Predicted complex interactions
CCL21_HUMAN + CCR3
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR3 View partner entry
- Partner description
- UniProt: P51677; Gene: ccr3_human; Family: Chemokine
- Interactions detected
- 73
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | GLU 287 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 287 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 287 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm28 | TYR 93 | 2.63x63 | VdWContact |
| ALA 5 | NTc.Cm26 | LYS 26 | 1.24x24 | Hydrophobic |
| ALA 5 | NTc.Cm26 | LYS 26 | 1.24x24 | VdWContact |
| ALA 5 | NTc.Cm26 | THR 29 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ARG 30 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ARG 30 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm26 | MET 33 | 1.31x31 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ASP 280 | 7.32x31 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ASP 280 | 7.32x31 | VdWContact |
| GLN 6 | NTc.Cm25 | LYS 26 | 1.24x24 | VdWContact |
| GLN 6 | NTc.Cm25 | LEU 182 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | CYS 24 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LYS 26 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm24 | LYS 26 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 30 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm24 | ARG 30 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm24 | ARG 30 | 1.28x28 | VdWContact |
| CYS 8 | NTc.Cm23 | LEU 23 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 24 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 24 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | ASN 271 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | ASN 271 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 273 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 273 | 7.25x24 | VdWContact |
| LYS 11 | NTc.Cm20 | ASN 271 | - | Hydrophobic |
| LYS 11 | NTc.Cm20 | ASN 271 | - | VdWContact |
| TYR 12 | NTc.Cm19 | GLY 21 | - | VdWContact |
| SER 13 | NTc.Cm18 | VAL 20 | - | VdWContact |
| GLN 14 | NTc.Cm17 | ASP 19 | - | HBDonor |
| GLN 14 | NTc.Cm17 | ASP 19 | - | VdWContact |
| ARG 15 | NTc.Cm16 | TYR 16 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 19 | - | Cationic |
| ARG 26 | NTc.Cm5 | PHE 178 | - | CationPi |
| ARG 26 | NTc.Cm5 | PHE 178 | - | VdWContact |
| GLU 29 | NTc.Cm2 | LEU 186 | - | Hydrophobic |
| PRO 30 | NTc.Cm1 | TYR 187 | - | VdWContact |
| PRO 30 | NTc.Cm1 | VAL 192 | 5.31x32 | Hydrophobic |
| PRO 30 | NTc.Cm1 | VAL 192 | 5.31x32 | VdWContact |
| SER 31 | CX.1 | ALA 185 | 45.52x52 | VdWContact |
| LEU 32 | CX.5 | TYR 172 | 4.64x65 | Hydrophobic |
| LEU 32 | CX.5 | ALA 185 | 45.52x52 | Hydrophobic |
| LEU 32 | CX.5 | TYR 187 | - | Hydrophobic |
| LEU 32 | CX.5 | ARG 196 | 5.35x36 | HBAcceptor |
| LEU 32 | CX.5 | ARG 196 | 5.35x36 | Hydrophobic |
| LEU 32 | CX.5 | HIS 199 | 5.38x39 | Hydrophobic |
| SER 35 | cxb1.5 | ARG 196 | 5.35x36 | VdWContact |
| LEU 40 | cxb1.11 | LEU 23 | - | Hydrophobic |
| LEU 42 | cxb1.15 | PHE 178 | - | Hydrophobic |
| LEU 42 | cxb1.15 | PHE 178 | - | VdWContact |
| ALA 49 | B1.6 | LEU 22 | - | Hydrophobic |
| GLU 50 | B1.7 | LEU 23 | - | HBAcceptor |
| GLU 50 | B1.7 | LEU 23 | - | Hydrophobic |
| GLU 50 | B1.7 | LEU 23 | - | VdWContact |
| GLU 50 | B1.7 | PHE 178 | - | VdWContact |
| LEU 51 | b1b2.4 | VAL 20 | - | Hydrophobic |
| LEU 51 | b1b2.4 | VAL 20 | - | VdWContact |
| LEU 51 | b1b2.4 | LEU 22 | - | Hydrophobic |
| CYS 52 | b1b2.6 | GLY 21 | - | HBDonor |
| CYS 52 | b1b2.6 | GLY 21 | - | VdWContact |
| LYS 75 | B3.3 | GLU 175 | - | Cationic |
| LYS 75 | B3.3 | GLU 175 | - | HBDonor |
| LYS 75 | B3.3 | GLU 175 | - | Hydrophobic |
| LYS 75 | B3.3 | GLU 175 | - | VdWContact |
| LYS 75 | B3.3 | GLU 176 | - | VdWContact |
| LYS 75 | B3.3 | LEU 177 | - | VdWContact |
| GLN 78 | b3h.2 | GLU 173 | - | HBDonor |
| GLN 78 | b3h.2 | GLU 173 | - | VdWContact |
