Predicted complex interactions
CXCL9_HUMAN + CCR2
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR2 View partner entry
- Partner description
- UniProt: P41597; Gene: ccr2_human; Family: Chemokine
- Interactions detected
- 100
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | GLU 291 | 7.39x38 | HBDonor |
| THR 1 | NTc.Cm30 | GLU 291 | 7.39x38 | VdWContact |
| THR 1 | NTc.Cm30 | MET 295 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 98 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 98 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm29 | THR 117 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TYR 120 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TYR 120 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm29 | HIS 121 | 3.33x33 | Hydrophobic |
| PRO 2 | NTc.Cm29 | PRO 192 | 45.52x52 | VdWContact |
| VAL 3 | NTc.Cm28 | TYR 120 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm28 | HIS 121 | 3.33x33 | Hydrophobic |
| VAL 3 | NTc.Cm28 | ILE 263 | 6.55x55 | Hydrophobic |
| VAL 4 | NTc.Cm27 | ILE 263 | 6.55x55 | Hydrophobic |
| VAL 4 | NTc.Cm27 | THR 287 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm27 | THR 287 | 7.35x34 | VdWContact |
| ARG 5 | NTc.Cm26 | VAL 189 | - | VdWContact |
| ARG 5 | NTc.Cm26 | CYS 190 | 45.50x50 | HBDonor |
| ARG 5 | NTc.Cm26 | CYS 190 | 45.50x50 | VdWContact |
| ARG 5 | NTc.Cm26 | PRO 192 | 45.52x52 | VdWContact |
| LYS 6 | NTc.Cm25 | ASN 266 | 6.58x58 | HBDonor |
| LYS 6 | NTc.Cm25 | ASN 266 | 6.58x58 | VdWContact |
| LYS 6 | NTc.Cm25 | THR 267 | 6.59x59 | HBDonor |
| LYS 6 | NTc.Cm25 | THR 267 | 6.59x59 | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 34 | - | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 284 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 284 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm23 | ASP 284 | 7.32x31 | VdWContact |
| SER 10 | NTc.Cm21 | PRO 31 | - | VdWContact |
| SER 10 | NTc.Cm21 | CYS 32 | - | HBAcceptor |
| SER 10 | NTc.Cm21 | CYS 32 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 32 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | SER 275 | - | VdWContact |
| ILE 12 | NTc.Cm19 | ASN 276 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 277 | - | Hydrophobic |
| SER 13 | NTc.Cm18 | GLY 29 | - | VdWContact |
| THR 14 | NTc.Cm17 | ASP 27 | - | VdWContact |
| ASN 15 | NTc.Cm16 | ASP 27 | - | VdWContact |
| ASN 15 | NTc.Cm16 | TYR 28 | - | HBDonor |
| ASN 15 | NTc.Cm16 | TYR 28 | - | VdWContact |
| GLN 16 | NTc.Cm15 | ASP 27 | - | VdWContact |
| GLY 17 | NTc.Cm14 | ASP 25 | - | VdWContact |
| GLY 17 | NTc.Cm14 | TYR 26 | - | HBAcceptor |
| GLY 17 | NTc.Cm14 | TYR 26 | - | HBDonor |
| GLY 17 | NTc.Cm14 | TYR 26 | - | VdWContact |
| THR 18 | NTc.Cm13 | PHE 23 | - | Hydrophobic |
| THR 18 | NTc.Cm13 | PHE 23 | - | VdWContact |
| THR 18 | NTc.Cm13 | PHE 24 | - | VdWContact |
| THR 18 | NTc.Cm13 | ASP 25 | - | VdWContact |
| THR 18 | NTc.Cm13 | TYR 26 | - | VdWContact |
| ILE 19 | NTc.Cm12 | PHE 23 | - | VdWContact |
| ILE 19 | NTc.Cm12 | PHE 24 | - | HBAcceptor |
| ILE 19 | NTc.Cm12 | PHE 24 | - | HBDonor |
| ILE 19 | NTc.Cm12 | PHE 24 | - | VdWContact |
| ILE 19 | NTc.Cm12 | TYR 26 | - | Hydrophobic |
| ILE 19 | NTc.Cm12 | TYR 26 | - | VdWContact |
| HIS 20 | NTc.Cm11 | THR 21 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | THR 21 | - | VdWContact |
| HIS 20 | NTc.Cm11 | PHE 23 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | PHE 23 | - | VdWContact |
| LEU 21 | NTc.Cm10 | THR 22 | - | VdWContact |
| LEU 21 | NTc.Cm10 | PHE 24 | - | Hydrophobic |
| GLN 22 | NTc.Cm9 | GLU 19 | - | HBDonor |
| GLN 22 | NTc.Cm9 | GLU 19 | - | VdWContact |
| PRO 34 | cxb1.1 | TYR 193 | - | Hydrophobic |
| PRO 34 | cxb1.1 | TYR 193 | - | VdWContact |
| SER 35 | cxb1.2 | GLU 184 | - | HBDonor |
| SER 35 | cxb1.2 | GLU 184 | - | VdWContact |
| SER 35 | cxb1.2 | TYR 193 | - | VdWContact |
| GLU 37 | cxb1.6 | ARG 196 | 5.32x33 | HBAcceptor |
| GLU 37 | cxb1.6 | ARG 196 | 5.32x33 | VdWContact |
| ILE 42 | cxb1.14 | PRO 31 | - | Hydrophobic |
| GLN 50 | B1.6 | PRO 31 | - | Hydrophobic |
| GLN 50 | B1.6 | HIS 33 | - | HBAcceptor |
| GLN 50 | B1.6 | HIS 33 | - | VdWContact |
| THR 51 | B1.7 | TYR 26 | - | Hydrophobic |
| THR 51 | B1.7 | TYR 26 | - | VdWContact |
| THR 51 | B1.7 | TYR 28 | - | VdWContact |
| THR 51 | B1.7 | GLY 29 | - | HBAcceptor |
| THR 51 | B1.7 | GLY 29 | - | VdWContact |
| THR 51 | B1.7 | PRO 31 | - | VdWContact |
| CYS 52 | b1b2.4 | GLY 29 | - | HBDonor |
| CYS 52 | b1b2.4 | GLY 29 | - | VdWContact |
| LEU 53 | b1b2.6 | TYR 26 | - | Hydrophobic |
| LEU 53 | b1b2.6 | TYR 26 | - | VdWContact |
| ASN 54 | b1b2.7 | ASP 27 | - | HBDonor |
| ASN 54 | b1b2.7 | ASP 27 | - | Hydrophobic |
| ASN 54 | b1b2.7 | ASP 27 | - | VdWContact |
| ASP 59 | b1b2.13 | PHE 24 | - | Hydrophobic |
| ASP 59 | b1b2.13 | PHE 24 | - | VdWContact |
| ASP 59 | b1b2.13 | ASP 25 | - | HBAcceptor |
| ASP 59 | b1b2.13 | ASP 25 | - | VdWContact |
| VAL 60 | b1b2.14 | TYR 26 | - | Hydrophobic |
| GLU 62 | B2.1 | PHE 24 | - | Hydrophobic |
| LEU 63 | B2.2 | PHE 24 | - | Hydrophobic |
| LEU 63 | B2.2 | PHE 24 | - | VdWContact |
| LYS 66 | B2.5 | THR 22 | - | HBDonor |
| LYS 66 | B2.5 | THR 22 | - | VdWContact |
| LYS 66 | B2.5 | PHE 24 | - | Hydrophobic |
| LYS 66 | B2.5 | PHE 24 | - | VdWContact |
