VdWContact |
| CYS 52 | cxb1.15 | GLY 29 | - | HBDonor |
| CYS 52 | cxb1.15 | GLY 29 | - | VdWContact |
