Predicted complex interactions
CXCL7_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 23 | NTc.Cm40 | LYS 38 | 1.28x28 | HBAcceptor |
| LEU 23 | NTc.Cm40 | LYS 38 | 1.28x28 | VdWContact |
| LEU 23 | NTc.Cm40 | VAL 187 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | VAL 187 | - | VdWContact |
| TYR 24 | NTc.Cm39 | LYS 38 | 1.28x28 | Hydrophobic |
| TYR 24 | NTc.Cm39 | LYS 38 | 1.28x28 | VdWContact |
| TYR 24 | NTc.Cm39 | GLN 39 | 1.29x29 | Hydrophobic |
| ALA 25 | NTc.Cm38 | LYS 38 | 1.28x28 | HBAcceptor |
| ALA 25 | NTc.Cm38 | LYS 38 | 1.28x28 | VdWContact |
| ALA 25 | NTc.Cm38 | ASP 185 | - | Hydrophobic |
| ALA 25 | NTc.Cm38 | ASP 185 | - | VdWContact |
| GLU 26 | NTc.Cm37 | HIS 33 | - | HBAcceptor |
| GLU 26 | NTc.Cm37 | HIS 33 | - | VdWContact |
| GLU 26 | NTc.Cm37 | LYS 34 | - | Anionic |
| GLU 26 | NTc.Cm37 | LYS 34 | - | HBAcceptor |
| GLU 26 | NTc.Cm37 | LYS 34 | - | VdWContact |
| LEU 27 | NTc.Cm36 | VAL 37 | 1.27x27 | Hydrophobic |
| LEU 27 | NTc.Cm36 | ASP 284 | 7.32x31 | Hydrophobic |
| ARG 28 | NTc.Cm35 | LYS 34 | - | HBAcceptor |
| ARG 28 | NTc.Cm35 | LYS 34 | - | VdWContact |
| ARG 28 | NTc.Cm35 | ASN 266 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | THR 280 | 7.28x27 | HBDonor |
| ARG 28 | NTc.Cm35 | THR 280 | 7.28x27 | Hydrophobic |
| ARG 28 | NTc.Cm35 | THR 280 | 7.28x27 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 283 | 7.31x30 | HBDonor |
| ARG 28 | NTc.Cm35 | LEU 283 | 7.31x30 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 284 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 284 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 284 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | THR 287 | 7.35x34 | VdWContact |
| CYS 29 | NTc.Cm34 | LYS 34 | - | HBAcceptor |
| CYS 29 | NTc.Cm34 | LYS 34 | - | VdWContact |
| MET 30 | NTc.Cm33 | PRO 31 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | CYS 32 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 32 | - | VdWContact |
| MET 30 | NTc.Cm33 | HIS 33 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | HIS 33 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 32 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 277 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 277 | - | VdWContact |
| ILE 32 | NTc.Cm31 | THR 280 | 7.28x27 | Hydrophobic |
| LYS 33 | NTc.Cm30 | TYR 28 | - | VdWContact |
| THR 35 | NTc.Cm28 | TYR 26 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | TYR 26 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | TYR 26 | - | VdWContact |
| LYS 41 | NTc.Cm22 | GLU 19 | - | Cationic |
| LYS 41 | NTc.Cm22 | GLU 19 | - | HBDonor |
| LYS 41 | NTc.Cm22 | GLU 19 | - | VdWContact |
| GLY 52 | NTc.Cm11 | GLU 184 | - | VdWContact |
| THR 53 | NTc.Cm10 | GLU 184 | - | HBDonor |
| THR 53 | NTc.Cm10 | GLU 184 | - | VdWContact |
| THR 53 | NTc.Cm10 | VAL 189 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | GLY 191 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | TYR 193 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | TYR 193 | - | VdWContact |
| ILE 61 | NTc.Cm2 | PRO 31 | - | Hydrophobic |
| LEU 64 | CX.4 | TYR 26 | - | Hydrophobic |
| LYS 69 | cxb1.6 | PRO 31 | - | Hydrophobic |
| LYS 69 | cxb1.6 | PRO 31 | - | VdWContact |
| ILE 70 | cxb1.8 | TYR 26 | - | Hydrophobic |
| ILE 70 | cxb1.8 | TYR 26 | - | VdWContact |
| ILE 70 | cxb1.8 | PRO 31 | - | VdWContact |
| CYS 71 | cxb1.10 | GLY 29 | - | HBDonor |
| CYS 71 | cxb1.10 | GLY 29 | - | VdWContact |
