Predicted complex interactions
CXCL6_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 76
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | TRP 98 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm48 | GLU 291 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm48 | GLU 291 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm48 | MET 295 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm47 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TRP 98 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 120 | 3.32x32 | VdWContact |
| VAL 3 | NTc.Cm46 | PRO 192 | 45.52x52 | Hydrophobic |
| VAL 3 | NTc.Cm46 | TYR 259 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm46 | THR 287 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLU 291 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm45 | TYR 49 | 1.39x39 | HBAcceptor |
| SER 4 | NTc.Cm45 | TYR 49 | 1.39x39 | VdWContact |
| SER 4 | NTc.Cm45 | GLU 291 | 7.39x38 | HBDonor |
| SER 4 | NTc.Cm45 | GLU 291 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | TRP 98 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | VAL 189 | - | Hydrophobic |
| VAL 6 | NTc.Cm43 | GLY 191 | 45.51x51 | VdWContact |
| LEU 7 | NTc.Cm42 | VAL 37 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LYS 38 | 1.28x28 | VdWContact |
| LEU 7 | NTc.Cm42 | GLN 288 | 7.36x35 | Hydrophobic |
| LEU 7 | NTc.Cm42 | GLN 288 | 7.36x35 | VdWContact |
| THR 8 | NTc.Cm41 | LYS 38 | 1.28x28 | Hydrophobic |
| GLU 9 | NTc.Cm40 | HIS 33 | - | VdWContact |
| GLU 9 | NTc.Cm40 | LYS 34 | - | HBAcceptor |
| GLU 9 | NTc.Cm40 | LYS 34 | - | Hydrophobic |
| GLU 9 | NTc.Cm40 | LYS 34 | - | VdWContact |
| LEU 10 | NTc.Cm39 | ASP 284 | 7.32x31 | Hydrophobic |
| LEU 10 | NTc.Cm39 | THR 287 | 7.35x34 | Hydrophobic |
| ARG 11 | NTc.Cm38 | LYS 34 | - | HBAcceptor |
| ARG 11 | NTc.Cm38 | LYS 34 | - | VdWContact |
| ARG 11 | NTc.Cm38 | ASN 266 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASN 266 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | GLN 269 | 6.61x61 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 274 | - | HBDonor |
| ARG 11 | NTc.Cm38 | LEU 274 | - | VdWContact |
| ARG 11 | NTc.Cm38 | THR 280 | 7.28x27 | HBDonor |
| ARG 11 | NTc.Cm38 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 11 | NTc.Cm38 | THR 280 | 7.28x27 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 283 | 7.31x30 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 284 | 7.32x31 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 284 | 7.32x31 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 284 | 7.32x31 | VdWContact |
| THR 13 | NTc.Cm36 | CYS 32 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 32 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 32 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 277 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 277 | - | VdWContact |
| LEU 15 | NTc.Cm34 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 16 | NTc.Cm33 | ASP 27 | - | Cationic |
| ARG 16 | NTc.Cm33 | ASP 27 | - | HBDonor |
| ARG 16 | NTc.Cm33 | ASP 27 | - | VdWContact |
| ARG 16 | NTc.Cm33 | GLY 29 | - | VdWContact |
| THR 18 | NTc.Cm31 | TYR 28 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | TYR 28 | - | VdWContact |
| THR 18 | NTc.Cm31 | GLY 29 | - | HBAcceptor |
| THR 18 | NTc.Cm31 | GLY 29 | - | VdWContact |
| VAL 21 | NTc.Cm28 | TYR 28 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | ASP 185 | - | VdWContact |
| GLY 35 | NTc.Cm14 | TYR 193 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLU 184 | - | VdWContact |
| PRO 36 | NTc.Cm13 | TYR 193 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | TYR 193 | - | VdWContact |
| GLN 37 | NTc.Cm12 | GLU 184 | - | HBDonor |
| GLN 37 | NTc.Cm12 | GLU 184 | - | VdWContact |
| LYS 40 | NTc.Cm9 | GLU 270 | 6.62x62 | Cationic |
| VAL 44 | NTc.Cm5 | PRO 31 | - | Hydrophobic |
| LYS 51 | CX.5 | ASP 25 | - | Cationic |
| LYS 51 | CX.5 | ASP 25 | - | HBDonor |
| LYS 51 | CX.5 | ASP 25 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 31 | - | Hydrophobic |
| VAL 53 | cxb1.2 | TYR 28 | - | Hydrophobic |
| VAL 53 | cxb1.2 | TYR 28 | - | VdWContact |
| CYS 54 | cxb1.5 | GLY 29 | - | HBDonor |
| CYS 54 | cxb1.5 | GLY 29 | - | VdWContact |
