Predicted complex interactions
CCL2_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 99
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | TRP 90 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TRP 90 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | SER 110 | 3.29x29 | HBDonor |
| GLN 1 | NTc.Cm33 | SER 110 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 172 | 4.64x65 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 172 | 4.64x65 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 172 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | CYS 183 | 45.50x50 | HBDonor |
| GLN 1 | NTc.Cm33 | CYS 183 | 45.50x50 | VdWContact |
| GLN 1 | NTc.Cm33 | SER 184 | 45.51x51 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 90 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 90 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 113 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 287 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 291 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 291 | 7.43x42 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 255 | 6.51x51 | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 255 | 6.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | MET 283 | 7.35x34 | Hydrophobic |
| ASP 3 | NTc.Cm31 | MET 283 | 7.35x34 | VdWContact |
| ASP 3 | NTc.Cm31 | GLU 287 | 7.39x38 | HBDonor |
| ASP 3 | NTc.Cm31 | GLU 287 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | MET 283 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm30 | MET 283 | 7.35x34 | VdWContact |
| ALA 4 | NTc.Cm30 | LEU 284 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm30 | GLU 287 | 7.39x38 | VdWContact |
| ILE 5 | NTc.Cm29 | TYR 41 | 1.39x39 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 41 | 1.39x39 | VdWContact |
| ILE 5 | NTc.Cm29 | TRP 90 | 2.60x60 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TRP 90 | 2.60x60 | VdWContact |
| ILE 5 | NTc.Cm29 | TYR 93 | 2.63x63 | Hydrophobic |
| ILE 5 | NTc.Cm29 | TYR 93 | 2.63x63 | VdWContact |
| ILE 5 | NTc.Cm29 | VAL 94 | 2.64x64 | Hydrophobic |
| ILE 5 | NTc.Cm29 | VAL 94 | 2.64x64 | VdWContact |
| ASN 6 | NTc.Cm28 | TYR 93 | 2.63x63 | HBDonor |
| ASN 6 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| ASN 6 | NTc.Cm28 | CYS 183 | 45.50x50 | VdWContact |
| ALA 7 | NTc.Cm27 | ASP 280 | 7.32x31 | Hydrophobic |
| ALA 7 | NTc.Cm27 | ASP 280 | 7.32x31 | VdWContact |
| ALA 7 | NTc.Cm27 | MET 283 | 7.35x34 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | 1.24x24 | VdWContact |
| PRO 8 | NTc.Cm26 | THR 29 | 1.27x27 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | HBAcceptor |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| PRO 8 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| PRO 8 | NTc.Cm26 | MET 33 | 1.31x31 | VdWContact |
| PRO 8 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| VAL 9 | NTc.Cm25 | LEU 177 | - | Hydrophobic |
| VAL 9 | NTc.Cm25 | LEU 177 | - | VdWContact |
| VAL 9 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 23 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 24 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLU 25 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PHE 178 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PHE 178 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 24 | - | VdWContact |
| TYR 13 | NTc.Cm21 | LYS 26 | 1.24x24 | VdWContact |
| TYR 13 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | ASN 271 | - | VdWContact |
| TYR 13 | NTc.Cm21 | SER 276 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | ASN 271 | - | HBDonor |
| THR 16 | NTc.Cm18 | GLY 21 | - | VdWContact |
| ASN 17 | NTc.Cm17 | ASP 19 | - | HBDonor |
| ASN 17 | NTc.Cm17 | ASP 19 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 16 | - | HBDonor |
| ARG 18 | NTc.Cm16 | TYR 16 | - | VdWContact |
| ARG 18 | NTc.Cm16 | ASP 19 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 19 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 19 | - | VdWContact |
| ARG 29 | NTc.Cm5 | LEU 23 | - | VdWContact |
| ARG 29 | NTc.Cm5 | PHE 178 | - | CationPi |
| ARG 29 | NTc.Cm5 | PHE 178 | - | VdWContact |
| ILE 31 | NTc.Cm3 | PHE 178 | - | Hydrophobic |
| ILE 31 | NTc.Cm3 | PHE 178 | - | VdWContact |
| SER 33 | NTc.Cm1 | GLU 175 | - | HBDonor |
| SER 33 | NTc.Cm1 | GLU 175 | - | VdWContact |
| SER 34 | CX.1 | ALA 185 | 45.52x52 | HBDonor |
| SER 34 | CX.1 | ALA 185 | 45.52x52 | VdWContact |
| SER 34 | CX.1 | ARG 196 | 5.35x36 | HBAcceptor |
| SER 34 | CX.1 | ARG 196 | 5.35x36 | VdWContact |
| LYS 35 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| LYS 35 | CX.5 | ARG 196 | 5.35x36 | VdWContact |
| PRO 37 | cxb1.2 | TYR 193 | 5.32x33 | HBAcceptor |
| PRO 37 | cxb1.2 | TYR 193 | 5.32x33 | VdWContact |
| LYS 38 | cxb1.5 | TYR 193 | 5.32x33 | VdWContact |
| LYS 38 | cxb1.5 | ASN 271 | - | VdWContact |
| ILE 42 | cxb1.10 | LEU 23 | - | Hydrophobic |
| ILE 42 | cxb1.10 | LEU 23 | - | VdWContact |
| ILE 51 | B1.5 | GLY 21 | - | VdWContact |
| CYS 52 | B1.6 | GLY 21 | - | HBDonor |
| CYS 52 | B1.6 | GLY 21 | - | VdWContact |
