Predicted complex interactions
CXCL8_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 67
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 7 | NTc.Cm27 | ASP 185 | - | Cationic |
| ARG 7 | NTc.Cm27 | ASP 185 | - | Hydrophobic |
| ARG 7 | NTc.Cm27 | ASP 185 | - | VdWContact |
| ALA 9 | NTc.Cm25 | LYS 38 | 1.28x28 | HBAcceptor |
| ALA 9 | NTc.Cm25 | LYS 38 | 1.28x28 | VdWContact |
| ALA 9 | NTc.Cm25 | VAL 187 | - | Hydrophobic |
| ALA 9 | NTc.Cm25 | VAL 187 | - | VdWContact |
| ALA 9 | NTc.Cm25 | VAL 189 | - | Hydrophobic |
| LYS 10 | NTc.Cm24 | ASP 36 | - | Cationic |
| LYS 10 | NTc.Cm24 | ASP 36 | - | HBDonor |
| LYS 10 | NTc.Cm24 | ASP 36 | - | VdWContact |
| LYS 10 | NTc.Cm24 | LYS 38 | 1.28x28 | Hydrophobic |
| LYS 10 | NTc.Cm24 | LYS 38 | 1.28x28 | VdWContact |
| ARG 13 | NTc.Cm21 | LYS 34 | - | HBAcceptor |
| ARG 13 | NTc.Cm21 | LYS 34 | - | Hydrophobic |
| ARG 13 | NTc.Cm21 | LYS 34 | - | VdWContact |
| ARG 13 | NTc.Cm21 | ASP 284 | 7.32x31 | Cationic |
| ARG 13 | NTc.Cm21 | ASP 284 | 7.32x31 | HBDonor |
| ARG 13 | NTc.Cm21 | ASP 284 | 7.32x31 | Hydrophobic |
| ARG 13 | NTc.Cm21 | ASP 284 | 7.32x31 | VdWContact |
| ARG 13 | NTc.Cm21 | THR 287 | 7.35x34 | HBDonor |
| ARG 13 | NTc.Cm21 | THR 287 | 7.35x34 | VdWContact |
| CYS 14 | NTc.Cm20 | LYS 34 | - | VdWContact |
| GLN 15 | NTc.Cm19 | PRO 31 | - | Hydrophobic |
| GLN 15 | NTc.Cm19 | CYS 32 | - | HBAcceptor |
| GLN 15 | NTc.Cm19 | CYS 32 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 32 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | THR 280 | 7.28x27 | Hydrophobic |
| ILE 17 | NTc.Cm17 | THR 280 | 7.28x27 | VdWContact |
| LYS 18 | NTc.Cm16 | ASP 27 | - | HBDonor |
| LYS 18 | NTc.Cm16 | ASP 27 | - | VdWContact |
| LYS 18 | NTc.Cm16 | TYR 28 | - | Hydrophobic |
| LYS 18 | NTc.Cm16 | TYR 28 | - | VdWContact |
| TYR 20 | NTc.Cm14 | PHE 24 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | PHE 24 | - | VdWContact |
| TYR 20 | NTc.Cm14 | ASP 25 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | ASP 25 | - | VdWContact |
| LYS 22 | NTc.Cm12 | ASP 25 | - | Cationic |
| PHE 24 | NTc.Cm10 | PHE 24 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | PHE 24 | - | PiStacking |
| PHE 24 | NTc.Cm10 | PHE 24 | - | VdWContact |
| PHE 28 | NTc.Cm6 | THR 22 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | PHE 24 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | PHE 24 | - | PiStacking |
| ARG 33 | NTc.Cm1 | ASP 185 | - | Cationic |
| ARG 33 | NTc.Cm1 | ASP 185 | - | HBDonor |
| ARG 33 | NTc.Cm1 | ASP 185 | - | VdWContact |
| GLY 38 | cxb1.2 | GLU 184 | - | VdWContact |
| GLY 38 | cxb1.2 | TYR 193 | - | VdWContact |
| PRO 39 | cxb1.5 | GLU 184 | - | VdWContact |
| PRO 39 | cxb1.5 | PRO 192 | 45.52x52 | Hydrophobic |
| PRO 39 | cxb1.5 | PRO 192 | 45.52x52 | VdWContact |
| PRO 39 | cxb1.5 | TYR 193 | - | Hydrophobic |
| PRO 39 | cxb1.5 | TYR 193 | - | VdWContact |
| HIS 40 | cxb1.6 | GLU 184 | - | HBDonor |
| HIS 40 | cxb1.6 | GLU 184 | - | VdWContact |
| ILE 47 | cxb1.16 | PRO 31 | - | Hydrophobic |
| LEU 50 | B1.3 | PHE 24 | - | Hydrophobic |
| ARG 54 | B1.7 | PHE 24 | - | VdWContact |
| ARG 54 | B1.7 | TYR 26 | - | Hydrophobic |
| ARG 54 | B1.7 | TYR 26 | - | VdWContact |
| GLU 55 | b1b2.4 | PRO 31 | - | Hydrophobic |
| GLU 55 | b1b2.4 | PRO 31 | - | VdWContact |
| LEU 56 | b1b2.6 | PHE 24 | - | Hydrophobic |
| LEU 56 | b1b2.6 | GLY 29 | - | VdWContact |
| CYS 57 | b1b2.7 | GLY 29 | - | HBDonor |
| CYS 57 | b1b2.7 | GLY 29 | - | VdWContact |
