Predicted complex interactions
CXCL5_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | TYR 49 | 1.39x39 | HBAcceptor |
| ALA 1 | NTc.Cm48 | TYR 49 | 1.39x39 | HBDonor |
| ALA 1 | NTc.Cm48 | TYR 49 | 1.39x39 | VdWContact |
| ALA 1 | NTc.Cm48 | GLU 291 | 7.39x38 | Hydrophobic |
| ALA 1 | NTc.Cm48 | GLU 291 | 7.39x38 | VdWContact |
| ALA 1 | NTc.Cm48 | MET 295 | 7.43x42 | VdWContact |
| GLY 2 | NTc.Cm47 | GLU 291 | 7.39x38 | HBDonor |
| GLY 2 | NTc.Cm47 | GLU 291 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 98 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 120 | 3.32x32 | Hydrophobic |
| ALA 5 | NTc.Cm44 | LEU 45 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | LEU 45 | 1.35x35 | VdWContact |
| ALA 6 | NTc.Cm43 | TRP 98 | 2.60x60 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TRP 98 | 2.60x60 | VdWContact |
| ALA 6 | NTc.Cm43 | SER 101 | 2.63x63 | VdWContact |
| VAL 7 | NTc.Cm42 | VAL 189 | - | Hydrophobic |
| VAL 7 | NTc.Cm42 | VAL 189 | - | VdWContact |
| LEU 8 | NTc.Cm41 | LYS 38 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LYS 38 | 1.28x28 | VdWContact |
| LEU 8 | NTc.Cm41 | ALA 42 | 1.32x32 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 45 | 1.35x35 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ALA 102 | 2.64x64 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ALA 102 | 2.64x64 | VdWContact |
| ARG 9 | NTc.Cm40 | VAL 37 | 1.27x27 | VdWContact |
| GLU 10 | NTc.Cm39 | LYS 38 | 1.28x28 | Anionic |
| GLU 10 | NTc.Cm39 | LYS 38 | 1.28x28 | HBAcceptor |
| GLU 10 | NTc.Cm39 | LYS 38 | 1.28x28 | Hydrophobic |
| GLU 10 | NTc.Cm39 | LYS 38 | 1.28x28 | VdWContact |
| LEU 11 | NTc.Cm38 | LYS 34 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | LYS 34 | - | VdWContact |
| ARG 12 | NTc.Cm37 | LYS 34 | - | HBAcceptor |
| ARG 12 | NTc.Cm37 | LYS 34 | - | VdWContact |
| ARG 12 | NTc.Cm37 | ASN 266 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | GLN 269 | 6.61x61 | HBDonor |
| ARG 12 | NTc.Cm37 | GLN 269 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 12 | NTc.Cm37 | LEU 283 | 7.31x30 | HBDonor |
| ARG 12 | NTc.Cm37 | LEU 283 | 7.31x30 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 284 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 284 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 284 | 7.32x31 | VdWContact |
| CYS 13 | NTc.Cm36 | LYS 34 | - | HBAcceptor |
| CYS 13 | NTc.Cm36 | LYS 34 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 32 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 32 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 32 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 277 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 277 | - | VdWContact |
| LEU 16 | NTc.Cm33 | THR 280 | 7.28x27 | Hydrophobic |
| THR 19 | NTc.Cm30 | TYR 26 | - | HBDonor |
| THR 19 | NTc.Cm30 | TYR 26 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | TYR 26 | - | VdWContact |
| THR 19 | NTc.Cm30 | GLY 29 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 26 | - | VdWContact |
| VAL 22 | NTc.Cm27 | TYR 26 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 26 | - | HBDonor |
| HIS 23 | NTc.Cm26 | TYR 26 | - | VdWContact |
| LYS 25 | NTc.Cm24 | GLU 19 | - | Cationic |
| LYS 25 | NTc.Cm24 | GLU 19 | - | HBDonor |
| LYS 25 | NTc.Cm24 | GLU 19 | - | VdWContact |
| ILE 35 | NTc.Cm14 | TYR 193 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLU 184 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLY 191 | 45.51x51 | VdWContact |
| PRO 37 | NTc.Cm12 | PRO 192 | 45.52x52 | VdWContact |
| PRO 37 | NTc.Cm12 | TYR 193 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | TYR 193 | - | VdWContact |
| SER 40 | NTc.Cm9 | ARG 196 | 5.32x33 | VdWContact |
| SER 40 | NTc.Cm9 | ASN 199 | 5.35x36 | HBAcceptor |
| SER 40 | NTc.Cm9 | ASN 199 | 5.35x36 | VdWContact |
| LYS 41 | NTc.Cm8 | GLU 270 | 6.62x62 | Cationic |
| LYS 41 | NTc.Cm8 | GLU 270 | 6.62x62 | HBDonor |
| LYS 41 | NTc.Cm8 | GLU 270 | 6.62x62 | VdWContact |
| VAL 45 | NTc.Cm4 | PRO 31 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | TYR 26 | - | Hydrophobic |
| LYS 52 | cxb1.1 | ASP 25 | - | Cationic |
| LYS 52 | cxb1.1 | ASP 25 | - | HBDonor |
| LYS 52 | cxb1.1 | ASP 25 | - | VdWContact |
| LYS 52 | cxb1.1 | ASP 27 | - | Cationic |
| LYS 52 | cxb1.1 | ASP 27 | - | HBDonor |
| LYS 52 | cxb1.1 | ASP 27 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 31 | - | Hydrophobic |
| GLU 53 | cxb1.2 | PRO 31 | - | VdWContact |
| ILE 54 | cxb1.5 | TYR 26 | - | Hydrophobic |
| ILE 54 | cxb1.5 | TYR 26 | - | VdWContact |
| ILE 54 | cxb1.5 | PRO 31 | - | VdWContact |
| CYS 55 | cxb1.6 | GLY 29 | - | HBDonor |
| CYS 55 | cxb1.6 | GLY 29 | - | VdWContact |
