Predicted complex interactions
CCL15_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 17 | NTc.Cm36 | ILE 267 | 6.63x63 | Hydrophobic |
| GLU 18 | NTc.Cm35 | SER 266 | 6.62x62 | VdWContact |
| GLU 18 | NTc.Cm35 | ILE 267 | 6.63x63 | Hydrophobic |
| GLU 18 | NTc.Cm35 | ILE 267 | 6.63x63 | VdWContact |
| ASN 19 | NTc.Cm34 | TYR 193 | 5.32x33 | Hydrophobic |
| ASN 19 | NTc.Cm34 | TYR 193 | 5.32x33 | VdWContact |
| ASN 19 | NTc.Cm34 | SER 266 | 6.62x62 | HBAcceptor |
| ASN 19 | NTc.Cm34 | SER 266 | 6.62x62 | VdWContact |
| PRO 20 | NTc.Cm33 | TYR 193 | 5.32x33 | Hydrophobic |
| PRO 20 | NTc.Cm33 | ARG 196 | 5.35x36 | HBAcceptor |
| PRO 20 | NTc.Cm33 | ARG 196 | 5.35x36 | Hydrophobic |
| PRO 20 | NTc.Cm33 | ARG 196 | 5.35x36 | VdWContact |
| PRO 20 | NTc.Cm33 | HIS 197 | 5.36x37 | Hydrophobic |
| PRO 20 | NTc.Cm33 | HIS 197 | 5.36x37 | VdWContact |
| PRO 20 | NTc.Cm33 | SER 263 | 6.59x59 | VdWContact |
| VAL 21 | NTc.Cm32 | SER 262 | 6.58x58 | HBDonor |
| VAL 21 | NTc.Cm32 | SER 262 | 6.58x58 | VdWContact |
| VAL 21 | NTc.Cm32 | GLN 265 | 6.61x61 | Hydrophobic |
| VAL 22 | NTc.Cm31 | ALA 185 | 45.52x52 | Hydrophobic |
| VAL 22 | NTc.Cm31 | TYR 187 | - | Hydrophobic |
| VAL 22 | NTc.Cm31 | ARG 196 | 5.35x36 | Hydrophobic |
| VAL 22 | NTc.Cm31 | ARG 196 | 5.35x36 | VdWContact |
| LEU 23 | NTc.Cm30 | ILE 259 | 6.55x55 | Hydrophobic |
| LEU 23 | NTc.Cm30 | ILE 259 | 6.55x55 | VdWContact |
| LEU 23 | NTc.Cm30 | SER 262 | 6.58x58 | VdWContact |
| LEU 23 | NTc.Cm30 | MET 283 | 7.35x34 | Hydrophobic |
| LEU 23 | NTc.Cm30 | MET 283 | 7.35x34 | VdWContact |
| ASN 24 | NTc.Cm29 | TYR 172 | 4.64x65 | VdWContact |
| ASN 24 | NTc.Cm29 | SER 184 | 45.51x51 | VdWContact |
| ASN 24 | NTc.Cm29 | ALA 185 | 45.52x52 | HBAcceptor |
| ASN 24 | NTc.Cm29 | ALA 185 | 45.52x52 | VdWContact |
| SER 25 | NTc.Cm28 | TYR 113 | 3.32x32 | HBAcceptor |
| SER 25 | NTc.Cm28 | TYR 113 | 3.32x32 | VdWContact |
| SER 25 | NTc.Cm28 | HIS 114 | 3.33x33 | VdWContact |
| SER 25 | NTc.Cm28 | TYR 172 | 4.64x65 | HBDonor |
| SER 25 | NTc.Cm28 | TYR 172 | 4.64x65 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 41 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 41 | 1.39x39 | VdWContact |
| PHE 26 | NTc.Cm27 | LEU 87 | 2.57x57 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 90 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 90 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | VAL 94 | 2.64x64 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 113 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 113 | 3.32x32 | VdWContact |
| HIS 27 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| HIS 27 | NTc.Cm26 | MET 283 | 7.35x34 | Hydrophobic |
| PHE 28 | NTc.Cm25 | ARG 30 | 1.28x28 | Hydrophobic |
| PHE 28 | NTc.Cm25 | ARG 30 | 1.28x28 | VdWContact |
| PHE 28 | NTc.Cm25 | TYR 93 | 2.63x63 | Hydrophobic |
| PHE 28 | NTc.Cm25 | HIS 97 | 2.67x67 | Hydrophobic |
| PHE 28 | NTc.Cm25 | GLU 180 | - | VdWContact |
| PHE 28 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | LEU 182 | - | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 26 | 1.24x24 | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 26 | 1.24x24 | VdWContact |
| ALA 29 | NTc.Cm24 | THR 29 | 1.27x27 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 30 | 1.28x28 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 30 | 1.28x28 | VdWContact |
| ALA 29 | NTc.Cm24 | MET 33 | 1.31x31 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ASP 280 | 7.32x31 | Hydrophobic |
| ALA 30 | NTc.Cm23 | LYS 26 | 1.24x24 | VdWContact |
| ALA 30 | NTc.Cm23 | LEU 182 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | LEU 23 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | CYS 24 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 26 | 1.24x24 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 26 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | ARG 30 | 1.28x28 | Anionic |
| ASP 31 | NTc.Cm22 | ARG 30 | 1.28x28 | HBAcceptor |
| ASP 31 | NTc.Cm22 | ARG 30 | 1.28x28 | VdWContact |
| CYS 32 | NTc.Cm21 | LEU 23 | - | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 24 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 24 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 24 | - | VdWContact |
| THR 34 | NTc.Cm19 | LEU 22 | - | HBDonor |
| THR 34 | NTc.Cm19 | LEU 22 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 24 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 24 | - | VdWContact |
| THR 34 | NTc.Cm19 | ASN 271 | - | HBAcceptor |
| THR 34 | NTc.Cm19 | ASN 271 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 273 | 7.25x24 | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 273 | 7.25x24 | VdWContact |
| SER 35 | NTc.Cm18 | VAL 20 | - | HBDonor |
| SER 35 | NTc.Cm18 | VAL 20 | - | VdWContact |
| SER 35 | NTc.Cm18 | LEU 22 | - | HBAcceptor |
| SER 35 | NTc.Cm18 | LEU 22 | - | VdWContact |
| ILE 37 | NTc.Cm16 | ASP 19 | - | VdWContact |
| SER 38 | NTc.Cm15 | ASP 19 | - | VdWContact |
| PHE 50 | NTc.Cm3 | PHE 178 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | PHE 178 | - | VdWContact |
| SER 53 | CX.1 | GLU 175 | - | HBDonor |
| SER 53 | CX.1 | GLU 175 | - | VdWContact |
| SER 53 | CX.1 | LEU 177 | - | VdWContact |
| SER 54 | CX.5 | GLU 175 | - | HBDonor |
| SER 54 | CX.5 | GLU 175 | - | VdWContact |
| SER 54 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| SER 54 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| CYS 56 | cxb1.2 | ARG 196 | 5.35x36 | HBAcceptor |
| CYS 56 | cxb1.2 | ARG 196 | 5.35x36 | VdWContact |
| SER 57 | cxb1.5 | ARG 196 | 5.35x36 | HBAcceptor |
| SER 57 | cxb1.5 | ARG 196 | 5.35x36 | VdWContact |
| LYS 58 | cxb1.6 | ASN 271 | - | VdWContact |
| ILE 62 | cxb1.11 | LEU 23 | - | Hydrophobic |
| LEU 64 | cxb1.15 | PHE 178 | - | Hydrophobic |
| GLN 70 | B1.5 | LEU 23 | - | VdWContact |
| CYS 72 | B1.7 | GLY 21 | - | HBDonor |
| CYS 72 | B1.7 | GLY 21 | - | VdWContact |
| TYR 90 | b2b3.12 | PHE 178 | - | Hydrophobic |
| TYR 90 | b2b3.12 | PHE 178 | - | PiStacking |
| TYR 90 | b2b3.12 | PHE 178 | - | VdWContact |
| TYR 90 | b2b3.12 | GLU 179 | - | Hydrophobic |
| ILE 92 | B3.2 | PHE 178 | - | VdWContact |
